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Jon Jacobson
Delivering the 31st Sophia Gray Memorial Lecture and Exhibition in Bloemfontein, was Jon Jacobson from Metropolis Design in Cape Town.

What is inside and what is outside? What is coming alive in the light? Minimalism. Hugeness. Shadows. Soft. Art. Complex. Conversation. Ambiguity. Clarity. All phrases and words used by the most recent Sophia Gray laureate, Jon Jacobson from Metropolis Design in Cape Town, to describe aspects of his work.

He delivered the 31st Sophia Gray memorial lecture in Bloemfontein. The name of his lecture at this prestigious event, organised by the UUFS Department of Architecture, was in [de] finite. Jacobson is the first graduate in the department’s MArch with Design.

Nature plays a big role in many of his projects, with a blurred distinction between the inside and the outside of the structures he builds. His designs fulfil the desire of a union with nature. 

A detailed investigation

Jacobson creates places and spaces to celebrate being. “Architecture is undeniably art, but it is also embodied in the completeness of the lived moment,” he says. 

Every project starts with a detailed investigation. “What social theory will we engage with? How progressive is it? What attitude will we take to the environment, to the theory of family? What other personal concerns will we be worried about? It is important to engage critically with this information. Important to build a philosophical base for each project,” says Jacobson.

He also believes it is important to consciously ensure that form follows idea with the same intensity that it follows function and that it does not blindly follow other form. 

At Metropolis, Jon and his team are client centred in their approach to design. Jon explains the process: “Some of the content is brought from the client’s personal and social aspiration and some from contemporary architecture culture, but the most potent component is the hidden set of ideas that emerge from our own engagements with the living world such as popular science, geology, art, music, literature, philosophy, theology, mysticism, and many others. And this emerges in the hidden sense of the word, in its architecture content.”

Content approach to design

In house design, Jon categorises the content that informs the architecture of the house: content pertaining to the individual, their philosophy, values and beliefs, content derived from culture, architecture and the arts, passion, religion, politics, and content referring to the natural world and its processes. Content from each of these spheres is present in any of his work. 

Jon says a major implication of a content approach to design is that it requires a design framework that is largely operative at a level of idea rather than at the level of form. This contributes to creating architecture rather than just buildings. 

His design method allows conscious control over the relationship between the ideas, the forms, and the poetics of the projects. “And at any point in the building process, it is possible to trace back and to critically assess whether any particular form is aligning with the core ideas of the project,” Jon indicates. 

Jon’s first taste of grappling with the infinite of architecture was with a garden pavilion he built for rest and relaxation. “For the first time I felt that we integrated planning, content, sight, programme, structure, and materiality into one unified whole that was expressed with a minimum of means and that was more than just the sum of its part,” he states.

He strongly believes that the individual is at the centre of every architectural project. He says the belief systems, type of social needs, family dynamics, physical habits, and spatial practices of their clients need to be investigated in detail in order to facilitate a meaningful spatial experience.

He continues: “We see our role as designers to saturate the environment with the meaning that enhances our clients’ daily experience in every possible way – from the ergonomic and the practical to the spiritual. In the process, the logics and tradition of architecture and the ego of the architect sometimes need to make way for human need and aspiration.”


News Archive

UFS study on cell development in top international science journal
2008-09-16

A study from the University of the Free State (UFS) on how the change in the packaging of DNA with cell development influenced the expression of genes, will be published in this week’s early edition of the prestigious international, peer-reviewed science journal, the Proceeding of the National Academy of Sciences of the USA (PNAS).

The PNAS journal has an impact factor of 10, which means that studies published in the journal are, on average, referred to by ten other scientific studies in a two year period. The South African Journal of Science, by comparison, has an impact factor of 0.7.

The UFS study, funded by the Wellcome Trust and the National Research Foundation (NRF), looked at how the change in the packaging of DNA with cell development influenced the expression of genes. It is very relevant to research on stem cells, an area of medicine that studies the possible use of undifferentiated cells to replace damaged tissue.

Prof. Hugh Patterton, of the Department of Microbial, Biochemical and Food Biotechnology at the UFS, who led the study, said: "We are extremely proud of this study. It was conceived in South Africa, it was performed in South Africa, the data were analysed in South Africa, and it was published from South Africa."

When a gene is expressed, the information encoded in the gene is used to manufacture a specific protein. In eukaryotes, which include humans, there is approximately 1m of DNA, containing the genes, in every cell. This length of DNA has to fit into a cell nucleus with a diameter of only about 10 micrometer. In order to fit the DNA into such a small volume, eukaryotic cells wrap their DNA onto successive protein balls, termed nucleosomes. Strings of nucleosomes, resembling a bead of pearls, is folded into a helix to form a chromatin fiber. The study from the UFS investigated how the binding of a specific protein, termed a linker histone, that binds to the length of DNA between nucleosomes, influenced the formation of the chromatin fiber and also the activity of genes.

"We found that the linker histone bound to chromatin in yeast, which we use as a model eukaryote, under conditions where virtually all the genes in the organism were inactive. It was widely believed that the binding of the linker histone caused the inactivation of genes. We studied the relationship between the amount of linker histone bound in the vicinity of each gene and the expression of that gene for all the genes in yeast, using genomic techniques. We made the surprising discovery that even through the linker histone preferentially bound to genes under conditions where the genes were shut off, this inactivation of genes was not caused by the binding of the linker histone and folding of the chromatin,” said Prof. Patterton.

He said: “Instead our data strongly suggested that the observed anti-correlation was due to the movement of enzymes along the DNA molecule, involved in processing the information in genes for the eventual manufacture of proteins. This movement of enzymes displaced the linker histones from the DNA. This finding now requires a rethink on aspects of how packaging of DNA influences gene activity."

Prof. Patterton said that his research group, using the Facility for Genomics and Proteomics as well as the Bioinformatics Node at the UFS, was currently busy with follow-up studies to understand how other proteins in nucleosomes affected the activities of genes, as well as with projects to understand how chemicals found in red wine and in green tea extended lifespan. "We are certainly having a marvelous time trying to understand the fundamental mechanisms of life, and the UFS is an exciting place to be if one was interested in studying life at the level of molecules," he said.


Media Release
Issued by: Lacea Loader
Assistant Director: Media Liaison
Tel: 051 401 2584
Cell: 083 645 2454
E-mail: loaderl.stg@ufs.ac.za  
18 September 2008
 

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