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02 September 2019 | Story Xolisa Mnukwa | Photo Xolisa Mnukwa
Shannon Arnold and Samkezi Mbalane
Shannon Arnold (left) and Samkezi Mbalane (right), the 2019 UFS recipients of the prestigious International Abe Bailey Travel Bursary.

The University of the Free State (UFS) has selected MPhil (African Studies) student and self-proclaimed ‘radical feminist’, Shannon Arnold, and former Golden Key UFS Qwaqwa Campus Chapter President and Political Studies and Governance honours student, Samkezi Mbalane, to represent the institution this year on the Abe Bailey Travel Bursary tour

The Abe Bailey Travel Bursary is a leadership-development programme that honours and targets university students or junior lecturers with a strong academic background, and who have shown exceptional qualities of leadership and service during their university careers as well as in a wider social context. Recipients of the bursary are expected to function as an integral part of a select and highly skilled group of individuals who will be embarking on a five-stage tour in December, starting in Cape Town (South Africa) and finishing in London (United Kingdom).

“Success comes from a feeling of satisfaction in what I have done for myself” – Shannon Arnold

Shannon Arnold, who is originally from Grahamstown, Eastern Cape, completed her undergraduate and honours studies in Political and International Studies and English Literature at Rhodes University. She moved to the UFS and is currently completing her transdisciplinary MPhil in African Studies, focused on Peace and Conflict in Post-conflict African Societies from a gendered perspective. 

“Moving to the Free State was an interesting cultural transition,” Arnold remarked. 
She further expressed how “pleasantly enlightened” she was by the UFS’s active and direct approach to transformation, and how it allowed her to spearhead and coordinate crucial student-movement initiatives such as the total shutdown protest which saw women and students march from the UFS Bloemfontein Campus to the Supreme Court of Appeal in 2018. Arnold believes that her passion, work, and experiences with community and service-based organisations against South Africa’s plight of gender-based violence has branded her a leader and qualified her for becoming an ‘Abe’.

Arnold grew up in a community-minded family and has thus been aligned with politics from a very young age. She is inspired by the thought of manifesting a reality where women in South Africa are able to pursue their own choices. She looks forward to exposing herself to foreign cultures on the tour to the UK, engaging with people who have like-minded convictions. 

“The desire and compassion to motivate and uplift others is what inspires me.”  – Samkezi Mbalane

Eastern Cape, Mount Fletcher-born Samkezi Mbalane, who graduated from the UFS with his undergraduate degree in Political Studies and Governance (Cum Laude), labels his life journey as ‘very difficult, yet fascinating’. 

Having been raised by a struggling single mother, he reflects on being dependant on other people in his immediate community for basic needs. He lived in a foster home for three years (Grade 10 to 12) as a means of survival. Mbalane explained that such experiences motivated him to pursue a career in politics, as he dreams of playing a pivotal role in the creation and implementation of South African governmental policies that will one day effectively benefit the poor.

Mbalane believes his claim to leadership came through ‘hard work and persistence’. He has served in various leadership positions, including President of the Golden Key Society UFS Qwaqwa Campus Chapter, Prime at Steve Biko Residence, active member of the Institute for Reconciliation and Social Justice, Enactus, and the Secretary General of the Student Parliament. Mbalane deemed being selected an ‘Abe’ as an “iconic opportunity for all aspirant leaders in South Africa.” 

He looks forward to working with people from different cultural backgrounds and career fields, but mostly, to seeing the world outside South Africa from a unique perspective.

News Archive

UFS study on cell development in top international science journal
2008-09-16

A study from the University of the Free State (UFS) on how the change in the packaging of DNA with cell development influenced the expression of genes, will be published in this week’s early edition of the prestigious international, peer-reviewed science journal, the Proceeding of the National Academy of Sciences of the USA (PNAS).

The PNAS journal has an impact factor of 10, which means that studies published in the journal are, on average, referred to by ten other scientific studies in a two year period. The South African Journal of Science, by comparison, has an impact factor of 0.7.

The UFS study, funded by the Wellcome Trust and the National Research Foundation (NRF), looked at how the change in the packaging of DNA with cell development influenced the expression of genes. It is very relevant to research on stem cells, an area of medicine that studies the possible use of undifferentiated cells to replace damaged tissue.

Prof. Hugh Patterton, of the Department of Microbial, Biochemical and Food Biotechnology at the UFS, who led the study, said: "We are extremely proud of this study. It was conceived in South Africa, it was performed in South Africa, the data were analysed in South Africa, and it was published from South Africa."

When a gene is expressed, the information encoded in the gene is used to manufacture a specific protein. In eukaryotes, which include humans, there is approximately 1m of DNA, containing the genes, in every cell. This length of DNA has to fit into a cell nucleus with a diameter of only about 10 micrometer. In order to fit the DNA into such a small volume, eukaryotic cells wrap their DNA onto successive protein balls, termed nucleosomes. Strings of nucleosomes, resembling a bead of pearls, is folded into a helix to form a chromatin fiber. The study from the UFS investigated how the binding of a specific protein, termed a linker histone, that binds to the length of DNA between nucleosomes, influenced the formation of the chromatin fiber and also the activity of genes.

"We found that the linker histone bound to chromatin in yeast, which we use as a model eukaryote, under conditions where virtually all the genes in the organism were inactive. It was widely believed that the binding of the linker histone caused the inactivation of genes. We studied the relationship between the amount of linker histone bound in the vicinity of each gene and the expression of that gene for all the genes in yeast, using genomic techniques. We made the surprising discovery that even through the linker histone preferentially bound to genes under conditions where the genes were shut off, this inactivation of genes was not caused by the binding of the linker histone and folding of the chromatin,” said Prof. Patterton.

He said: “Instead our data strongly suggested that the observed anti-correlation was due to the movement of enzymes along the DNA molecule, involved in processing the information in genes for the eventual manufacture of proteins. This movement of enzymes displaced the linker histones from the DNA. This finding now requires a rethink on aspects of how packaging of DNA influences gene activity."

Prof. Patterton said that his research group, using the Facility for Genomics and Proteomics as well as the Bioinformatics Node at the UFS, was currently busy with follow-up studies to understand how other proteins in nucleosomes affected the activities of genes, as well as with projects to understand how chemicals found in red wine and in green tea extended lifespan. "We are certainly having a marvelous time trying to understand the fundamental mechanisms of life, and the UFS is an exciting place to be if one was interested in studying life at the level of molecules," he said.


Media Release
Issued by: Lacea Loader
Assistant Director: Media Liaison
Tel: 051 401 2584
Cell: 083 645 2454
E-mail: loaderl.stg@ufs.ac.za  
18 September 2008
 

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