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10 September 2019 | Story Rulanzen Martin | Photo Rulanzen Martin
Lingustics
Delegates at the workshop were provided opportunities that many larger conferences do not offer.

The growing body of work examining microvariation in African languages prompted Dr Kristina Riedel and Dr Hannah Gibson, from the University of Essex and research fellow, to work on a research project, “Variation in Sesotho and Setswana as spoken in the Free State”, to document the dialectal variation in the languages as it is spoken in the province. 

“Dr Gibson and I have a joint research project which is funded by a Newton British Academy mobility grant,” says Dr Riedel, Head of the Department of Linguistic and Language Practice at the University of the Free State (UFS).

The duo hosted a workshop on morphosyntactic microvariation (small structural differences that can be observed between closely related languages or dialects) on the UFS Bloemfontein Campus, as part of the Newton Fund research project.  

Research focus on dialectal variation 

Dr Riedel says there has been some linguistic work on both of these languages. “But for Sesotho, linguists have noted that there is no dialectal variation. This seems hard to believe given the size of the population who speak the language,” she says. 

They are looking at speakers in the Free State province for differences in both languages. Speakers themselves also report awareness of dialectal differences and variation between different regions. “We’re also interested in whether they have influenced each other – particularly in places where people speak both of these languages on a day-to-day basis, such as Thaba ’Nchu and Bloemfontein,” Dr Riedel says.

Dr Riedel believes that in the context of an African university it is important to contribute to the development, teaching and support of African languages. “Research on African languages can play an important part of this picture. Furthering our knowledge and understanding of African languages from a linguistic perspective also contributes to our understanding of the world’s languages and linguistic diversity.” 

Workshop creates space for training and skill sharing

The aim of the workshop was to bring together researchers, students and language practitioners to “provide them with some of the insights and training that is helpful when looking at morphosyntactic microvariation”, Dr Riedel says.

The workshop was conducted in two sets. At the first workshop the emphasis was on training and sharing of skills and the second part focused on more research-related presentations. 

The workshop, which took place on 19 July 2019, was attended by delegates from numerous local institutions (Rhodes University, University of the Western Cape and Stellenbosch University) as well as universities in the rest of Africa including the University of Malawi, Dar es Salaam University College of Education and Makerere University in Uganda. 

News Archive

#Women'sMonth: Save the children
2017-08-10

Description: Trudi O'Neill Tags: : rotaviruses, young children, Dr Trudi O’Neill, Department of Microbial, Biochemical and Food Biotechnology, vaccine 

Dr Trudi O’Neill, Senior lecturer in the Department of
Microbial, Biochemical and Food Biotechnology.
Photo: Anja Aucamp

Dr Trudi O’Neill, Senior lecturer in the Department of Microbial, Biochemical and Food Biotechnology, is conducting research on rotavirus vaccines.

Dr O’Neill was inspired to conduct research on this issue through her fascination with the virus. “The biology of rotaviruses, especially the genome structure and the virus’ interaction with the host, is fascinating.”

“In fact, it is estimated that, globally, ALL children will be infected with rotavirus before the age of five, irrespective of their socio-economic standing. However, infants and young children in poor countries are more vulnerable due to inadequate healthcare. The WHO estimates that approximately 215 000 deaths occur each year. This roughly equates to eight Airbus A380 planes, the largest commercial carrier with a capacity of approximately 500 seats, filled with only children under the age of five, crashing each week of every year.”

Alternative to expensive medicines 
“Currently, there are two vaccines that have been licensed for global use. However, these vaccines are expensive and poor countries, where the need is the greatest, are struggling to introduce them sustainably. It is therefore appealing to study rotaviruses, as it is scientifically challenging, but could at the same time have an impact on child health,” Dr O’Neill said.

The main focus of Dr O’Neill’s research is to develop a more affordable vaccine that can promote child vaccination in countries/areas that cannot afford the current vaccines.

All about a different approach 

When asked about the most profound finding of her research, Dr O’Neill responded: “It is not so much a finding, but rather the approach. My rotavirus research group is making use of yeast as vehicle to produce a sub-unit vaccine. These microbes are attractive, as they are relatively easy to manipulate and cheap to cultivate. Downstream production costs can therefore be reduced. The system we use was developed by my colleagues, Profs Koos Albertyn and Martie Smit, and allows for the potential use of any yeast. This enables us to screen a vast number of yeasts in order to identify the best yeast producer.”

Vaccination recently acquired a bad name in the media for its adverse side effects. As researcher, Dr O’Neill has this to say: “Vaccines save lives. By vaccinating your child, you don’t just protect your own child from a potentially deadly infection, but also other children in your community that might be too young to be vaccinated or have pre-existing health problems that prevents vaccination.” 

A future without rotavirus vaccination?

Dr O’Neill believes a future without rotavirus vaccination will be a major step backwards, as the impact of rotavirus vaccines has been profound. “Studies in Mexico and Malawi actually show a reduction in deaths. A colleague in Mozambique has commented on the empty hospital beds that amazed both clinicians and scientists only one year after the introduction of the vaccine in that country. Although many parents, mostly in developed countries, don’t have to fear dehydrating diarrhoea and potential hospitalisation of their babies due to rotavirus infection anymore, such an infection could still be a death sentence in countries that have not been able to introduce the vaccine in their national vaccination programmes,” she said. 

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