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UFS says no to gender-based violence

09 September 2019 | Story Valentino Ndaba | Photo Charl Devenish

Silent march — Students and staff marched in solidarity with other South African universities against gender-based violence.

“Now is a time for us as men to say from the bottom of our hearts that indeed we are ashamed. Not only are we ashamed, we will speak and act against any form of violence. The very same people you see here are the very same people we need to protect, and if we do not protect them then we are rotten fruits,” said Katleho Lechoo, President of the Student Representative Council (SRC) at a silent march against gender-based violence held on the Bloemfontein Campus.

On Friday 6 September 2019, the University of the Free State (UFS) executive management and the SRC suspended all academic activities on its three campuses as a gesture of solidarity with the national movement opposing the rape, murder, and abuse of women across the country. A prayer service was also held on the Qwaqwa Campus. The UFS community came out in numbers to mourn victims and stand in support with survivors and those affected by gender-based violence

Remembering Uyinene, Jesse, and many others
Prof Francis Petersen, UFS Rector and Vice-Chancellor, said the recent rape and murder of 19-year-old Media and Film Studies student at the University of Cape Town (UCT), Uyinene Mrwetyana, and the murder of University of Western Cape (UWC) student, Jesse Hess, are painful reminders of the pervasive nature of misogyny and patriarchal violence that impedes the freedom of women in South Africa. “The UFS stands in solidarity with UCT and UWC and all other SA universities that are currently steeped in this national crisis,” he said.

Prof Petersen then called on the Department of Higher Education, civil society, the business sector, and all other roleplayers to actively contribute to efforts to eradicate gender violence. “As a university, we call specifically on the city of Bloemfontein, the mayor, members of local government, the South Africa Police Service and all inhabitants to assist us in making our city safe.”

Reading from the statement of commitment declaring the position of the UFS, Prof Petersen said: “In light of the ongoing violence against women and the recent surge of femicide in SA, the UFS commits itself to challenge, fight, and eradicate all forms of gender-based violence on its campuses and in our country.”

Cry our beloved country
At the end of the proceedings, Prof Puleng LenkaBula called for change, following emotive addresses by student leaders. “The poem and the speeches that have been made are demonstrative of the woundedness of our hearts, of our souls, of our bodies, and the fact that women’s bodies have been made a battleground. Therefore as a university it is important that we recommit ourselves to ensuring that our legs and our thighs do not define us but who we are as human beings is respected,” said the Vice-Rector: Institutional Change, Student Affairs, and Community Engagement.

“Enough is enough!”

Related:

University of the Free State's position on Gender-Based violence

News Archive

UFS study on cell development in top international science journal

2008-09-16

A study from the University of the Free State (UFS) on how the change in the packaging of DNA with cell development influenced the expression of genes, will be published in this week’s early edition of the prestigious international, peer-reviewed science journal, the Proceeding of the National Academy of Sciences of the USA (PNAS).

The PNAS journal has an impact factor of 10, which means that studies published in the journal are, on average, referred to by ten other scientific studies in a two year period. The South African Journal of Science, by comparison, has an impact factor of 0.7.

The UFS study, funded by the Wellcome Trust and the National Research Foundation (NRF), looked at how the change in the packaging of DNA with cell development influenced the expression of genes. It is very relevant to research on stem cells, an area of medicine that studies the possible use of undifferentiated cells to replace damaged tissue.

Prof. Hugh Patterton, of the Department of Microbial, Biochemical and Food Biotechnology at the UFS, who led the study, said: "We are extremely proud of this study. It was conceived in South Africa, it was performed in South Africa, the data were analysed in South Africa, and it was published from South Africa."

When a gene is expressed, the information encoded in the gene is used to manufacture a specific protein. In eukaryotes, which include humans, there is approximately 1m of DNA, containing the genes, in every cell. This length of DNA has to fit into a cell nucleus with a diameter of only about 10 micrometer. In order to fit the DNA into such a small volume, eukaryotic cells wrap their DNA onto successive protein balls, termed nucleosomes. Strings of nucleosomes, resembling a bead of pearls, is folded into a helix to form a chromatin fiber. The study from the UFS investigated how the binding of a specific protein, termed a linker histone, that binds to the length of DNA between nucleosomes, influenced the formation of the chromatin fiber and also the activity of genes.

"We found that the linker histone bound to chromatin in yeast, which we use as a model eukaryote, under conditions where virtually all the genes in the organism were inactive. It was widely believed that the binding of the linker histone caused the inactivation of genes. We studied the relationship between the amount of linker histone bound in the vicinity of each gene and the expression of that gene for all the genes in yeast, using genomic techniques. We made the surprising discovery that even through the linker histone preferentially bound to genes under conditions where the genes were shut off, this inactivation of genes was not caused by the binding of the linker histone and folding of the chromatin,” said Prof. Patterton.

He said: “Instead our data strongly suggested that the observed anti-correlation was due to the movement of enzymes along the DNA molecule, involved in processing the information in genes for the eventual manufacture of proteins. This movement of enzymes displaced the linker histones from the DNA. This finding now requires a rethink on aspects of how packaging of DNA influences gene activity."

Prof. Patterton said that his research group, using the Facility for Genomics and Proteomics as well as the Bioinformatics Node at the UFS, was currently busy with follow-up studies to understand how other proteins in nucleosomes affected the activities of genes, as well as with projects to understand how chemicals found in red wine and in green tea extended lifespan. "We are certainly having a marvelous time trying to understand the fundamental mechanisms of life, and the UFS is an exciting place to be if one was interested in studying life at the level of molecules," he said.

Media Release
Issued by: Lacea Loader
Assistant Director: Media Liaison
Tel: 051 401 2584
Cell: 083 645 2454
E-mail: loaderl.stg@ufs.ac.za
18 September 2008

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