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26 August 2020 | Story Nitha Ramnath | Photo Supplied

A VUCA environment reflects a state of the external world, or external to the leader, community, or nation, as much as it seems to reflect an internal frame of mind. The constant pressure to lead, while being uncertain about the outcomes of your decisions and even fearful of not being in control all the time, are some of the hallmarks of a VUCA world. A good way of thinking about this concept is to view it as the ‘new narrative’ – the volatility, uncertainty, complexity, and ambiguity inherent in today’s world.

Leaders in the 21st century need to steer a country securely through unparalleled, challenging, and stormy circumstances such as food insecurity, political unrest, migration and refugee issues, unemployment, divided societies and prejudice, global warming, and others. Against this introduction, it unfortunately appears as if there is an increase in VUCA problems in the 21st century, and leaders often fail in their attempts to provide solutions to these demanding circumstances. Indeed, it appears as if leaders in the 21st century are actually contributing to VUCA environments. So-called ‘state capture’ and the ‘gangster state’ in South Africa, ‘make America great again’ and ‘America first’ , the Brexit no-deal option, ‘trade wars’, and ‘the deadly coronavirus’ are examples of when leaders did not appear to solve challenges, but rather to intensify them. 

This is the backdrop against which the book, Chaos is a Gift? Leading Oneself in Uncertain and Complex Environments, has been conceptualised – indeed to debate the opportunities that exist amid this chaos. 

Three UFS women academics contributed to this book.

Dr Martha Harunavamwe (Department of Industrial Psychology) has written a chapter on resilience and agility in Zimbabwean higher education.Dr Mareve Biljohn (Department of Public Administration and Management) has written a chapter on leading the self in South Africa’s VUCA local government environments. Prof Liezel Lues (Department of Public Administration and Management) has written a chapter on South Africa’s surviving VUCA environment. She is also one of the editors of the book.

The endorsement written by Prof Petersen, reads: There are various books on leadership, but this book, in navigating today’s volatile, uncertain, complex and ambiguous (VUCA) environment, presents chaos as both an opportunity and possibility in developing ‘selfcare practices’ in leading oneself. Leaders must have the cognitive flexibility to adapt to the unknown in the midst of chaos (and a crisis). Through making sense of leadership approaches in different environments, including the business, private, academic and public sectors, as well as in conflict/post-conflict situations, the book provides a deep insight into leading oneself effectively with innovation and empathy in a VUCA environment – an excellent contribution to self-leadership. (Francis Petersen, Rector and Vice-Chancellor: Top Management, University of the Free State)

The book, published by KR Publishers, will be launched on 27 August 2020. Prof Ebben van Zyl, together with Prof Lues, are the editors of this book: Van Zyl, E, Campbell, A and Lues, L. ed. Chaos is a Gift? Leading Oneself in Uncertain and Complex Environments. Randburg: KR Publishing. ISBN: 978-1-86922-860-6

News Archive

UFS study on cell development in top international science journal
2008-09-16

A study from the University of the Free State (UFS) on how the change in the packaging of DNA with cell development influenced the expression of genes, will be published in this week’s early edition of the prestigious international, peer-reviewed science journal, the Proceeding of the National Academy of Sciences of the USA (PNAS).

The PNAS journal has an impact factor of 10, which means that studies published in the journal are, on average, referred to by ten other scientific studies in a two year period. The South African Journal of Science, by comparison, has an impact factor of 0.7.

The UFS study, funded by the Wellcome Trust and the National Research Foundation (NRF), looked at how the change in the packaging of DNA with cell development influenced the expression of genes. It is very relevant to research on stem cells, an area of medicine that studies the possible use of undifferentiated cells to replace damaged tissue.

Prof. Hugh Patterton, of the Department of Microbial, Biochemical and Food Biotechnology at the UFS, who led the study, said: "We are extremely proud of this study. It was conceived in South Africa, it was performed in South Africa, the data were analysed in South Africa, and it was published from South Africa."

When a gene is expressed, the information encoded in the gene is used to manufacture a specific protein. In eukaryotes, which include humans, there is approximately 1m of DNA, containing the genes, in every cell. This length of DNA has to fit into a cell nucleus with a diameter of only about 10 micrometer. In order to fit the DNA into such a small volume, eukaryotic cells wrap their DNA onto successive protein balls, termed nucleosomes. Strings of nucleosomes, resembling a bead of pearls, is folded into a helix to form a chromatin fiber. The study from the UFS investigated how the binding of a specific protein, termed a linker histone, that binds to the length of DNA between nucleosomes, influenced the formation of the chromatin fiber and also the activity of genes.

"We found that the linker histone bound to chromatin in yeast, which we use as a model eukaryote, under conditions where virtually all the genes in the organism were inactive. It was widely believed that the binding of the linker histone caused the inactivation of genes. We studied the relationship between the amount of linker histone bound in the vicinity of each gene and the expression of that gene for all the genes in yeast, using genomic techniques. We made the surprising discovery that even through the linker histone preferentially bound to genes under conditions where the genes were shut off, this inactivation of genes was not caused by the binding of the linker histone and folding of the chromatin,” said Prof. Patterton.

He said: “Instead our data strongly suggested that the observed anti-correlation was due to the movement of enzymes along the DNA molecule, involved in processing the information in genes for the eventual manufacture of proteins. This movement of enzymes displaced the linker histones from the DNA. This finding now requires a rethink on aspects of how packaging of DNA influences gene activity."

Prof. Patterton said that his research group, using the Facility for Genomics and Proteomics as well as the Bioinformatics Node at the UFS, was currently busy with follow-up studies to understand how other proteins in nucleosomes affected the activities of genes, as well as with projects to understand how chemicals found in red wine and in green tea extended lifespan. "We are certainly having a marvelous time trying to understand the fundamental mechanisms of life, and the UFS is an exciting place to be if one was interested in studying life at the level of molecules," he said.


Media Release
Issued by: Lacea Loader
Assistant Director: Media Liaison
Tel: 051 401 2584
Cell: 083 645 2454
E-mail: loaderl.stg@ufs.ac.za  
18 September 2008
 

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