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14 August 2020 | Story Andre Damons | Photo Supplied
Max du Preez, Editor: Vrye Weekblad (top left), was the facilitator was the facilitator for Thursday’s UFS Though-Leader webinar that included Prof Salim Abdool Karim, Director: Centre for the AIDS Programme of Research in South Africa (CAPRISA) and Chair: South African Ministerial Advisory Committee on COVID-19 (top right); Prof Glenda Gray, President and CEO: South African Medical Research Council (SAMRC) (bottom left); and Prof Felicity Burt from the UFS and NRF-DST South African Research Chair in Vector-borne and Zoonotic Pathogens Research (bottom right), participated in Thursday’s Though-Leader webinar.

Although the decline in COVID-19 cases is a promising sign for South Africa, there are concerns about a second surge, and the country should not become complacent.

This was the opinion of the three experts who took part in the first Thought-Leader webinar presented by the University of the Free State (UFS) on Thursday, 13 August. The 2020 UFS Thought-Leader Webinar Series, themed 'Post-COVID-19, Post-Crisis', is taking place in collaboration with Vrye Weekblad as part of the Vrystaat Literature Festival’s online initiative, VrySpraak-digitaal.

The panellists included top experts such as Prof Salim Abdool Karim, Director: Centre for the AIDS Programme of Research in South Africa (CAPRISA) and Chair: South African Ministerial Advisory Committee on COVID-19; Prof Glenda Gray, President and CEO: South African Medical Research Council (SAMRC); and the UFS’ Prof Felicity Burt, NRF-DST South African Research Chair in Vector-borne and Zoonotic Pathogens Research.
Prof Karim said the downward decline is consistent and the number of patients presenting at hospitals is also declining.
 
Promising trend of decline
“What we are seeing is a promising trend, and it looks like we are on the decline. A question that I am often asked is: Is the worst over? The answer is not clear-cut. We are concerned about the risk of a second surge. If anything – what really concerns me at this stage is a second surge, as I think about how the pandemic may play out over the next few weeks,” said Prof Karim. 

He also referred to countries such as the US, Spain, New Zealand, Vietnam, and South Korea, which are now facing a second surge. 

“We need to be very careful; this is not the time for complacency. We need to maintain all our efforts. If we look at one of the key drivers, it is the need for our economy to restart. We need to get people back to work,” said Prof Karim. 
According to him, we have to look at COVID-19 not as a sprint, but as a marathon. “As we learn to co-exist with this virus, aim for containment; we need to plan for the long term. Even if we get a vaccine, it is unlikely that we will be able to vaccinate a substantial part of our population before the end of next year.” 

“We need to transition from being scared to a situation where we can control our risk. When we know that we can control the risk and then influence the risk, we influence the risk of everyone around us. Part of the new normal is the strategy of mitigation with prevention, plus preventing outbreaks.”

Schools and vaccine development
Prof Gray spoke about whether schools should be open and the role that children play in transmission, how to avoid the second wave, how to adjust our testing, and the exciting news around vaccine development. 

As a paediatrician and a parent, Prof Gray said she believes schools should open. “Children have a different immune response to COVID-19. They have different immune responses to Coronavirus and they probably have less viral-load copies which makes them have milder diseases. They are lucky to have been spared from symptomatic or severe disease,” said Prof Gray. 

According to her, schools need to be de-risked as much as possible, with children and teachers wearing masks, washing hands, making sure that there is good ventilation in the school and that windows are wide open. 

“We also need to know about the comorbidity and ages of teachers, so that we can keep the sick and older teachers out of direct contact. The younger teachers with no comorbidities should be teaching. 

“We also know from our experiences with health workers that transmissions happen in the tearoom where teachers take off their masks and talk. We need to minimise the transmissions in tearooms and protect teachers and parents who are older and have comorbidities.”  

Prof Gray said from data she has seen, schools play a very small role in the transmission of COVID-19; a lot more (transmissions) happen in the community, by commuting, and overcrowded taxis.

Prof Gray agreed with Prof Karim that we should be concerned about a second wave, and that we need to make sure community transmissions are minimised. 

Regarding a vaccine, Prof Gray said a global race is on to find a vaccine. “The more vaccines the better, we want more vaccines to work. The more vaccines, the more affordable they are, and the more doses are available.”

One health approach

During her presentation, Prof Burt said the current response to outbreaks is largely reactive rather than proactive, and “if we have more of a one-health approach, with forecasting, early detection, and a more rapid response, we could have an impact on public health in the future”. 


News Archive

Her mission: Looking for viruses
2017-10-03

Description: Burt readmore Tags: Prof Felicity Burt, Felicity Burt, inaugural lecture, medical virology, UFS Faculty of Health Sciences, arboviruses 

Prof Felicity Burt delivering her inaugural lecture,
Catching a Virus
Photo: Stephen Collett

“Preparing and presenting an inaugural lecture is an opportunity to look back at one’s career and to enjoy previous highlights and achievements; to share these, not only with colleagues, but also with family and friends.”

This is according to Prof Felicity Burt, who recently presented her inaugural lecture, Catching a Virus. Prof Burt is a professor in medical virology in the Faculty of Health Sciences at the University of the Free State (UFS). It may sound ominous, but it is a story about identifying viruses, and finding and stopping them in their tracks in nature.

Research focus on arbo- and zoonotic viruses 
“My research focuses on arboviruses and zoonotic viruses,” said Prof Burt. “Arboviruses are viruses that are transmitted by insect vectors, such as mosquitoes, ticks, midges or sandflies, whereas zoonotic viruses are naturally transmitted from animals to humans. However, there is a considerable overlap between these two groups.” The research looks at host responses, virus discovery and surveillance in order to identify which of the viruses in circulation have the potential to cause human diseases.

“Emerging and re-emerging viruses have significant implications for public health,” said Prof Burt at the start of her lecture. She also stated that there have been disease outbreaks of unprecedented magnitude, which have spread and established in distinct geographic regions. “Many of these emerging viruses are transmitted by vectors or are spread to humans from animals. These viruses can cause significant diseases in humans,” said Prof Burt. 

There are many reasons why these viruses re-emerge, such as global warming, human invasion in forested areas, changes in agricultural practices, international travel, as well as the illegal movement of animals. Prof Burt used the Zika virus as an example of a recent emerging virus. 

More than 20 years’ experience 

With more than 20 years’ experience and a PhD in medical virology from the University of the Witwatersrand, Prof Burt is a renowned specialist. She has worked in the Special Pathogens Unit at the National Institute for Communicable Diseases, and was a member of various teams responding to outbreaks of Ebola and Rift Valley fever in Africa and Saudi Arabia, respectively. She is co-author of more than 51 articles in international scientific journals, as well as six chapters on arboviruses. In 2016, she was awarded a SARChl research chair by the South African Research Chair Initiative for her research on vector-borne and zoonotic diseases.

Click here to read the full lecture.

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