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31 August 2020 | Story Dr Chitja Twala
R Chitja Twala
Dr Chitja Twala is the Vice Dean in the Faculty of The Humanities.

In the 1940s, the then (Orange) Free State produced a crop of female leaders whose role in the liberation struggle is unknown – or rather, for whatever reason – ‘neglected’. Among these leaders was one Moipone Martha Motlhakwana. Testimony to the above was an article published by the Mail and Guardian on 25 August 2016 under the heading 60 Iconic Women – The people behind the 1956 Women’s March to Pretoria. In this article, only four lines are dedicated to her, contrary to what has been written about other leaders, such as Lilian Ngoyi, Lizzy Abrahams, Lucy Mvubelo, and many others. This is an indication of the possible ‘neglect’ in highlighting the role played by other women in places such as the Free State. In this article, I argue that Motlhakwana’s role in the liberation struggle was by no means minimal, compared to the leaders mentioned above. 

When one evaluates her role and contribution to the struggle, it is important to always keep in mind the context of the time and the scope of possibilities that were available to the liberation movements. This article briefly examines her role at a crucial time when Motlhakwana’s beloved movement, the African National Congress (ANC), is experiencing its most difficult and trying times since coming to power in 1994.

The Defiance Campaign

Motlhakwana was born into the Makabane family in Leqwala in the Thaba Nchu district on 23 December 1906. She was a devoted Christian. Being a Christian did not prevent her from participating fully in politics. Long before the 1956 anti-pass march, Motlhakwana was instrumental in organising the 1952 Defiance Campaign in Bloemfontein. Meetings for organising this campaign were held in an open space where the Paradise Hall in Bochabela Location in Bloemfontein is situated today. She led a women’s support group demanding the release of those arrested and jailed in the Ramkraal Prison in Bloemfontein. It became known to the Special Branch that her house was, at the time, used as the ANCWL’s ‘headquarters’ in town; therefore, the house was monitored and kept under police surveillance.

Motlhakwana also participated in the 1956 anti-mass march to Pretoria. In the Bloemfontein area, she mobilised people in the burning of passes. Her fearless organising strategies earned her a nickname in the community as Motabola Pasa or Mochesa Pasa (the one instrumental in tearing of the dompas or the one burning the passes). She was among the people who were arrested and detained during the Treason Trial. After being acquitted, she was placed under house arrest. Together with her friend in the struggle, Pretty Molatole, they were involved in establishing the ANCWL in Bloemfontein. Most of the league’s meetings were held at Motlhakwana’s place. She used to travel around the province to establish ANCWL branches in places such as Bethlehem, Ficksburg, and Thaba Nchu, to name a few. It was during this period in the mid-1950s that she worked closely with the leaders of the ANC in Bloemfontein, such as Jacob B Mafora, Caleb Motshabi, and Leslie Monnenyane.

In her honour

In honour of her contribution to the liberation struggle in South Africa and not only in the Free State, a tombstone was unveiled at the Phahameng Cemetery, adjacent to the Heroes’ Acre, on Thursday 5 January 2012; this unveiling coincided with the centenary celebrations of the ANC as the oldest liberation movement in Africa. Addressing the masses during the unveiling of the tombstone, the Chairperson of the ANCWL in the Free State and the current Premier, Sisi Ntombela, stated: “Most people have the concept that the anti-pass march started in Johannesburg in 1956, but that is not the case because the first march was started in the province by women such as Motlhakwana and Mei Likotsi and others who were leaders at the time, and mobilised the women for the march. As we unveiled the Motlhakwana tombstone, we also discovered that her grandchildren have kept the passes of those women whom she organised at that time. She made sure that women were developed, not only in politics but also in trade unionism. The Free State is the centre where everything started; this year [2012] is the ANC Centenary, but next year we will be holding the ANCWL Centenary for the Free State women.”

Owing to illness, Motlhakwana passed away on Thursday 27 July 1989. She was buried in the Phahameng ‘Magengenene’ Cemetery in Bloemfontein, not far from the Heroes’ Acre.

There are many women of Motlhakwana’s political stature in the Free State, whose histories should be documented in the form of biographies.

News Archive

Research contributes to improving quality of life for cancer patients
2016-11-21

Description: Inorganic Chemistry supervisors  Tags: Inorganic Chemistry supervisors

Inorganic Chemistry supervisors in the Radiopharmacy
Laboratory during the preparation of a typical complex
mixture to see how fast it reacts. Here are, from the left,
front: Dr Marietjie Schutte-Smith, Dr Alice Brink
(both scholars from the UFS Prestige
Scholar Programme), and Dr Truidie Venter (all three
are Thuthuka-funded researchers).
Back: Prof André Roodt and Dr Johan Venter.
Photo: Supplied

Imagine that you have been diagnosed with bone cancer and only have six months to live. You are in a wheelchair because the pain in your legs is so immense that you can’t walk anymore – similar to a mechanism eating your bones from the inside.

You are lucky though, since you could be injected with a drug to control the pain so effective that you will be able to get out of the wheelchair within a day-and-a-half and be able to walk again. Real-life incidents like these provide intense job satisfaction to Prof André Roodt, Head of Inorganic Chemistry at the University of the Free State (UFS). The research, which is conducted by the Inorganic Group at the UFS, contributes greatly to the availability of pain therapy that does not involve drugs, but improves the quality of life for cancer patients.

The research conducted by the Inorganic Group under the leadership of Prof Roodt, plays a major role in the clever design of model medicines to better detect and treat cancer.

The Department of Chemistry is one of approximately 10 institutions worldwide that conducts research on chemical mechanisms to identify and control cancer. “The fact that we are able to cooperate with the Departments of Nuclear Medicine and Medical Physics at the UFS, the Animal Research Centre, and other collaborators in South Africa and abroad, but especially the methodology we utilise to conduct research (studying the chemical manner in which drugs are absorbed in cancer as well as the time involved), enhances the possibility of making a contribution to cancer research,” says Prof Roodt.

Technique to detect cancer spots on bone
According to the professor, there are various ways of detecting cancer in the body. Cancer can, inter alia, be identified by analysing blood, X-rays (external) or through an internal technique where the patient is injected with a radioactive isotope.

Prof Roodt explains: “The doctor suspects that the patient has bone cancer and injects the person with a drug consisting of an isotope (only emits X-rays and does no damage to tissue) that is connected to a phosphonate (similar to those used for osteoporosis). Once the drug is injected, the isotope (Technetium-99m) moves to the spot on the bone where the cancer is located. The gamma rays in the isotope illuminate the area and the doctor can see exactly where treatment should be applied. The Technetium-99m has the same intensity gamma rays as normal X-rays and therefore operates the same as an internal X-ray supply.” With this technique, the doctor can see where the cancer spots are within a few hours.

The same technique can be used to identify inactive parts of the brain in Alzheimer patients, as well as areas of the heart where there is no blood supply or where the heart muscle is dead.

Therapeutic irradiation of cancer
For the treatment of pain connected with cancer, the isotope Rhenium-186 is injected. Similar to the manner in which the Technetium-99m phosphonate compound is ingested into the body, the Rhenium-186 phosphonate travels to the cancer spots. Patients thus receive therapeutic irradiation – a technique known as palliative therapy, which is excellent for treating pain. A dosage of this therapy usually lasts for about two months.

The therapy is, however, patient specific. The dosages should correspond with the occurrence and size of cancer spots in the patient’s body. First, the location of the cancer will be determined by means of a technetium scan. After that, the size of the area where the cancer occurs has to be determined. The dosage for addressing total pain distribution will be calculated according to these results.

Technique to detect cancer spots on soft tissue
Another technique to detect cancer as spots on bone or in soft tissue and organs throughout the body is by utilising a different type of irradiation, a so-called PET isotope. The Fluor-18 isotope is currently used widely, and in Pretoria a machine called a cyclotron was produced by Dr Gerdus Kemp, who is a former PhD graduate from the Inorganic Research Group. The F-18 is then hidden within a glucose molecule and a patient will be injected with the drug after being tranquillised and after the metabolism has been lowered considerably. The glucose, which is the ‘food' that cancer needs to grow, will then travel directly to the cancer area and the specific area where the cancer is located will thus be traced and ‘illuminated’ by the Fluor-18, which emits its own 'X-rays'.

In the late 80s, Prof Roodt did his own postdoctoral study on this research in the US. He started collaborating with the Department of Nuclear Medicine at the UFS in the early 90s, when he initiated testing for this research.

Through their research of more than 15 years, the Inorganic Group in the Department of Chemistry has made a major contribution to cancer research. Research on mechanisms for the detection of cancer, by designing new clever chemical agents, and the chemical ways in which these agents are taken up in the body, especially contributes to the development in terms of cancer therapy and imaging, and has been used by a number of hospitals in South Africa.

The future holds great promise
Prof Roodt and his team are already working on a bilateral study between the UFS and Kenya. It involves the linking of radio isotopes, as mentioned above, to known natural products (such as rooibos tea), which possess anti-cancer qualities.

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