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20 August 2020 | Story Andre Damons | Photo Barend Nagel
Prof Motlalepula Matsabisa, Associate Professor in the Department of Pharmacology at the University of the Free State (UFS), has been appointed as the chairperson of the World Health Organisation’s (WHO) Regional Expert Advisory Committee on Traditional Medicines for COVID-19.

Prof Motlalepula Matsabisa, Associate Professor in the Department of Pharmacology at the University of the Free State (UFS), will lead Africa’s fight against the COVID-19 pandemic with his appointment as chairperson of the World Health Organisation’s (WHO) Regional Expert Advisory Committee on Traditional Medicines for COVID-19.

Prof Matsabisa has been chosen over 25 other experts from 27 African countries to head this expert committee tasked with setting up research and clinical trials for COVID-19 and beyond. The committee is also supported by the African Union (AU), the Centers for Disease Control and Prevention (CDC – Africa), and the European and Developing Countries Clinical Trials Partnership (EDCTP).

This committee was established by the WHO and the Africa CDC on 22 July with the aim of providing independent scientific advice and support to countries on the safety, efficacy, and quality of traditional medicine therapies. It is also an effort to enhance research and development of traditional medicines for COVID-19 in Africa.

Looking forward

“This is a huge continental and global responsibility being laid on my shoulders as a chairperson.  I have to keep the committee together and ensure that it delivers on its set mandate and terms of reference.  I need to ensure that the committee helps the continent and region to get the scientific and legislative aspects on traditional medicine development on track.”  

“I have taken this position and responsibility, knowing quite well what it entails. I want to do this for the continent and for the sake of good science of all traditional healers and consumers of traditional medicines on the continent and beyond,” says Prof Matsabisa.

According to Prof Matsabisa, he is looking forward to working with a team of dedicated experts from 27 countries in the African region, and being of help to countries that need assistance with clinical trials, including preclinical work to move to clinical research.

Prof Matsabisa says he is also looking forward to countries asking South Africa to be part of their multi-centre studies in clinical trials for traditional medicines, and to help set up clinical trial teams that include Western-trained clinicians to get into traditional medicine studies. 

The work of the committee

According to Prof Matsabisa, his new position took effect the same day as his appointment and will run as long as COVID-19 is part of our daily lives and even beyond. It entails supporting member states to implement the WHO master plan for clinical trial protocols in order to generate credible data for COVID-19 results, based on traditional medicines. The committee will also coordinate support to member states in the African region to collaborate on clinical trials of traditional medicine-based therapies – elevating standards by pooling expertise in multicentre studies, as well as complying with GCP and good participatory practice guidelines for trials of emerging and re-emerging pathogens.
“The committee will also advise on strengthening the capacity of national medicine regulatory authorities to accelerate the issuance of marketing authorisations for traditional medicine products that have been well researched for safety, efficacy, and quality, as well as to expedite the approval of clinical trials on traditional medicines. This will help to meet the national registration criteria and the WHO norms and standards of quality, safety, and efficacy for the management of COVID-19 and others.”

“It will also provide independent scientific advice to the WHO and other partners regarding policies, strategies, and plans for integrating traditional medicines into COVID-19 responses and health systems,” explains Prof Matsabisa. 

Aiming for the top spot 

Prof Matsabisa has been described as having the third highest research output – something he is not satisfied with. 
“I was disappointed that only one point separated me from the second place. I will push for first place as this is my ultimate aim. My motivation for this is simple – I like what I am doing, I do not take it as a job but do it because I love research.”  

“I always like to tell students that we should be proud to one day see products in the shops that we can relate to and to which we have contributed or that we have made.   This is what drives me and my staff.  I have a beautiful team of students, staff, and postdoctoral fellows who share my vision of research.  We all have a shared vision and strive to be relevant at all times in science research, development, and teaching.”

• Prof Matsabisa was recently part of a national conference with the theme: Harnessing science, technology, and innovation in response to COVID-19: A national and international effort. The conference was hosted by Dr Blade Nzimande, Minister of Higher Education, Science and Innovation, with Pres Cyril Ramaphosa, Dr Zweli Mkhize, Minister of Health, Ebrahim Patel, Minister of Trade, Industry and Competition, Prof Sarah Anyang Agbor, African Union Commissioner for Human Resources, Science and Technology, and Dr Tedros Adhanom Ghebreyesus, Director-General of the World Health Organisation, in attendance. 

News Archive

Plant eco-physiologist finds effective solutions for crop optimisation
2016-07-24

Description: Orange trees Tags: Orange trees

The bio-stimulant was tested on
this citrus. This is the first time
that the product has been tested
on a crop.

In a time characterised by society facing increasing population growth, food crises, and extreme climatic conditions such as drought, it is essential for farmers to integrate science with their work practices in order to optimise crops.

Role of photosynthesis and plant sap data

By knowing how to use photosynthesis and plant sap data for determining plant health, fast and effective solutions could be established for the optimisation of crops. This technique, which could help farmers utilise every bit of usable land effectively, is the focus of Marguerite Westcott’s PhD study. She is a junior lecturer and plant eco-physiologist in die Department of Plant Sciences at the University of the Free State.

Westcott uses this technique in her studies to prove that a newly-developed bio-stimulant stimulates plants in order to metabolise water and other nutrients better, yielding increased crops as a result.

Agricultural and mining sectors benefit from research

The greatest part of these projects focuses on the agricultural sector. Westcott and a colleague, Dr Gert Marais, are researching the physiology of pecan and citrus trees in order to optimise the growth of these crops, thus minimising disease through biological methods. Field trials are being conducted in actively-producing orchards in the Hartswater and Patensie areas in conjunction with the South African Pecan Nut Producers Association (SAPPA) amongst others.
 
The principles that Westcott applies in her research are also used in combination with the bio-stimulant in other studies on disturbed soil, such as mine-dump material, for establishing plants in areas where they would not grow normally. This is an economical way for both the agricultural and mining sectors to improve nutrient absorption, stimulate growth, and contribute to the sustainable utilisation of the soil.

Description: Pecan nut orchards  Tags: Pecan nut orchards

The bio-stimulant contributes to the immunity of the plants.
It was tested in these pecan nut orchards (Hartswater).

Soil rehabilitation key aspect in research projects

“One of two things is happening in my research projects. Either the soil is rehabilitated to bring about the optimal growth of a plant, or the plants are used to rehabilitate the soil,” says Westcott.

Data surveys for her PhD studies began in 2015. “This will be a long-term project in which seasonal data will be collected continuously. The first set of complete field data, together with pot trial data, will be completed after the current crop harvest,” says Westcott.

 

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