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20 August 2020 | Story Andre Damons | Photo Barend Nagel
Prof Motlalepula Matsabisa, Associate Professor in the Department of Pharmacology at the University of the Free State (UFS), has been appointed as the chairperson of the World Health Organisation’s (WHO) Regional Expert Advisory Committee on Traditional Medicines for COVID-19.

Prof Motlalepula Matsabisa, Associate Professor in the Department of Pharmacology at the University of the Free State (UFS), will lead Africa’s fight against the COVID-19 pandemic with his appointment as chairperson of the World Health Organisation’s (WHO) Regional Expert Advisory Committee on Traditional Medicines for COVID-19.

Prof Matsabisa has been chosen over 25 other experts from 27 African countries to head this expert committee tasked with setting up research and clinical trials for COVID-19 and beyond. The committee is also supported by the African Union (AU), the Centers for Disease Control and Prevention (CDC – Africa), and the European and Developing Countries Clinical Trials Partnership (EDCTP).

This committee was established by the WHO and the Africa CDC on 22 July with the aim of providing independent scientific advice and support to countries on the safety, efficacy, and quality of traditional medicine therapies. It is also an effort to enhance research and development of traditional medicines for COVID-19 in Africa.

Looking forward

“This is a huge continental and global responsibility being laid on my shoulders as a chairperson.  I have to keep the committee together and ensure that it delivers on its set mandate and terms of reference.  I need to ensure that the committee helps the continent and region to get the scientific and legislative aspects on traditional medicine development on track.”  

“I have taken this position and responsibility, knowing quite well what it entails. I want to do this for the continent and for the sake of good science of all traditional healers and consumers of traditional medicines on the continent and beyond,” says Prof Matsabisa.

According to Prof Matsabisa, he is looking forward to working with a team of dedicated experts from 27 countries in the African region, and being of help to countries that need assistance with clinical trials, including preclinical work to move to clinical research.

Prof Matsabisa says he is also looking forward to countries asking South Africa to be part of their multi-centre studies in clinical trials for traditional medicines, and to help set up clinical trial teams that include Western-trained clinicians to get into traditional medicine studies. 

The work of the committee

According to Prof Matsabisa, his new position took effect the same day as his appointment and will run as long as COVID-19 is part of our daily lives and even beyond. It entails supporting member states to implement the WHO master plan for clinical trial protocols in order to generate credible data for COVID-19 results, based on traditional medicines. The committee will also coordinate support to member states in the African region to collaborate on clinical trials of traditional medicine-based therapies – elevating standards by pooling expertise in multicentre studies, as well as complying with GCP and good participatory practice guidelines for trials of emerging and re-emerging pathogens.
“The committee will also advise on strengthening the capacity of national medicine regulatory authorities to accelerate the issuance of marketing authorisations for traditional medicine products that have been well researched for safety, efficacy, and quality, as well as to expedite the approval of clinical trials on traditional medicines. This will help to meet the national registration criteria and the WHO norms and standards of quality, safety, and efficacy for the management of COVID-19 and others.”

“It will also provide independent scientific advice to the WHO and other partners regarding policies, strategies, and plans for integrating traditional medicines into COVID-19 responses and health systems,” explains Prof Matsabisa. 

Aiming for the top spot 

Prof Matsabisa has been described as having the third highest research output – something he is not satisfied with. 
“I was disappointed that only one point separated me from the second place. I will push for first place as this is my ultimate aim. My motivation for this is simple – I like what I am doing, I do not take it as a job but do it because I love research.”  

“I always like to tell students that we should be proud to one day see products in the shops that we can relate to and to which we have contributed or that we have made.   This is what drives me and my staff.  I have a beautiful team of students, staff, and postdoctoral fellows who share my vision of research.  We all have a shared vision and strive to be relevant at all times in science research, development, and teaching.”

• Prof Matsabisa was recently part of a national conference with the theme: Harnessing science, technology, and innovation in response to COVID-19: A national and international effort. The conference was hosted by Dr Blade Nzimande, Minister of Higher Education, Science and Innovation, with Pres Cyril Ramaphosa, Dr Zweli Mkhize, Minister of Health, Ebrahim Patel, Minister of Trade, Industry and Competition, Prof Sarah Anyang Agbor, African Union Commissioner for Human Resources, Science and Technology, and Dr Tedros Adhanom Ghebreyesus, Director-General of the World Health Organisation, in attendance. 

News Archive

Chemistry research group receives international recognition
2016-10-28

Description: Chemistry research group  Tags: Chemistry research group

Dr Carla Pretorius mounts microcrystals with
Dumisani Kama while Pennie Mokolokolo
observe the technique.
Photo: Supplied


Crystals and crystallography form an integrated part of our daily lives, from bones and teeth, to medicines and viruses, new catalysts, jewellery, colour pigments, chocolates, analysing rocks on the moon and Mars, electronics, batteries, metal blades in airplane turbines, panels for solar energy and many more.

In spite of this, not many people know much about X-ray crystallography, although it is probably one of the greatest innovations of the 20th century, spanning the sciences. That is why this discipline is actively researched by a number of tertiary institutions around the globe as well as the Inorganic Chemistry Group of the Department of Chemistry at the University of the Free State (UFS).

Research by the Inorganic Chemistry Group includes:
•    clever design of model medicines to better detect cancer and study heart, bone and brain defects;
•    production of new compounds for making new and better automobile fuels and decrease carbon dioxide in the atmosphere;
•    generation and purification of new South African mineral resources for metals widely used in turbines which use wind energy.

A group of UFS students have received acknowledgement for their research at six international venues in the past few months.

Posters in Cameroon
Twelve postgraduate students, together with Prof André Roodt, Head of the Inorganic Chemistry division at the UFS, delivered three oral presentations, nine posters, one plenary and one keynote lecture abroad.

Four UFS students - Nina Morogoa, Pheello Nkoe, Alebel Bilay, and Mohammed Elmakki - who delivered posters at the First Pan African Conference on Crystallography in Dschang, Cameroon, received prizes for their presentations.

School and conference in Croatia

Students Orbett Alexander and Dumisani Kama were selected to attend the intense and demanding Third European Crystallographic School in Bôl, Croatia. Both Kama, Alexander and Prof Roodt gave oral presentations at the 24th Croatian-Slovenian Crystallographic Meeting at Brac Island, Croatia.

Kama, together with Dr Ferdi Groenewald, Dr Carla Pretorius and Pennie Mokolokolo, also attended the European Synchrotron Radiation Facility (ESRF) in Grenoble, France. The ESRF is a centre of excellence for fundamental and innovation-driven research. The storage ring at this laser facility can generate X-rays 100 billion times brighter than typical medical and laboratory X-ray sources.

Research in Switzerland

Kama and Mokolokolo also spent one month on research visits at the University of Zurich in Switzerland. Both Kama and Alexander were invited to present their research orally to the Institute of Inorganic Chemistry in Zurich, headed by Prof Roger Alberto.

In Basel, Switzerland, Dr Ferdi Groenewald, Dr Renier Koen, and Dr Truidie Venter all presented their research at the 30th European Crystallographic Meeting.

Prof Roodt said: “It is incredibly important that our postgraduate students get the chance to interact, discuss, and be taught by the best in the world and realise that hard work on basic and applied chemistry processes leads to broader recognition. The delegates to these international venues came from more than 60 countries and took note of our students work. With these young researchers, our future at the UFS and at Inorganic Chemistry is in good hands”.

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