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20 August 2020 | Story Andre Damons | Photo Barend Nagel
Prof Motlalepula Matsabisa, Associate Professor in the Department of Pharmacology at the University of the Free State (UFS), has been appointed as the chairperson of the World Health Organisation’s (WHO) Regional Expert Advisory Committee on Traditional Medicines for COVID-19.

Prof Motlalepula Matsabisa, Associate Professor in the Department of Pharmacology at the University of the Free State (UFS), will lead Africa’s fight against the COVID-19 pandemic with his appointment as chairperson of the World Health Organisation’s (WHO) Regional Expert Advisory Committee on Traditional Medicines for COVID-19.

Prof Matsabisa has been chosen over 25 other experts from 27 African countries to head this expert committee tasked with setting up research and clinical trials for COVID-19 and beyond. The committee is also supported by the African Union (AU), the Centers for Disease Control and Prevention (CDC – Africa), and the European and Developing Countries Clinical Trials Partnership (EDCTP).

This committee was established by the WHO and the Africa CDC on 22 July with the aim of providing independent scientific advice and support to countries on the safety, efficacy, and quality of traditional medicine therapies. It is also an effort to enhance research and development of traditional medicines for COVID-19 in Africa.

Looking forward

“This is a huge continental and global responsibility being laid on my shoulders as a chairperson.  I have to keep the committee together and ensure that it delivers on its set mandate and terms of reference.  I need to ensure that the committee helps the continent and region to get the scientific and legislative aspects on traditional medicine development on track.”  

“I have taken this position and responsibility, knowing quite well what it entails. I want to do this for the continent and for the sake of good science of all traditional healers and consumers of traditional medicines on the continent and beyond,” says Prof Matsabisa.

According to Prof Matsabisa, he is looking forward to working with a team of dedicated experts from 27 countries in the African region, and being of help to countries that need assistance with clinical trials, including preclinical work to move to clinical research.

Prof Matsabisa says he is also looking forward to countries asking South Africa to be part of their multi-centre studies in clinical trials for traditional medicines, and to help set up clinical trial teams that include Western-trained clinicians to get into traditional medicine studies. 

The work of the committee

According to Prof Matsabisa, his new position took effect the same day as his appointment and will run as long as COVID-19 is part of our daily lives and even beyond. It entails supporting member states to implement the WHO master plan for clinical trial protocols in order to generate credible data for COVID-19 results, based on traditional medicines. The committee will also coordinate support to member states in the African region to collaborate on clinical trials of traditional medicine-based therapies – elevating standards by pooling expertise in multicentre studies, as well as complying with GCP and good participatory practice guidelines for trials of emerging and re-emerging pathogens.
“The committee will also advise on strengthening the capacity of national medicine regulatory authorities to accelerate the issuance of marketing authorisations for traditional medicine products that have been well researched for safety, efficacy, and quality, as well as to expedite the approval of clinical trials on traditional medicines. This will help to meet the national registration criteria and the WHO norms and standards of quality, safety, and efficacy for the management of COVID-19 and others.”

“It will also provide independent scientific advice to the WHO and other partners regarding policies, strategies, and plans for integrating traditional medicines into COVID-19 responses and health systems,” explains Prof Matsabisa. 

Aiming for the top spot 

Prof Matsabisa has been described as having the third highest research output – something he is not satisfied with. 
“I was disappointed that only one point separated me from the second place. I will push for first place as this is my ultimate aim. My motivation for this is simple – I like what I am doing, I do not take it as a job but do it because I love research.”  

“I always like to tell students that we should be proud to one day see products in the shops that we can relate to and to which we have contributed or that we have made.   This is what drives me and my staff.  I have a beautiful team of students, staff, and postdoctoral fellows who share my vision of research.  We all have a shared vision and strive to be relevant at all times in science research, development, and teaching.”

• Prof Matsabisa was recently part of a national conference with the theme: Harnessing science, technology, and innovation in response to COVID-19: A national and international effort. The conference was hosted by Dr Blade Nzimande, Minister of Higher Education, Science and Innovation, with Pres Cyril Ramaphosa, Dr Zweli Mkhize, Minister of Health, Ebrahim Patel, Minister of Trade, Industry and Competition, Prof Sarah Anyang Agbor, African Union Commissioner for Human Resources, Science and Technology, and Dr Tedros Adhanom Ghebreyesus, Director-General of the World Health Organisation, in attendance. 

News Archive

Research helps farmers save with irrigation
2017-02-15

Description: Irrigation research Tags: Irrigation research

Marcill Venter, lecturer in the Department of
Agricultural Economics at the University of the
Free State, has developed the mathematical
programming system, Soil Water Irrigation
Planning and Energy Management in order to
determine irrigation pump hours.
Photo: Rulanzen Martin

Her advice to farmers is that they should make sure they are aware of the total cost (investment and operating costs) of an irrigation system. In most cases the investment cost is low, but the operating cost over the lifetime of the system is high.

“It is very important to have a look at the total cost and to install the most economic system,” says Marcill Venter, lecturer at the University of the Free State (UFS), who has done research on the economic sustainability of water-pipe systems.

Irrigation systems important components for farming
This research comes at a time when many farmers are relying on their irrigation systems due to persistent drought and low rainfall during 2016. South Africa has also experienced an abnormal increase in electricity tariffs in recent years. Due to tariff increases which threaten the future profitability of irrigation producers, the Water Research Commission (WRC) has launched and financed a project on the sustainable management of irrigation farming systems. “I had the opportunity to work on the project as a researcher,” says Venter.

The heart of every irrigation system is the water pipes that bring life to crops and livestock, and this is what Venter’s research is about. “Water pipes are part of the whole design of irrigation systems. The design of the system impact certain factors which determine the investment and operating costs,” she says.

Mathematical system to help farmers
Venter and Professor Bennie Grové, also from the Department of Agricultural Economics at the UFS, designed the Soil Water Irrigation Planning and Energy Management (SWIP-E) programming model as part of the WRC’s project, as well as for her master’s degree. “The model determines irrigation pump hours through a daily groundwater budget, while also taking into account the time-of-use electricity tariff structure and change in kilowatt requirements arising from the main-line design,” says Venter. The model is a non-linear programming model programmed in General Algebraic Modeling System (GAMS).

Design of irrigation system important for sustainability

The main outcome of the study is that the time-of-use electricity tariff structure (Ruraflex) is always more profitable than the flat-rate structure (Landrate). The interaction between the management and design of a system is crucial, as it determines the investment and operating costs. Irrigation designers should take the investment and operating cost of a system into account during the design process. The standards set by the South African Irrigation Institute (SAII) should also be controlled and revised.

Water-pipe thickness plays major role in cost cuts
There is interaction between water-pipe thickness, investment and operating costs. When thinner water pipes are installed, it increases the friction in the system as well as the kilowatt usage. A high kilowatt increases the operating cost, but the use of thinner water pipes lowers the investment cost. Thicker water pipes therefore lower the friction and the kilowatt requirements, which leads to lower operating costs, but thicker pipes have a higher investment cost. “It is thus crucial to look at the total cost (operating and investment cost) when investing in a new system. Farmers should invest in the system with the lowest total cost,” says Venter.

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