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28 December 2020 | Story André Damons | Photo Supplied
Dr Michael Pienaar is a lecturer in the University of the Free State’s (UFS) department of Paediatrics and Child Health.

A lecturer from the University of the Free State’s (UFS) department of Paediatrics and Child Health is investigating the use of artificial neural networks to develop models for the prediction of patient outcomes in children with severe illness.

Dr Michael Pienaar, senior lecturer and specialist, is conducting this research as part of his doctoral research and the study deals primarily with the development of models that are designed and calibrated for use in South Africa. These artificial neural networks are computer programs designed to mimic some of the learning characteristics of biological neurons.

The potential applications of models

According to Dr Pienaar these models have traditionally been developed in high-income nations using conventional statistical methods.

“The potential applications of such models in the clinical setting include triage, medical research, guidance of resource allocation and quality control. Having initially begun this research investigating the prediction of mortality outcomes in the paediatric intensive care unit (PICU) I have broadened my scope to patients outside of PICU, seeking to identify children early during their illnesses who are at risk of serious illness requiring PICU,” says Dr Pienaar.

The research up until now has been directed towards the identification of characteristics that are both unique to children with serious illness in South Africa, but also accessible to clinicians in settings where expertise and technical resources are limited.

Research still in the early changes

The research is still in its early stages but next year a series of expert review panels will be held to investigate the selection of variables for the model, after which the collection of clinical data will begin. Once the data has been collected and prepared, a number of candidate models will be developed and evaluated. This should be concluded by the end of 2022.

Says Dr Pienaar: “The need to engage with the rapid proliferation of technology, particularly in the realms of machine learning, mobile technology, automation and the Internet of Things is as great in medical research now as it is in any academic discipline.

“It is critical that research, particularly in South Africa, engage with this in order to take advantage of the opportunities offered and avoid the dangers that go paired with them. Together with the technology as such, it has been essential to pursue this project as an interdisciplinary undertaking involving clinicians, biostatisticians and computer engineers.”

Hope for the research  

Dr Pienaar says he was very fortunate and grateful to be the recipient of a generous interdisciplinary grant from the UFS which has allowed him to procure software and equipment that is critical to this project.

“The hope for this research is that the best performing of these models can be integrated with a mobile application that assists practitioners in a wide range of settings in the identification, treatment and early referral of children at high risk of severe illness. I would like to expand this research project to include other countries in Africa and South America and to use it as a bridge to collaboration with other clinical researchers in the Global South,” says Dr Pienaar.

As an early career researcher, Dr Pienaar hopes that this research can serve as a platform to build a body of research that uses the rapid technological advances of these times together with a wide range of collaborations with other disciplines in the pursuit of better child health.

He concludes by saying that he has had excellent support thus far from his supervisors, Prof Stephen Brown (Faculty of Health Sciences, UFS), Dr Nicolaas Luwes (Faculty of Computer Science and Engineering, Central University of Technology) and Dr Elizabeth George (Medical Research Council Clinical Trials Unit, University College London). I have also been supported by the Robert Frater Institute in the Faculty of Health Sciences.

News Archive

Incidents on the Bloemfontein Campus
2016-08-25

Statement by the Institutional Forum of the University of the Free State (UFS) - Released by Dr Willy Nel (Chairperson) on behalf of the Institutional Forum of the UFS

 

Two incidents happened on campus the past week, which were brought to the attention of the university management:

1. The university management received a complaint on 16 August 2016 that a student had sprayed liquid in the face of a security guard at one of the university gates. The reason appears to be that three students were sent back to their residence to collect their student cards in order to exit the campus – as required – and this might have caused the reaction. In video footage, it is clear that a student on the passenger side was responsible for the spraying incident. Statements have been taken from the three students in the car as well as from the affected security guard. The student claims that the liquid was water from his gym bottle. Regardless, charge sheets were prepared and delivered, and the disciplinary hearing has been scheduled on an urgent basis for 1 September 2016.

2. An incident happened on the Bloemfontein Campus on 23 August 2016, with a test being distributed in a class where the answer to one of the questions was included in the Afrikaans version, while it was excluded in the English version. The matter was investigated and it was decided that the written test will be set aside and a new test, covering the same scope, will be compiled for all students; the new test will be subject to external moderation; and external moderation of tests in the particular department will take place until the end of the year. The lecturer concerned claims that this was a genuine mistake and not intentional, in that guidelines for that one question were removed after a decision to add further examination questions, which made the guidelines obsolete; in the process of revising the papers, the lecturer made a mistake and did not remove the guidelines for both the English and Afrikaans versions. Nonetheless, the university management has decided on a disciplinary process involving the lecturer concerned, given the seriousness of the matter.


Released by:
Lacea Loader (Director: Communication and Brand Management)
Tel: +27 51 401 3422/2707 or +27 83 645 2454
Email: news@ufs.ac.za  | loaderl@ufs.ac.za
Fax: +27 51 444 6393


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