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08 December 2020 | Story Leonie Bolleurs | Photo Supplied
At the BJCP beer judging competition, Dr Errol Cason won Best of Show with his Belgian Saison. Here he is presenting at the AfricaBrew2020 Brewing conference.

Staff and students from the University of the Free State (UFS) once again proved their skills in beer homebrewing when they walked away with one first place and two second places at the 13th annual Anheuser-Busch Inbev (AB-Inbev) – formally South African Breweries (SAB) – intervarsity beer brewing and tasting competition, and the Beer Judging Certification Programme (BJCP) competition held at the AfricaBrew2020 Brewing conference. Both these events took place over the weekend of 27 and 28 November 2020.

Evil Twin Double and Three Sips German 

Competing in the AB-Inbev/SAB Intervarsity brewing and tasting competition, was a group of students from the UFS Department of Microbial, Biochemical and Food Biotechnology, consisting of Eduvan Bischoff (PhD student), Elzette van der Walt (MSc student), Culien van der Merwe (MSc student), Gunther Staats (MSc student), and Twyne Skein (MSc student). This team came second in both the Indian Pale Ale (IPA) category with their Evil Twin Double IPA and in the Lager category with their Three Sips German Pils. 

“This is an outstanding accomplishment. Congratulations also go to our fellow Free Stater’s at the Central University of Technology (CUT) for winning the India Pale Ale (IPA) category as well as best overall beer with their New England IPA,” commented Dr Errol Cason, Senior Lecturer in the UFS Department of Animal Science, also representing the liquid yeast company LiquidCulture Yeast.

According to Dr Cason, this SAB-sponsored competition sees students from local universities brew and enter beers for judging, and competing for prizes, including the coveted ‘Best of Show’ trophy. 

“This event also aims to promote beer culture along with responsible drinking, by hosting talks by industry experts where students can interact with commercial brewers, scientists, and marketers,” says Dr Cason. 

The event was hosted by South African Breweries (SAB) and CUT, through the Centre for Applied Food Sustainability and Biotechnology (CAFSaB), in association with the UFS. 

Although the event was moved online in 2020 due to the international pandemic, it did not mean that there was a decline in the quality of presentations, or in the beer entered by universities. – D r Errol Cason

Dr Cason explains that entrants are usually challenged to brew beers according to the 2015 Beer Judge Certification Programme (BJCP) guidelines in lager, IPA, winter warmer, and fruit beer categories. 

“This year included the African Premium Ale and Lockdown Brew categories as well, where teams were mostly left to invent and experiment on their own with a few rules, such as using only indigenous African ingredients or ingredients that were available in supermarkets during lockdown,” says Dr Cason. 

There is also an award for the best bottle dress (label). 

Dr Cason believes that although the event was moved online in 2020 due to the international pandemic, it did not mean that there was a decline in the quality of presentations, or in the beer entered by universities. 

Belgian Saison and Extra Special Bitter

He and Christopher Rothmann, who is busy with a PhD in Biotechnology at the UFS and is co-founder of the company LiquidCulture (LC) Yeast, attended and presented at the AfricaBrew2020 Brewing conference. AfricaBrew is an annual brewing conference specialising in workshops and demonstrations for home and professional brewers. 

Accompanying the conference is a BJCP beer judging competition where all home and professional brewers can enter beers. During this competition, Dr Cason won Best of Show with his Belgian Saison. Rothmann came second with his Extra Special Bitter.

Since LiquidCulture Yeast was found in 2018, this commercial venture has since spun out and are now providing liquid brewing yeast to the homebrewing and commercial brewing industry. Rothmann and Dr Cason are also founding members of the Kovsie Brewery (along with Dr Jan-G Vermeulen and Eduan Hellmuth), which is currently being constructed on the UFS Paradys Experimental Farm facility.

News Archive

Nuclear Medicine on the forefront of cancer research
2017-07-10

Description: Nuclear Medicine on the forefront of cancer research Tags: Nuclear Medicine, cancer research, Dr Je’nine Horn-Lodewyk’s, tumour detection method, cancer, Department of Nuclear Medicine 

Dr Je’nine Horn-Lodewyk’s tumour detection method
could be the cost-effective breakthrough needed to decrease
the mortality rate in breast cancer patients.
Photo: Anja Aucamp

The field of Nuclear Medicine in South Africa and the rest of the world are expanding rapidly due to the development of hybrid cameras and new radiopharmaceuticals. These developments have a huge impact on the diagnosis and therapy of cancer.

The most advanced of these cameras, Positron emission tomography combined with normal CTs (PETCT), are not yet widely available in South Africa due to the cost of the cameras and the radiopharmaceuticals. A more cost-effective alternative can be of great benefit. To achieve this, the focus should be on developing new radiopharmaceuticals that can be used with the current cost-effective gamma cameras, according to University of the Free State researcher, Dr Je’nine Horn-Lodewyk from the Department of Nuclear Medicine.

Fluorodeoxyglucose (18F-FDG), a radiolabelled glucose analogue, is currently the radiopharmaceutical most commonly used in PET/CT imaging for mainly oncology indications. Although it is considered the gold standard for imaging in several malignancies, it does have certain disadvantages. An 18F-FDG PET/CT diagnostic imaging study can cost between R25 000 and R35 000 for a single patient in the private sector. The 18F-FDG is also more radioactive, which requires much stricter handling and shielding to avoid high radiation dosages to staff and patients.

Successful research potential innovative solution
In the search for the ideal radiopharmaceutical for tumour detection, the South African National Nuclear Energy Corporation (Necsa) developed a local synthesis process for ethylenedicysteine-deoxyglucose (EC-DG). EC-DG is also a glucose analogue similar to FDG. They succeeded in labelling the compound with Technetium-99-metastable-pertechnetate (99mTcO4-), the most common nuclear medicine isotope used for approximately 95% of nuclear medicine procedures, creating 99mTc-EC-DG.

In partnership with Dr Horn-Lodewyk, this compound was successfully used in various animal models and clinical scenarios, resulting in approval by the Medicine Control Council to use it in a human study. Research is also planned in order to investigate diagnostic accuracy in other cancers like lymphoma.  The end result of this research can produce a radiopharmaceutical that is cost effective, does not require the use of costly specialised equipment, has no significant side-effects, no special patient preparation, renders late imaging possible, and has decreased radiation risks.

Dr Horn-Lodewyk is grateful for the support of her mentor, Prof Anton Otto, as well as Dr Gert Engelbrecht, Head of the Department of Nuclear Medicine, Prof Jan Rijn Zeevaart from North-West University’s Preclinical Drug Development Platform and Necsa, and Judith Wagener from Necsa. This innovative research would also not have been possible without the financial assistance of Dr Glen Taylor and Eleanor van der Westhuizen in the Directorate of Research Development.

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