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21 December 2020 | Story Rulanzen Martin | Photo Supplied
The children who took part in the 2020 music programme received a certificate for completing the project.

The yearly Heidedal music outreach progamme presented by the Odeion School of Music (OSM) and the Reach our Community Foundation (ROC) is growing from strength to strength each year. Amid the uncertainties of 2020 three students from the OSM persevered and vowed to continue with the teaching progamme to bring music by the community for the community. 

This annual outreach programme was founded by the Music department at the OSM in 2015 and forms part of the BMus, BA (Music) and Diploma in Music qualification which integrates Music education modules with service learning.

This year’s progamme was established as an alternative to the Marimba Project which has been running for five years. “The aim is to continue with the programme in years to come, equipping and empowering the students to continue with instrumental training,” said Nadia Smith, a BAMus honours student and programme leader. 

Students take charge of 2020 programme 

Nadia Smith, together with third-year BMus students Liana Bester, and Chrismari Grobler, who all voluntarily took part in the progamme for six weeks, presented music lessons to 11 children in Heidedal. “Apart from the music knowledge these children gained they learned about teamwork and collaboration. They gained confidence and self-assurance, and reaped the fruit of their hard work,” said Smith.  

For Smith the six weeks of learning was a wonderful, joyous experience. “As a student music teacher, I am privileged to realise early in my career that to teach music is to teach life. Seeing the children smiling and performing enthusiastically I realised that everyone deserves to be educated in, about, and through music.”

Community concert also to engage and educate 

The teaching culminated in a much-anticipated community concert which took place on Saturday 14 November 2020. The community concert is presented as an ‘informance’, a collaboration between informing and performance. 
“It enables us to engage with the audience by inviting them to sing and move. We also demonstrated to them the process, development and outcomes of the programme,” said Smith. 

“In only 12 lessons the Heidedal students were exposed to different music styles including classical music, jazz and African music, and learned to read and write music notation, and to play the recorder,” said Smith. 

News Archive

UFS study on cell development in top international science journal
2008-09-16

A study from the University of the Free State (UFS) on how the change in the packaging of DNA with cell development influenced the expression of genes, will be published in this week’s early edition of the prestigious international, peer-reviewed science journal, the Proceeding of the National Academy of Sciences of the USA (PNAS).

The PNAS journal has an impact factor of 10, which means that studies published in the journal are, on average, referred to by ten other scientific studies in a two year period. The South African Journal of Science, by comparison, has an impact factor of 0.7.

The UFS study, funded by the Wellcome Trust and the National Research Foundation (NRF), looked at how the change in the packaging of DNA with cell development influenced the expression of genes. It is very relevant to research on stem cells, an area of medicine that studies the possible use of undifferentiated cells to replace damaged tissue.

Prof. Hugh Patterton, of the Department of Microbial, Biochemical and Food Biotechnology at the UFS, who led the study, said: "We are extremely proud of this study. It was conceived in South Africa, it was performed in South Africa, the data were analysed in South Africa, and it was published from South Africa."

When a gene is expressed, the information encoded in the gene is used to manufacture a specific protein. In eukaryotes, which include humans, there is approximately 1m of DNA, containing the genes, in every cell. This length of DNA has to fit into a cell nucleus with a diameter of only about 10 micrometer. In order to fit the DNA into such a small volume, eukaryotic cells wrap their DNA onto successive protein balls, termed nucleosomes. Strings of nucleosomes, resembling a bead of pearls, is folded into a helix to form a chromatin fiber. The study from the UFS investigated how the binding of a specific protein, termed a linker histone, that binds to the length of DNA between nucleosomes, influenced the formation of the chromatin fiber and also the activity of genes.

"We found that the linker histone bound to chromatin in yeast, which we use as a model eukaryote, under conditions where virtually all the genes in the organism were inactive. It was widely believed that the binding of the linker histone caused the inactivation of genes. We studied the relationship between the amount of linker histone bound in the vicinity of each gene and the expression of that gene for all the genes in yeast, using genomic techniques. We made the surprising discovery that even through the linker histone preferentially bound to genes under conditions where the genes were shut off, this inactivation of genes was not caused by the binding of the linker histone and folding of the chromatin,” said Prof. Patterton.

He said: “Instead our data strongly suggested that the observed anti-correlation was due to the movement of enzymes along the DNA molecule, involved in processing the information in genes for the eventual manufacture of proteins. This movement of enzymes displaced the linker histones from the DNA. This finding now requires a rethink on aspects of how packaging of DNA influences gene activity."

Prof. Patterton said that his research group, using the Facility for Genomics and Proteomics as well as the Bioinformatics Node at the UFS, was currently busy with follow-up studies to understand how other proteins in nucleosomes affected the activities of genes, as well as with projects to understand how chemicals found in red wine and in green tea extended lifespan. "We are certainly having a marvelous time trying to understand the fundamental mechanisms of life, and the UFS is an exciting place to be if one was interested in studying life at the level of molecules," he said.


Media Release
Issued by: Lacea Loader
Assistant Director: Media Liaison
Tel: 051 401 2584
Cell: 083 645 2454
E-mail: loaderl.stg@ufs.ac.za  
18 September 2008
 

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