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25 February 2020 | Story Valentino Ndaba
Charné Ferreira
Kovsies is proud of Charné Ferreira one of just 12 candidates to be placed on the Honours Roll of the South African Institute of Chartered Accountants.

The South African Institute of Chartered Accountants (SAICA) recently announced the candidates who wrote and successfully met the requirements of the Assessment of Professional Competence (APC) examination. One of 2 024 names released was that of Charné Ferreira, a University of the Free State (UFS) alumna.

Ferreira was among 3 560 candidates who attempted the APC in November 2019. This gruelling part of her journey to becoming a Chartered Accountant (CA) was a culmination of many years of intensive education and training.

Now a Senior Associate at PricewaterhouseCoopers, Ferreira reflects on how her career started with the decision to take Accounting as a subject in high school. In her second- and third-year as a Kovsie student, Ferreira challenged herself to become a tutor. This gave her the opportunity to secure a position as an Academic Trainee at the UFS School of Accountancy.

Recognising outstanding performance
Not only did Ferreira pass the most demanding Chartered Accounting test in South Africa, but she excelled and earned a place on the institute’s prestigious APC Honours Roll. SAICA honours only 12 exceptional candidates for their aptitude and skill. 

Excellence to match market demands
According to Freeman Nomvalo, CEO of SAICA: “In many ways this is the toughest exam because it requires aspirant Chartered Accountants (CASA) to apply their technical academic knowledge from multiple disciplines to a single but complex real-life business case study. To pass, candidates must demonstrate high levels of the skills employers have told us they want in the next generation of CAs (SA).

“Succeeding at this final test of professional competence requires advanced levels of critical thinking, the ability to work with technology, and the capacity to assimilate new information under pressure over a five-day period which culminates in an eight-hour assessment. It’s gruelling but it’s exactly the kind of challenge successful candidates will soon face as qualified CAs (SA),” added Nomvalo.

A word to the wise
Looking back at the building blocks that led her to this point, Ferreira shared invaluable advice for future candidates. “Ask for help, speak up if you do not know, speak up if you are drowning in stress. Your career is not a sprint, it is okay if you fail, as long as you get up again and the most important thing is, make time to rest, do not be so hard on yourself,” she said.

In congratulating Ferreira and the other UFS alumni who passed the 2019 Assessment of Professional Competence, Prof Frans Prinsloo, Director: School of Accountancy, also paid tribute to the excellent work of the UFS academics in the School who play a vital role in developing the knowledge, skills and values of the next generation of accounting professionals. “These results attest to the quality of the Chartered Accountancy education offered by the UFS,” he said.

News Archive

UFS study on cell development in top international science journal
2008-09-16

A study from the University of the Free State (UFS) on how the change in the packaging of DNA with cell development influenced the expression of genes, will be published in this week’s early edition of the prestigious international, peer-reviewed science journal, the Proceeding of the National Academy of Sciences of the USA (PNAS).

The PNAS journal has an impact factor of 10, which means that studies published in the journal are, on average, referred to by ten other scientific studies in a two year period. The South African Journal of Science, by comparison, has an impact factor of 0.7.

The UFS study, funded by the Wellcome Trust and the National Research Foundation (NRF), looked at how the change in the packaging of DNA with cell development influenced the expression of genes. It is very relevant to research on stem cells, an area of medicine that studies the possible use of undifferentiated cells to replace damaged tissue.

Prof. Hugh Patterton, of the Department of Microbial, Biochemical and Food Biotechnology at the UFS, who led the study, said: "We are extremely proud of this study. It was conceived in South Africa, it was performed in South Africa, the data were analysed in South Africa, and it was published from South Africa."

When a gene is expressed, the information encoded in the gene is used to manufacture a specific protein. In eukaryotes, which include humans, there is approximately 1m of DNA, containing the genes, in every cell. This length of DNA has to fit into a cell nucleus with a diameter of only about 10 micrometer. In order to fit the DNA into such a small volume, eukaryotic cells wrap their DNA onto successive protein balls, termed nucleosomes. Strings of nucleosomes, resembling a bead of pearls, is folded into a helix to form a chromatin fiber. The study from the UFS investigated how the binding of a specific protein, termed a linker histone, that binds to the length of DNA between nucleosomes, influenced the formation of the chromatin fiber and also the activity of genes.

"We found that the linker histone bound to chromatin in yeast, which we use as a model eukaryote, under conditions where virtually all the genes in the organism were inactive. It was widely believed that the binding of the linker histone caused the inactivation of genes. We studied the relationship between the amount of linker histone bound in the vicinity of each gene and the expression of that gene for all the genes in yeast, using genomic techniques. We made the surprising discovery that even through the linker histone preferentially bound to genes under conditions where the genes were shut off, this inactivation of genes was not caused by the binding of the linker histone and folding of the chromatin,” said Prof. Patterton.

He said: “Instead our data strongly suggested that the observed anti-correlation was due to the movement of enzymes along the DNA molecule, involved in processing the information in genes for the eventual manufacture of proteins. This movement of enzymes displaced the linker histones from the DNA. This finding now requires a rethink on aspects of how packaging of DNA influences gene activity."

Prof. Patterton said that his research group, using the Facility for Genomics and Proteomics as well as the Bioinformatics Node at the UFS, was currently busy with follow-up studies to understand how other proteins in nucleosomes affected the activities of genes, as well as with projects to understand how chemicals found in red wine and in green tea extended lifespan. "We are certainly having a marvelous time trying to understand the fundamental mechanisms of life, and the UFS is an exciting place to be if one was interested in studying life at the level of molecules," he said.


Media Release
Issued by: Lacea Loader
Assistant Director: Media Liaison
Tel: 051 401 2584
Cell: 083 645 2454
E-mail: loaderl.stg@ufs.ac.za  
18 September 2008
 

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