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18 July 2020 | Story Amanda Thongha
Staff, students and other stakeholders of the University of the Free State (UFS) can look forward to a virtual music show honouring the values and beliefs of former President Nelson Mandela. Musicians such as Simple Stories, Sibongile Mngoma, Boitumelo Mohutsioa, and Lucy Sehloho have prepared performances that will be showcased on UFS communication platforms on 31 July. Concluding Mandela Month celebrations, the pre-recorded show will also feature performances by poets Braithan Moratwa and Zilungile Muqayi. The show is coordinated by the Division of Student Affairs at the UFS.  

Angelo Mockie, Senior Officer: Arts, Culture and Dialogue at Student Affairs, says the show was primarily produced to convey a message of hope, solidarity, and support to the UFS community. “We chose Mandela Month to publish it, because those are the values that he believed in. Now more than ever, we need to stand together as a community to find ways of adapting to the new normal.”

In a message to UFS staff acknowledging the life and legacy of Nelson Mandela, Prof Francis Petersen, Rector and Vice-Chancellor, said Madiba’s example of compassion and courage made him one of the best-known leaders in the world.
“His life was a true inspiration and his devotion to democracy, equality, learning, and caring for others have earned him the respect of communities around the world.

This year, the significance of Mandela Day will be even more important than ever before, as we demonstrate caring by looking after ourselves, our families, and those around us, while we navigate through the pandemic. Caring provides purpose, but also the motivation to fulfil that purpose. The COVID-19 pandemic should enable us to imagine a world that is fairer, safer, more stable, secure, and one that can prosper.”

Taking Action

Heeding the call to take action and inspire change on Nelson Mandela’s birthday, you can read the following articles about the UFS making every day a Mandela Day:

The shelter and the students – a triumph of social impact

South Campus delivers much-needed educational support during pandemic

News Archive

Nuclear Medicine on the forefront of cancer research
2017-07-10

Description: Nuclear Medicine on the forefront of cancer research Tags: Nuclear Medicine, cancer research, Dr Je’nine Horn-Lodewyk’s, tumour detection method, cancer, Department of Nuclear Medicine 

Dr Je’nine Horn-Lodewyk’s tumour detection method
could be the cost-effective breakthrough needed to decrease
the mortality rate in breast cancer patients.
Photo: Anja Aucamp

The field of Nuclear Medicine in South Africa and the rest of the world are expanding rapidly due to the development of hybrid cameras and new radiopharmaceuticals. These developments have a huge impact on the diagnosis and therapy of cancer.

The most advanced of these cameras, Positron emission tomography combined with normal CTs (PETCT), are not yet widely available in South Africa due to the cost of the cameras and the radiopharmaceuticals. A more cost-effective alternative can be of great benefit. To achieve this, the focus should be on developing new radiopharmaceuticals that can be used with the current cost-effective gamma cameras, according to University of the Free State researcher, Dr Je’nine Horn-Lodewyk from the Department of Nuclear Medicine.

Fluorodeoxyglucose (18F-FDG), a radiolabelled glucose analogue, is currently the radiopharmaceutical most commonly used in PET/CT imaging for mainly oncology indications. Although it is considered the gold standard for imaging in several malignancies, it does have certain disadvantages. An 18F-FDG PET/CT diagnostic imaging study can cost between R25 000 and R35 000 for a single patient in the private sector. The 18F-FDG is also more radioactive, which requires much stricter handling and shielding to avoid high radiation dosages to staff and patients.

Successful research potential innovative solution
In the search for the ideal radiopharmaceutical for tumour detection, the South African National Nuclear Energy Corporation (Necsa) developed a local synthesis process for ethylenedicysteine-deoxyglucose (EC-DG). EC-DG is also a glucose analogue similar to FDG. They succeeded in labelling the compound with Technetium-99-metastable-pertechnetate (99mTcO4-), the most common nuclear medicine isotope used for approximately 95% of nuclear medicine procedures, creating 99mTc-EC-DG.

In partnership with Dr Horn-Lodewyk, this compound was successfully used in various animal models and clinical scenarios, resulting in approval by the Medicine Control Council to use it in a human study. Research is also planned in order to investigate diagnostic accuracy in other cancers like lymphoma.  The end result of this research can produce a radiopharmaceutical that is cost effective, does not require the use of costly specialised equipment, has no significant side-effects, no special patient preparation, renders late imaging possible, and has decreased radiation risks.

Dr Horn-Lodewyk is grateful for the support of her mentor, Prof Anton Otto, as well as Dr Gert Engelbrecht, Head of the Department of Nuclear Medicine, Prof Jan Rijn Zeevaart from North-West University’s Preclinical Drug Development Platform and Necsa, and Judith Wagener from Necsa. This innovative research would also not have been possible without the financial assistance of Dr Glen Taylor and Eleanor van der Westhuizen in the Directorate of Research Development.

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