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31 July 2020
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As a public higher-education institution in South Africa with a responsibility to contribute to public discourse, the University of the Free State (UFS) will be presenting the 3rd UFS Thought-Leader Series in collaboration with Vrye Weekblad as part of the Vrystaat Literature Festival’s online initiative, VrySpraak-digitaal.
This year, higher-education institutions
globally are placed in the challenging context of COVID-19. Aware and grounded in the reality that the world will not return to the normality of pre-COVID-19, our responsibility as scholars still remains to contribute to public discourse and to offer
innovative solutions that will impact the lives of people nationally and globally in order to help them understand and adapt to a new world order.
Against this background and context, this year’s debates focus on ‘Post-COVID-19, Post-Crisis’,
with Health and Modelling, Politics, Economy, and Predictions for 2021 as the sub-themes. Placed in a COVID-19 context, and in lieu of the Vrystaat Arts Festival,
the series will be presented virtually in the form of one webinar per month during the period August 2020 to November 2020.
Date: 13 August 2020
Topic: Health
and Modelling
Time: 11:30-13:00
RSVP: Alicia Pienaar, pienaaran1@ufs.ac.za
Facilitator:
Max du Preez
Editor: Vrye Weekblad
Biography
Introduction and welcome:
Prof Francis Petersen
Rector and Vice-Chancellor, UFS
Panellists:
Prof Salim Abdool Karim
Director: Centre for the AIDS Programme of Research in South Africa (CAPRISA)
Chair: South African Ministerial Advisory Committee on COVID-19
Biography
Prof Glenda Gray
President and CEO: South African Medical Research Council (SAMRC)
Biography
Prof Felicity Burt
NRF-DST South African Research Chair in vector-borne and zoonotic pathogens research
Biography
New research informs improved treatment of brain inflammation
2017-10-13
Dr Adepemi Ogundeji, researcher in the Department of Microbial,
Biochemical and Food Biotechnology at the
University of the Free State,and Dr Olihile Sebolai,
her study leader from the same department.
Photo: Charl Devenish
Microbiologist Dr Adepemi Ogundeji has uncovered a new use for an old medicine that can potentially save lives and money. Under the guidance of her study leader, Dr Olihile Sebolai, Dr Ogundeji set out to fight a fungal disease caused by Cryptococcus neoformans. Drs Ogundeji and Sebolai are from the University of the Free State Department of Microbial, Biochemical and Food Biotechnology.
Dr Ogundeji is passionate about education. “My aim will always be to transfer knowledge and skills in the microbiology field,” she said. “Dr Ogundeji’s study is celebrated in that it found a new purpose for existing medicines. An advantage of repositioning old medicines is by-passing clinical trials, which sometimes take 20 years, and the safety of such medicines is already known,” Dr Sebolai, explained.
Cryptococcus infections are difficult to control and often lead to brain inflammation. In layman’s terms: “Your brain is on fire”. People with HIV/Aids are especially vulnerable, surviving only about three months without treatment. Such patients may present with a Cryptococcus-emergent psychosis, and some with an out-of-control inflammatory condition when initiated on ARVs.
Dr Ogundeji found that the clinically recommended dosage of aspirin (anti-inflammatory medicine), and quetiapine (anti-psychotic medicine) is sufficient to control the infection. Her exceptional work was readily published in some of the foremost journals in her field, namely, Antimicrobial Agents and Chemotherapy and Frontiers in Microbiology