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Forensics expert elected for second term to solve SA’s crimes

10 June 2020 | Story Leonie Bolleurs | Photo Supplied

Karen_read more — Dr Ehlers was appointed to serve on the National Forensic Oversight and Ethics Board of 10 members for a second term, based on her knowledge in the field of forensic sciences.

Dr Karen Ehlers from the Department of Genetics at the University of the Free State (UFS) was elected as a member of the National Forensic Oversight and Ethics Board (NFOEB) for a second term.

Dr Ehlers has been appointed to the board of 10 members based on her knowledge in the field of forensic sciences. She is currently conducting research focusing on the forensic application of Y-STR markers, the statistical analysis of DNA profiles, and touch DNA.

Making valuable contributions

Her expertise in the field of forensic genetics assists the board – which also handles complaints about alleged violations relating to the abuse of DNA samples and forensic DNA profiles – to oversee the operations of the Forensic Science Laboratory and the National Forensic DNA Database (NFDD).

“The knowledge I gained from my current research at the UFS has enabled me to make valuable contributions to the board and its recommendations to the Minister of Police,” says Dr Ehlers.

In her first term as member of the Board – following regular tracking and analysis of reports, the Board noted an increase in the number of outstanding forensic investigative leads – (hits on the National Forensic DNA Database) that were not followed up.

“After we made enquiries, it was determined that the provincial task teams that were to follow up on the leads, were ad hoc structures that lacked the necessary resources. The Board addressed this shortfall by engaging with various stakeholders and helping to establish permanent structures, called Forensic Investigative Units, with dedicated resources – both human and material – to effectively follow up on all forensic DNA investigative leads. The finalised Regulations were published for comment in the Government Gazette on 27 March 2020,” says Dr Ehlers.

Lowering SA crime rate

While serving on this board, she is ensuring that South Africa has a functioning DNA database that contributes to lowering the crime rate in the country. “As a member of the board, I hope to add value to its functioning. I feel that in the future, science will play an even bigger role in crime prevention, detection, and the solving of crimes,” she states.

Dr Ehlers is Programme Director of the Forensic Sciences Programme in the Department of Genetics. She teaches the Crime Scene Management module to second-year students and supervises seven honours, five MSc, and three PhD students.

Besides her appointment as member of the NFOEB, she values the work she is doing with her students. “The highlight of my career was when my first group of BScHons students in Forensic Genetics graduated and were shortly thereafter appointed by the Forensic Sciences Laboratory as DNA analysts,” she says.

News Archive

Nanotechnology breakthrough at UFS

2010-08-19

Ph.D students, Chantel Swart and Ntsoaki Leeuw

Scientists at the University of the Free State (UFS) made an important breakthrough in the use of nanotechnology in medical and biological research. The UFS team’s research has been accepted for publication by the internationally accredited Canadian Journal of Microbiology.

The UFS study dissected yeast cells exposed to over-used cooking oil by peeling microscopically thin layers off the yeast cells through the use of nanotechnology.

The yeast cells were enlarged thousands of times to study what was going on inside the cells, whilst at the same time establishing the chemical elements the cells are composed of. This was done by making microscopically small surgical incisions into the cell walls.

This groundbreaking research opens up a host of new uses for nanotechnology, as it was the first study ever in which biological cells were surgically manipulated and at the same time elemental analysis performed through nanotechnology. According to Prof. Lodewyk Kock, head of the Division Lipid Biotechnology at the UFS, the study has far reaching implications for biological and medical research.

The research was the result of collaboration between the Department of Microbial, Biochemical and Food Biotechnology, the Department of Physics (under the leadership of Prof. Hendrik Swart) and the Centre for Microscopy (under the leadership of Prof.Pieter van Wyk).

Two Ph.D. students, Chantel Swart and Ntsoaki Leeuw, overseen by professors Kock and Van Wyk, managed to successfully prepare yeast that was exposed to over-used cooking oil (used for deep frying of food) for this first ever method of nanotechnological research.

According to Prof. Kock, a single yeast cell is approximately 5 micrometres long. “A micrometre is one millionth of a metre – in laymen’s terms, even less than the diameter of a single hair – and completely invisible to the human eye.”

Through the use of nanotechnology, the chemical composition of the surface of the yeast cells could be established by making a surgical incision into the surface. The cells could be peeled off in layers of approximately three (3) nanometres at a time to establish the effect of the oil on the yeast cell’s composition. A nanometre is one thousandth of a micrometre.

Each cell was enlarged by between 40 000 and 50 000 times. This was done by using the Department of Physics’ PHI700 Scanning Auger Nanoprobe linked to a Scanning Electron Microscope and Argon-etching. Under the guidance of Prof. Swart, Mss. Swart en Leeuw could dissect the surfaces of yeast cells exposed to over-used cooking oil.

The study noted wart like outgrowths - some only a few nanometres in diameter – on the cell surfaces. Research concluded that these outgrowths were caused by the oil. The exposure to the oil also drastically hampered the growth of the yeast cells. (See figure 1)

Researchers worldwide have warned about the over-usage of cooking oil for deep frying of food, as it can be linked to the cause of diseases like cancer. The over-usage of cooking oil in the preparation of food is therefore strictly regulated by laws worldwide.

The UFS-research doesn’t only show that over-used cooking oil is harmful to micro-organisms like yeast, but also suggests how nanotechnology can be used in biological and medical research on, amongst others, cancer cells.

Figure 1. Yeast cells exposed to over-used cooking oil. Wart like protuberances/ outgrowths (WP) is clearly visible on the surfaces of the elongated yeast cells. With the use of nanotechnology, it is possible to peel off the warts – some with a diameter of only a few nanometres – in layers only a few nanometres thick. At the same time, the 3D-structure of the warts as well as its chemical composition can be established.

Media Release
Issued by: Mangaliso Radebe
Assistant Director: Media Liaison
Tel: 051 401 2828
Cell: 078 460 3320
E-mail: radebemt@ufs.ac.za
18 August 2010

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