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10 June 2020 | Story Leonie Bolleurs | Photo Supplied
Dr Ehlers was appointed to serve on the National Forensic Oversight and Ethics Board of 10 members for a second term, based on her knowledge in the field of forensic sciences.

Dr Karen Ehlers from the Department of Genetics at the University of the Free State (UFS) was elected as a member of the National Forensic Oversight and Ethics Board (NFOEB) for a second term.

Dr Ehlers has been appointed to the board of 10 members based on her knowledge in the field of forensic sciences. She is currently conducting research focusing on the forensic application of Y-STR markers, the statistical analysis of DNA profiles, and touch DNA.

Making valuable contributions
Her expertise in the field of forensic genetics assists the board – which also handles complaints about alleged violations relating to the abuse of DNA samples and forensic DNA profiles – to oversee the operations of the Forensic Science Laboratory and the National Forensic DNA Database (NFDD). 

“The knowledge I gained from my current research at the UFS has enabled me to make valuable contributions to the board and its recommendations to the Minister of Police,” says Dr Ehlers. 

In her first term as member of the Board – following regular tracking and analysis of reports, the Board noted an increase in the number of outstanding forensic investigative leads – (hits on the National Forensic DNA Database) that were not followed up.

“After we made enquiries, it was determined that the provincial task teams that were to follow up on the leads, were ad hoc structures that lacked the necessary resources. The Board addressed this shortfall by engaging with various stakeholders and helping to establish permanent structures, called Forensic Investigative Units, with dedicated resources – both human and material – to effectively follow up on all forensic DNA investigative leads. The finalised Regulations were published for comment in the Government Gazette on 27 March 2020,” says Dr Ehlers.

Lowering SA crime rate
While serving on this board, she is ensuring that South Africa has a functioning DNA database that contributes to lowering the crime rate in the country. “As a member of the board, I hope to add value to its functioning. I feel that in the future, science will play an even bigger role in crime prevention, detection, and the solving of crimes,” she states.

Dr Ehlers is Programme Director of the Forensic Sciences Programme in the Department of Genetics. She teaches the Crime Scene Management module to second-year students and supervises seven honours, five MSc, and three PhD students. 

Besides her appointment as member of the NFOEB, she values the work she is doing with her students. “The highlight of my career was when my first group of BScHons students in Forensic Genetics graduated and were shortly thereafter appointed by the Forensic Sciences Laboratory as DNA analysts,” she says. 

News Archive

Researchers focus on parrots, poultry and phage therapy
2014-10-10

Photo: en.wikipedia

Veterinary biotechnology focuses on microbial and molecular biological approaches to veterinary illnesses. The group working on veterinary biotechnology research at the University of the Free State (UFS) consists of two academic staff members, Prof Rob Bragg and Dr Charlotte Boucher, two post-doctoral fellows, Drs Chris Theron and Arina Hitzeroth, five PhD and three honours students.

The group has three research focus areas.

Dr Boucher says, “Our main focus area is infectious coryza in poultry, caused by the bacterium Avibacterium paragalliarum. The aim is the control of the disease, mainly through improvement of vaccines, understanding the immune response and improved biosecurity. A key objective is improving methods for serotyping; studying of selected surface antigens and investigating the influence recently discovered bacteriophages might have on virulence. We have co-operative projects with research groups in China, India and Israel.

“The second focus area is an expression system co-developed with the National Institute for Agronomic Research (INRA), France. The flagship project is the expression of the coat protein gene of the beak and feather disease virus, a disease affecting parrots, currently threatening the endangered Cape parrot. This system has led to the development of serological tests, currently under patenting. The application of this system has been extended to human-related diseases, with two interdisciplinary projects underway, co-working with Profs Muriel Meiring and Felicity Burt. Prof Meiring is working on diseases causing bleeding disorders, such as blood-clotting impairment, while Prof Burt is working on viral infections causing haemorrhagic (bleeding) disorders.

“We are also researching disease control in a post-antibiotic era, investigating the potential of phage-therapy by targeting and destroying pathogenic islands within a host, with reduced side-effects on the host itself.

“We have smaller projects, including an interdisciplinary project with Zoology, looking at the protein profile of amphibian (frog) secretions with the focus on antimicrobial activity, as these secretions assist with protecting amphibian skin against infections.”  


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