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18 June 2020 | Story Nitha Ramnath | Photo Supplied
Mischke Bouwer.

Mischke Bouwer was recently awarded a Fulbright scholarship to study her PhD in Geoscience at the Southern Illinois University (SIU). The duration of the programme at SIU is five years, starting in August 2020.

Fulbright is a scholarship programme that recruits students from all over the world in any field of study to do their postgraduate studies in America. This is done through funding from Fulbright, together with the country's government and American universities. 

“This is not only a funding scholarship, but a supportive community! It really does feel like teamwork so far. The people from Fulbright ensure that the students feel as comfortable and enlightened as possible when leaving the country, and I am sure it will be the same when I arrive in America,” says Mischke.

Mischke considers herself an average girl who grew up in Pretoria; she enrolled at the UFS for a BSc in Geology from 2014 to 2016, followed by an Honours in Geology in 2017, and MSc in Soil Science. 
“I took a big chance by applying for a Fulbright scholarship but did not expect anything, as I felt I would never be good enough – but look where I am now,” says Mischke.

“I am speechless about the scholarship I received. There are many people I would like to thank who helped me along the way to achieve this scholarship. I would love this opportunity to thank all my lecturers from the UFS, both in the departments of Geology and Soil Science. Thanks to my supervisors for always believing in me. A special thanks to Prof Cornie van Huyssteen who was fully behind me, impacting my way of thinking, and teaching me a lot in two years.”

Mischke dedicates this scholarship to the late Prof Marian Tredoux, a true scientist and lecturer in the Department of Geology, who not only contributed greatly to the sciences, but truly impacted her students. “She inspired me to work hard and showed me an example of what a woman in science could be,” says Mischke.

She encourages students to apply for this scholarship, adding that there is nothing to lose. According to Mischke, students are much smarter than they would like to believe and should therefore always be mindful that their future is way brighter than they think.

“Make your role model YOU in 10 years and keep it that way! This way you always have someone to strive for!” says Mischke.

Mischke works on the absorption potential of arsenic and selenium in the field of environmental geochemistry and geochemical modelling. She hopes to return to South Africa with this knowledge and to make a difference in the remediation and rehabilitation of mines. 

News Archive

Nuclear Medicine on the forefront of cancer research
2017-07-10

Description: Nuclear Medicine on the forefront of cancer research Tags: Nuclear Medicine, cancer research, Dr Je’nine Horn-Lodewyk’s, tumour detection method, cancer, Department of Nuclear Medicine 

Dr Je’nine Horn-Lodewyk’s tumour detection method
could be the cost-effective breakthrough needed to decrease
the mortality rate in breast cancer patients.
Photo: Anja Aucamp

The field of Nuclear Medicine in South Africa and the rest of the world are expanding rapidly due to the development of hybrid cameras and new radiopharmaceuticals. These developments have a huge impact on the diagnosis and therapy of cancer.

The most advanced of these cameras, Positron emission tomography combined with normal CTs (PETCT), are not yet widely available in South Africa due to the cost of the cameras and the radiopharmaceuticals. A more cost-effective alternative can be of great benefit. To achieve this, the focus should be on developing new radiopharmaceuticals that can be used with the current cost-effective gamma cameras, according to University of the Free State researcher, Dr Je’nine Horn-Lodewyk from the Department of Nuclear Medicine.

Fluorodeoxyglucose (18F-FDG), a radiolabelled glucose analogue, is currently the radiopharmaceutical most commonly used in PET/CT imaging for mainly oncology indications. Although it is considered the gold standard for imaging in several malignancies, it does have certain disadvantages. An 18F-FDG PET/CT diagnostic imaging study can cost between R25 000 and R35 000 for a single patient in the private sector. The 18F-FDG is also more radioactive, which requires much stricter handling and shielding to avoid high radiation dosages to staff and patients.

Successful research potential innovative solution
In the search for the ideal radiopharmaceutical for tumour detection, the South African National Nuclear Energy Corporation (Necsa) developed a local synthesis process for ethylenedicysteine-deoxyglucose (EC-DG). EC-DG is also a glucose analogue similar to FDG. They succeeded in labelling the compound with Technetium-99-metastable-pertechnetate (99mTcO4-), the most common nuclear medicine isotope used for approximately 95% of nuclear medicine procedures, creating 99mTc-EC-DG.

In partnership with Dr Horn-Lodewyk, this compound was successfully used in various animal models and clinical scenarios, resulting in approval by the Medicine Control Council to use it in a human study. Research is also planned in order to investigate diagnostic accuracy in other cancers like lymphoma.  The end result of this research can produce a radiopharmaceutical that is cost effective, does not require the use of costly specialised equipment, has no significant side-effects, no special patient preparation, renders late imaging possible, and has decreased radiation risks.

Dr Horn-Lodewyk is grateful for the support of her mentor, Prof Anton Otto, as well as Dr Gert Engelbrecht, Head of the Department of Nuclear Medicine, Prof Jan Rijn Zeevaart from North-West University’s Preclinical Drug Development Platform and Necsa, and Judith Wagener from Necsa. This innovative research would also not have been possible without the financial assistance of Dr Glen Taylor and Eleanor van der Westhuizen in the Directorate of Research Development.

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