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19 May 2020 | Story Cornelius Hagenmeier and Prof Colin Chasi | Photo Supplied
Cornelius Hagenmeier.

Africa is defined by colonial borders, within which states attempt to build viable systems. Universities are a significant part of the national innovation systems that seek to change the socio-economic and other fortunes of the many poor and marginalised Africans. As Africa approaches the celebrations on the occasion of the 57th anniversary of the founding of the Organisation of African Unity (OAU), the COVID-19 crisis reveals – if we are willing to see it – that there is a need to focus much attention on intra-Africa internationalisation programmes for African higher education.

Because national socio-economic and health systems are often inadequate, Covid-19 protects unprecedented human and social suffering for many on the continent. To try and stave off this harm throughout the continent, borders have been closed and economies have been stifled. Except for the ‘repatriation’ of citizens, international travel has become all but impossible. Africans have, as never before, been bound to colonial boundaries, which are preserved according to a principle called uti-possidetis. This principle was reluctantly ratified by members of the Organisation of African Union (OAU) in July 1964. This ratification was reluctant, because leaders recognised that African boundaries were arbitrarily and chaotically imposed in the scramble for Africa. These borders were not developed by internal historical processes. In consequence, they divide kith from kin, limiting trade and commerce across the continent. Nevertheless, leaders adopted the uti-possidetis principle for fear that allowing the contestation of these borders would likely yield territorial wars that would bring heightened misery without end. 

State power in Africa today is exercised within postcolonial borders that continue to be weak and porous. It is also exercised by states that are themselves generally weak. These states take their health-promoting actions to neighbourhoods that often have inadequate socio-economic and health systems for combating COVID-19. They entrap us in compartments that produce lives that are short and brutish.  We would do well to ask how we can decolonise our borders in ways that set us free to change socio-economic fortunes.

Within the confining arrangements of state power, the health threat of the COVID-19 pandemic has been met with almost every African country adopting stringent health precautions, often resulting in sudden, sharp economic declines. With this, the livelihoods of millions are in jeopardy. African higher education has not escaped the resultant challenges.
The higher education sector is struggling to adapt. To be sure, in many ways, it is producing mighty work. Many books and journals will write about how systems moved significant aspects of teaching and learning online, often with great success, sometimes with great frustrations. At the same time, Africans rightly expect higher education systems to contribute to finding immediate responses to the pandemic threat. In many cases, universities are assisting by researching the coronavirus genome, developing effective and cost-efficient necessities such as personal protective equipment and ventilators; or by researching effective vaccines, medication, and public-health interventions. However, it is difficult to find excellent examples of how these steps are changing national narratives, particularly those that bind us to colonial miseries.

The African Union (AU), which is the successor to the OAU, is trying to build multilateral efforts. It has developed an ‘Africa Joint Continental Strategy for COVID-19 Outbreak’ and established an ‘Africa Taskforce for Coronavirus’. These efforts seek to foster collaboration between multilateral stakeholders. For the African Union recognises that to adequately address the crises occasioned by COVID-19, it is necessary that member states, African Union agencies, the World Health Organization and other partners work synergistically to avoid duplication and to maximise efficiencies, given that resources are extremely constrained. 

A central tenet of the OAU is African solidarity. Member states have undertaken to coordinate and intensify their cooperation and efforts to achieve a better life for the people of Africa. It is encouraging that the AU’s Chairperson, President Cyril Ramaphosa, refers to pan-Africanist ideas when he calls for the ‘strengthening of the bonds of solidarity that exist between us as Africans’ (24 April 2020). Ideas of African togetherness, underpinned by the philosophy of ubuntu, must inspire African solidarity. They are more relevant than ever before. 

It is vital that we think, beyond this COVID-19 crisis, of how long-run coordination of African higher education institutions in Africa must produce continent-wide systems of innovation that take us out of perpetual poverty, disease, and unnecessary deaths.

African higher education is struggling to define its place in the rapidly changing realities of the continent. Many institutions are driven to merely concentrate on how they will survive, or on how sprouting areas of excellence will make it through adverse financial conditions that emerge. 

Africa is at a critical juncture. How we make it through COVID-19 and what we learn from doing so, will determine whether Africa unites as we shape the post-COVID-19 future.

Prof Colin Chasi. (Photo: Anja Aucamp.) 

Periods of great strife, devastation, and hardship are opportunities for radical renewal and quantum leaps in development. But we must have the courage to take those opportunities. If we have the courage to unleash our universities in the kinds of continent-changing work that is needed, the fortunes of African countries are, after all,  tied together (no matter what colonial boundaries and divisions may say). 

The decisions that will be made during and in the wake of the pandemic will determine whether the crisis and its aftermath will allow the continent to focus on becoming a prospering, united world power, or whether national egoism (tied to colonial histories) will prevail and hinder sustainable development. 

How African higher education evolves in the post-pandemic world will largely depend on whether universities will be able to embrace the interconnectedness and interdependency of Africa’s social and economic realities. African higher education systems must escape the temptation to respond to immediate challenges in isolation. These times should teach us that when your neighbour catches the flu, your home economy suffers too. However, where people should observe social distancing to overcome the flu, economies must reach across borders if they are to flourish in markets large enough to truly impart value to ideas, services, and goods.

Higher education should serve African people by advancing social transformation and development through collaboration in skills development and research. Through intra-African partnerships and collaborations, African universities can make significant contributions to finding responses to the peculiar public health and medical challenges of emerging African societies and shaping a prosperous and unified post-pandemic Africa.

Many African higher education institutions excel in specific fields. The quality of programmes and research is not uniform throughout institutions. We need to lead the world in recognising each other’s strengths to produce intensified collaboration in capacity development and research. In doing this work, higher education will go far beyond repeating and mimicking colonial patterns, or if you wish, it will go beyond colonial boundaries. It will be a key driver in finding responses to the cross-cutting challenges that need to be resolved to fulfil the aspirations of Africa’s Agenda 2063. Indeed, by leveraging the complementary strengths of its higher education institutions, the continental higher education system could become a critical force shaping a positive post-COVID-19 African reality. Pan-Africanism in higher education should not be limited to isolated initiatives such as the development of the Pan-African University, but should establish a framework for sustained continental academic collaboration.  

As African universities prepare to contribute to the celebrations for the 57th anniversary of the OAU, they should consider how they can strengthen intra-African collaboration to achieve the pan-African vision of ‘an integrated, prosperous and peaceful Africa, driven by its own citizens, representing a dynamic force in the international arena’ (AU vision statement). 

Fortunately, there are excellent points of departure. Laudable programmes such as the Association of African Universities staff exchange programme already exist, yet much of the intra-African higher education collaboration is still financed by foreign donors. The African Union, African governments, and the African higher education sector influence the structure of those programmes through consultation, and consequently minimise the risk of them responding to the international perceptions of African needs rather than real African needs. This should be strengthened, not least through committing equity to the formulation of joint programmes. 

For the brave new world in which we must make space for our children to thrive, brave new African frameworks for collaboration should be developed. Energy must be invested in removing obstacles to African higher education collaboration. Some of the things that need to be done are well known. Practical measures could include strengthening the harmonisation of African higher education accreditation and quality assurance mechanisms, establishing an African credit recognition and transfer system, and fast-tracking the harmonisation of African higher education programmes. The celebration of 2020 Africa Day should encourage African higher education to work towards devising a strategy for strengthening collaboration, which would assist the continent in shaping a positive post-COVID-19 African reality. If this can be achieved, African universities could emerge as genuine agents of achieving solidarity and development in post-pandemic Africa, and thus realising the ideals of the OAU.

News Archive

Research contributes to improving quality of life for cancer patients
2016-11-21

Description: Inorganic Chemistry supervisors  Tags: Inorganic Chemistry supervisors

Inorganic Chemistry supervisors in the Radiopharmacy
Laboratory during the preparation of a typical complex
mixture to see how fast it reacts. Here are, from the left,
front: Dr Marietjie Schutte-Smith, Dr Alice Brink
(both scholars from the UFS Prestige
Scholar Programme), and Dr Truidie Venter (all three
are Thuthuka-funded researchers).
Back: Prof André Roodt and Dr Johan Venter.
Photo: Supplied

Imagine that you have been diagnosed with bone cancer and only have six months to live. You are in a wheelchair because the pain in your legs is so immense that you can’t walk anymore – similar to a mechanism eating your bones from the inside.

You are lucky though, since you could be injected with a drug to control the pain so effective that you will be able to get out of the wheelchair within a day-and-a-half and be able to walk again. Real-life incidents like these provide intense job satisfaction to Prof André Roodt, Head of Inorganic Chemistry at the University of the Free State (UFS). The research, which is conducted by the Inorganic Group at the UFS, contributes greatly to the availability of pain therapy that does not involve drugs, but improves the quality of life for cancer patients.

The research conducted by the Inorganic Group under the leadership of Prof Roodt, plays a major role in the clever design of model medicines to better detect and treat cancer.

The Department of Chemistry is one of approximately 10 institutions worldwide that conducts research on chemical mechanisms to identify and control cancer. “The fact that we are able to cooperate with the Departments of Nuclear Medicine and Medical Physics at the UFS, the Animal Research Centre, and other collaborators in South Africa and abroad, but especially the methodology we utilise to conduct research (studying the chemical manner in which drugs are absorbed in cancer as well as the time involved), enhances the possibility of making a contribution to cancer research,” says Prof Roodt.

Technique to detect cancer spots on bone
According to the professor, there are various ways of detecting cancer in the body. Cancer can, inter alia, be identified by analysing blood, X-rays (external) or through an internal technique where the patient is injected with a radioactive isotope.

Prof Roodt explains: “The doctor suspects that the patient has bone cancer and injects the person with a drug consisting of an isotope (only emits X-rays and does no damage to tissue) that is connected to a phosphonate (similar to those used for osteoporosis). Once the drug is injected, the isotope (Technetium-99m) moves to the spot on the bone where the cancer is located. The gamma rays in the isotope illuminate the area and the doctor can see exactly where treatment should be applied. The Technetium-99m has the same intensity gamma rays as normal X-rays and therefore operates the same as an internal X-ray supply.” With this technique, the doctor can see where the cancer spots are within a few hours.

The same technique can be used to identify inactive parts of the brain in Alzheimer patients, as well as areas of the heart where there is no blood supply or where the heart muscle is dead.

Therapeutic irradiation of cancer
For the treatment of pain connected with cancer, the isotope Rhenium-186 is injected. Similar to the manner in which the Technetium-99m phosphonate compound is ingested into the body, the Rhenium-186 phosphonate travels to the cancer spots. Patients thus receive therapeutic irradiation – a technique known as palliative therapy, which is excellent for treating pain. A dosage of this therapy usually lasts for about two months.

The therapy is, however, patient specific. The dosages should correspond with the occurrence and size of cancer spots in the patient’s body. First, the location of the cancer will be determined by means of a technetium scan. After that, the size of the area where the cancer occurs has to be determined. The dosage for addressing total pain distribution will be calculated according to these results.

Technique to detect cancer spots on soft tissue
Another technique to detect cancer as spots on bone or in soft tissue and organs throughout the body is by utilising a different type of irradiation, a so-called PET isotope. The Fluor-18 isotope is currently used widely, and in Pretoria a machine called a cyclotron was produced by Dr Gerdus Kemp, who is a former PhD graduate from the Inorganic Research Group. The F-18 is then hidden within a glucose molecule and a patient will be injected with the drug after being tranquillised and after the metabolism has been lowered considerably. The glucose, which is the ‘food' that cancer needs to grow, will then travel directly to the cancer area and the specific area where the cancer is located will thus be traced and ‘illuminated’ by the Fluor-18, which emits its own 'X-rays'.

In the late 80s, Prof Roodt did his own postdoctoral study on this research in the US. He started collaborating with the Department of Nuclear Medicine at the UFS in the early 90s, when he initiated testing for this research.

Through their research of more than 15 years, the Inorganic Group in the Department of Chemistry has made a major contribution to cancer research. Research on mechanisms for the detection of cancer, by designing new clever chemical agents, and the chemical ways in which these agents are taken up in the body, especially contributes to the development in terms of cancer therapy and imaging, and has been used by a number of hospitals in South Africa.

The future holds great promise
Prof Roodt and his team are already working on a bilateral study between the UFS and Kenya. It involves the linking of radio isotopes, as mentioned above, to known natural products (such as rooibos tea), which possess anti-cancer qualities.

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