Latest News Archive

Please select Category, Year, and then Month to display items
Previous Archive
25 May 2020 | Story Prof Danie Brand | Photo iStock

We are indeed privileged to have this paper from Prof Toyin Falola to include in our celebrations of Africa Day. Toyin Falola is a world-renowned African. A scholar of African history and African studies, he holds the Jacob and Frances Sanger Mossiker Chair in the Humanities at the University of Texas, Austin. He has published, as author or editor, more than 100 scholarly books on topics ranging from diaspora, migration, empire and globalization to intellectual history, international relations, religion and culture. He has been awarded seven honorary doctorates and has received, among many other awards, the Distinguished Africanist Award from the African Studies Association, the Ibadan Foundation Award for Professional Excellence in Scholarship and the Cheikh Anta Diop Award for Excellence in African Studies. He served as Vice President of UNESCO’s International Scientific Committee, Slave Route Project from 2011 – 2015 and currently is a member of the Carnegie African Diaspora Fellows Programme and the International Committee of the Thabo Mbeki African Leadership Institute at UNISA.

In this wide-ranging paper, originally presented as keynote address at the Visions of African Unity (1930s – 2018) conference at the University of the Free State, Prof Falola begins with a tour of the intellectual history of ideas of African Continentalism (Pan-Africanism / African Unity), from Henry Sylvester Williams, through WEB du Bois, Marcus Garvey, George Padmore and Julius Nyerere, to Kwame Nkrumah. He then describes the current institutional landscape of African unity and present-day intellectual versions of African Continentalism. Asking, and answering the question ‘Why must Africa unite?’, he then proceeds, on the basis of a consideration of more contemporary intellectual versions of African continentalism such as Black Consciousness, Black Nationalism, Afropolitanism, and now Afrofuturism (which he depicts as ‘ideological dispensations of true African cultural recovery and re-orientation’), to propose a disaggregated approach to contemporary African unity that is not fixated on global-Northern models. This means that unity should (re)start small, working territorially from regional units toward a continental unit, on the one hand; and on the other, seeking unity and cooperation around discrete substantive themes, from the more obvious and traditional, such as economic policy, global politics and a reformed unified political and military system, to the less, such as common educational policy, synergizing science and technology with African culture(s) and language, culture and literary exchange.

We thank him for the gift.

News Archive

Nuclear Medicine on the forefront of cancer research
2017-07-10

Description: Nuclear Medicine on the forefront of cancer research Tags: Nuclear Medicine, cancer research, Dr Je’nine Horn-Lodewyk’s, tumour detection method, cancer, Department of Nuclear Medicine 

Dr Je’nine Horn-Lodewyk’s tumour detection method
could be the cost-effective breakthrough needed to decrease
the mortality rate in breast cancer patients.
Photo: Anja Aucamp

The field of Nuclear Medicine in South Africa and the rest of the world are expanding rapidly due to the development of hybrid cameras and new radiopharmaceuticals. These developments have a huge impact on the diagnosis and therapy of cancer.

The most advanced of these cameras, Positron emission tomography combined with normal CTs (PETCT), are not yet widely available in South Africa due to the cost of the cameras and the radiopharmaceuticals. A more cost-effective alternative can be of great benefit. To achieve this, the focus should be on developing new radiopharmaceuticals that can be used with the current cost-effective gamma cameras, according to University of the Free State researcher, Dr Je’nine Horn-Lodewyk from the Department of Nuclear Medicine.

Fluorodeoxyglucose (18F-FDG), a radiolabelled glucose analogue, is currently the radiopharmaceutical most commonly used in PET/CT imaging for mainly oncology indications. Although it is considered the gold standard for imaging in several malignancies, it does have certain disadvantages. An 18F-FDG PET/CT diagnostic imaging study can cost between R25 000 and R35 000 for a single patient in the private sector. The 18F-FDG is also more radioactive, which requires much stricter handling and shielding to avoid high radiation dosages to staff and patients.

Successful research potential innovative solution
In the search for the ideal radiopharmaceutical for tumour detection, the South African National Nuclear Energy Corporation (Necsa) developed a local synthesis process for ethylenedicysteine-deoxyglucose (EC-DG). EC-DG is also a glucose analogue similar to FDG. They succeeded in labelling the compound with Technetium-99-metastable-pertechnetate (99mTcO4-), the most common nuclear medicine isotope used for approximately 95% of nuclear medicine procedures, creating 99mTc-EC-DG.

In partnership with Dr Horn-Lodewyk, this compound was successfully used in various animal models and clinical scenarios, resulting in approval by the Medicine Control Council to use it in a human study. Research is also planned in order to investigate diagnostic accuracy in other cancers like lymphoma.  The end result of this research can produce a radiopharmaceutical that is cost effective, does not require the use of costly specialised equipment, has no significant side-effects, no special patient preparation, renders late imaging possible, and has decreased radiation risks.

Dr Horn-Lodewyk is grateful for the support of her mentor, Prof Anton Otto, as well as Dr Gert Engelbrecht, Head of the Department of Nuclear Medicine, Prof Jan Rijn Zeevaart from North-West University’s Preclinical Drug Development Platform and Necsa, and Judith Wagener from Necsa. This innovative research would also not have been possible without the financial assistance of Dr Glen Taylor and Eleanor van der Westhuizen in the Directorate of Research Development.

We use cookies to make interactions with our websites and services easy and meaningful. To better understand how they are used, read more about the UFS cookie policy. By continuing to use this site you are giving us your consent to do this.

Accept