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09 May 2020

Dear Students

UPDATE ON DEVELOPMENTS AT THE UFS

I hope you are well, healthy, and safe. I also hope that you are engaging with your friends and lecturers regularly, and that you have settled into the online learning environment. As with communities around the world – including higher education institutions – Kovsies also feel the impact of the exceptional circumstances resulting from the global COVID-19 outbreak. So much has changed, and our lives are directly and indirectly affected. It is a true test of our resilience and ability to adapt to a changing environment.

I know that it has not always been easy for you – none of us were prepared for a global pandemic of this magnitude. But I also see this as an opportunity for us to develop our learning and teaching model and to find ways of further enhancing the university’s processes and systems.

The suspension of the academic programme and the national lockdown had a huge effect on our staff and students. We had to act fast to ensure the continuation of the 2020 academic programme. Our first priority was to develop low-tech online and distance approaches to learning and teaching. Consequently, we developed support for academic staff and students to navigate the new online learning environment. We also revised our academic calendar and rolled out a carefully planned emergency remote teaching and learning methodology.

It is encouraging to know that you began with online learning this week. Early indications are that the Transition and Orientation from 20 to 30 April 2020 worked well in preparing you for the online learning that started on 4 May 2020. It is also good to know that the #UFSLearnOn material helped you to get ready for the start of online academic activities. Be assured that your lecturers are working hard to deliver a quality teaching and learning experience in the current circumstances. Just as this is a new experience for you, it is also a new learning experience for your lecturers. You may still experience some challenges with your academics as we complete the first week of online learning. Please contact your lecturers and/or faculties so that we can find solutions for you. You can also visit the Digital Life Portal (under the Student Toolbox) on the KovsieLife website.

You have been away from your lecturers, friends, familiar surroundings, and campus facilities for a long time, and I know that you miss it. Unfortunately, the university is bound by Level 4 restrictions and it is not possible to allow any students back on our campuses until so directed by the national government. Only final-year MB ChB students are allowed to return to campus next week – as per the directive from the national government. The majority of staff are also working from home until otherwise indicated, and in accordance with national directives for the further easing of lockdown restrictions.

This is not a university decision but is prescribed in terms of national regulations. Be assured that the university has taken adequate measures to ensure the safety of all facilities, assets, and private belongings on the campuses. We will let you know as soon as we receive a directive that students may be allowed on campus – this will be done in a phased approach in order to contain the spread of COVID-19.

Your safety, health, and well-being remain our first priority. Look after yourself and your mental health – make use of the #WellnessWarriors campaign of our Department of Student Counselling and Development that is aimed at encouraging health and well-being among students.

Please remember to regularly check the official communication platforms to stay up to date with developments at the university. Avoid fake news, verify information, and only consult the official communication platforms. 

Obeying the lockdown restrictions is an act of kindness to yourself and to others; #StayAtHome and practise social distancing.

I wish you all the best with your studies and hope to see you on our campuses soon.


Best regards

Prof Francis Petersen
Rector and Vice-Chancellor


News Archive

Nuclear Medicine on the forefront of cancer research
2017-07-10

Description: Nuclear Medicine on the forefront of cancer research Tags: Nuclear Medicine, cancer research, Dr Je’nine Horn-Lodewyk’s, tumour detection method, cancer, Department of Nuclear Medicine 

Dr Je’nine Horn-Lodewyk’s tumour detection method
could be the cost-effective breakthrough needed to decrease
the mortality rate in breast cancer patients.
Photo: Anja Aucamp

The field of Nuclear Medicine in South Africa and the rest of the world are expanding rapidly due to the development of hybrid cameras and new radiopharmaceuticals. These developments have a huge impact on the diagnosis and therapy of cancer.

The most advanced of these cameras, Positron emission tomography combined with normal CTs (PETCT), are not yet widely available in South Africa due to the cost of the cameras and the radiopharmaceuticals. A more cost-effective alternative can be of great benefit. To achieve this, the focus should be on developing new radiopharmaceuticals that can be used with the current cost-effective gamma cameras, according to University of the Free State researcher, Dr Je’nine Horn-Lodewyk from the Department of Nuclear Medicine.

Fluorodeoxyglucose (18F-FDG), a radiolabelled glucose analogue, is currently the radiopharmaceutical most commonly used in PET/CT imaging for mainly oncology indications. Although it is considered the gold standard for imaging in several malignancies, it does have certain disadvantages. An 18F-FDG PET/CT diagnostic imaging study can cost between R25 000 and R35 000 for a single patient in the private sector. The 18F-FDG is also more radioactive, which requires much stricter handling and shielding to avoid high radiation dosages to staff and patients.

Successful research potential innovative solution
In the search for the ideal radiopharmaceutical for tumour detection, the South African National Nuclear Energy Corporation (Necsa) developed a local synthesis process for ethylenedicysteine-deoxyglucose (EC-DG). EC-DG is also a glucose analogue similar to FDG. They succeeded in labelling the compound with Technetium-99-metastable-pertechnetate (99mTcO4-), the most common nuclear medicine isotope used for approximately 95% of nuclear medicine procedures, creating 99mTc-EC-DG.

In partnership with Dr Horn-Lodewyk, this compound was successfully used in various animal models and clinical scenarios, resulting in approval by the Medicine Control Council to use it in a human study. Research is also planned in order to investigate diagnostic accuracy in other cancers like lymphoma.  The end result of this research can produce a radiopharmaceutical that is cost effective, does not require the use of costly specialised equipment, has no significant side-effects, no special patient preparation, renders late imaging possible, and has decreased radiation risks.

Dr Horn-Lodewyk is grateful for the support of her mentor, Prof Anton Otto, as well as Dr Gert Engelbrecht, Head of the Department of Nuclear Medicine, Prof Jan Rijn Zeevaart from North-West University’s Preclinical Drug Development Platform and Necsa, and Judith Wagener from Necsa. This innovative research would also not have been possible without the financial assistance of Dr Glen Taylor and Eleanor van der Westhuizen in the Directorate of Research Development.

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