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12 May 2020 | Story Andre Damons | Photo Pexels

A data scientist and research coordinator at the University of the Free State (UFS), in collaboration with his supervisor at the University of Pretoria (UP), is at the forefront of the fight against the Covid-19 virus with accurate data and analysis.
Herkulaas Combrink of the Centre for Teaching and Learning at the UFS and PhD candidate in Computer Science at the UP, said accurate data is important to prevent widespread panic and sensationalism during a global disaster such as the current pandemic. This information helps people to make informed decisions and to reduce their exposure to the threat of the virus.

Assisting decision-makers

“I, along with colleagues from the World Health Organization, the Centers for Disease Control and Prevention in the USA, the provincial office of the Centers for Disease Control and Prevention, provincial clinicians, and the Free State Department of Health led by Dr David Motau, have been able to progress significantly in terms of evidence-based tools to assist provincial and national decision-makers during these turbulent times.”
“It does come at a cost, though, in that we have worked continuously since the lockdown, dedicating all our time and efforts to the department from all over to ensure that we are not part of some of the global statistics we have seen,” said Combrink. 

A paper written together with his supervisor, Dr Vukosi Marivate, has also been accepted by the Department of Higher Education and Training (DHET)-accredited Data Science Journal.  This paper is related to a framework for sharing public data to the public in a way that is useful, usable, and understandable. 

Ongoing projects

Combrink said it is hard to name all those who are/were involved in the great work done by the Free State Department of Health, but some of them include Dr Elizabeth Reji (Head of Department, Family Medicine), Dr Collin Noel (surgeon, senior lecturer at the UFS), Dr Sammy Mokoena (community health registrar, UFS), Dr Ming-Han Motloung (public health medicine specialist, senior lecturer, UFS), Dr Perpetual Chikobvu (Director: Information Management at the Department of Health, affiliated lecturer at the UFS), as well as Alfred Deacon (lecturer at the UFS), who have worked at some point during this short space of time on one of the many projects. 

Some of the projects include the following:

• A provincial database for screening and monitoring.
• A data pipeline and assembly of hospital information flow, liaised with the NICD, Vodacom, and the different district managers to ensure that the pipeline occurs in a timely manner.
• Digitised paper-based capturing tools for rapid data capturing and processing.
• Incorporated state-of-the-art visualisation tools to action data into useful information for decision-makers in certain areas.
• Provided both provincial and national projections, stress testing different scenarios using a variety of statistical, computational, and/or machine-learning approaches to add to the already existing projections of the Council for Scientific and Industrial Research (CSIR).
• Training healthcare professionals in the field to apply these tools within their own districts.
No easy task

“These aforementioned feats were by no means easy and are not completed yet, but we are getting there. In the foreseeable future, I will be working closely with national and international researchers to deploy a tool for hospital managers in the Free State that will assist them when we move from level 5 to any level below.”

“In addition to this, I am constantly providing support to the Free State Department of Health regarding any analysis required for decision-making purposes. The teams we work in comprise highly competent individuals with a passion for solving problems from multidisciplinary perspectives,” according to Combrink.

News Archive

UFS Expert: Prof Felicity Burt investigates zoonotic and arboviruses
2017-12-13


 Description: Burt read more 2 Tags: Arboviruses, Felicity Burt, Crimean-Congo haemorrhagic fever, viruses  

Prof Felicity Burt recently received a B-rating from the
National Research
Foundation.
Photo: Sonia Small

Prof Felicity Burt is from the Division of Virology in the Faculty of Health Sciences at the University of the Free State (UFS), as well as the National Health Laboratory Services (NHLS). She currently holds an NRF-DST South African Research Chair in vector-borne and zoonotic diseases.  Professor Burt and her research group investigate arboviruses and zoonotic viruses. 

Prof Burt’s research primarily focuses on host immune responses to arboviral infections specifically characterising humoral and cellular immune responses in patients with infections such as Crimean-Congo haemorrhagic fever (CCHF) virus and Sindbis virus; epitope discovery for development of diagnostic tools; development of molecular and serological assays for surveillance purposes; virus discovery; and the development of vaccines.

Raising awareness of these viruses, defining associated diseases, and developing tools for surveillance programmes will contribute to understanding these pathogens as well as the public health implications.

Leads research group in papilloma viruses
Arboviruses cause outbreaks of disease in South Africa annually. Outbreaks are usually associated with heavy rainfall favouring the breeding of mosquitos, but these viruses also have the capacity to spread and become endemic in new areas where competent vectors are present. 
In addition, she is leading a research group that investigates human papilloma viruses (HPV) associated with head and neck cancers and recurrent laryngeal papilloma.

The focus of this research group is to ascertain the genotypes of HPV causing these diseases, identification of novel biomarkers for early detection, and complete genome sequencing for molecular characterisation of HPV isolates.  

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