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09 October 2020 Photo Supplied
Kgalalelo Motlhabane
A Master of Commerce degree with specialisation in Industrial Psychology will be conferred on Kgalalelo Motlhabane, a graduate and funding officer at the Postgraduate School at UFS on Friday 9 October 2020 in a virtual graduation.

One of the success stories of this year’s virtual graduation is Kgalalelo Motlhabane, a graduate and funding officer at the Postgraduate School, University of the Free State (UFS), who was presented with an award from the National Research Foundation as the best designated authority for 2019.

Motlhabane, who lost her mother when she was in high school, didn’t just have to overcome poverty on her way to her first qualification, but also the fear of ending up on the street. On Friday 9 October she received a Master of Commerce degree with specialisation in Industrial Psychology.

A lot of challenges

“I had a lot of challenges during my first-year undergraduate studies. I could not afford textbooks and stationery. I spent most of my time in the library studying. More often I would be without food and proper clothes to wear.

“I would get warnings from my landlord when the rent was late. Sometimes I would find my room locked and my personal stuff removed. Not being able to pay outstanding fees restricted me from receiving my final results at the end of semesters and exacerbated the situation,” says Motlhabane.

Regardless of all these challenges, she was determined to not give up and return home to the impoverished community of Itireleng village near Pampierstad in the Northern Cape.

Overcoming the challenges

It was actually the distress, poverty and the difficult situation at home, together with her daily struggles that kept her focused. Through hard work, she managed to receive funding from NSFAS for her second and third years and despite the hardships, she obtained her BSocSci degree with distinction at the end of 2012.

“I was then selected to enroll for an Honours degree in Industrial Psychology in 2013. Without any funding prospects for my studies, I wrote to the former university rector Prof Jonathan Jansen, seeking financial assistance.

“Prof Jansen was very impressed with my exceptional academic performance and offered to pay my fees. He also offered me a position to work as a student assistant. I worked for three hours every day before going to the library to do my assignments and prepare for classes, presentations, tests and exams. I completed my Honours degree in 2013.”

In 2014, Motlhabane was employed as an intern at the UFS Human Resources Department and also enrolled for a postgraduate diploma in gender studies, which she obtained at the end of that year. The following year she joined the postgraduate school and started with her Master’s degree in late 2016.

Obtaining a Master’s degree

This was no easy task as she was employed full time which left her with little time to work thoroughly on her thesis, her limited knowledge about research, work pressures and demands, rejections, lack of support, discouragements, accidents and the inability to cope also played a role.  

“I would like to thank God for the strength he gave me to cope throughout my journey, my family for their prayers and continued support, as well as Prof Jonathan Jansen, Prof Petrus Nel and Prof Ebben van Zyl for their kind support and contribution towards my studies. Indeed, the future belongs to those who believe in the beauty of their dreams,” says Motlhabane.

News Archive

Nuclear Medicine on the forefront of cancer research
2017-07-10

Description: Nuclear Medicine on the forefront of cancer research Tags: Nuclear Medicine, cancer research, Dr Je’nine Horn-Lodewyk’s, tumour detection method, cancer, Department of Nuclear Medicine 

Dr Je’nine Horn-Lodewyk’s tumour detection method
could be the cost-effective breakthrough needed to decrease
the mortality rate in breast cancer patients.
Photo: Anja Aucamp

The field of Nuclear Medicine in South Africa and the rest of the world are expanding rapidly due to the development of hybrid cameras and new radiopharmaceuticals. These developments have a huge impact on the diagnosis and therapy of cancer.

The most advanced of these cameras, Positron emission tomography combined with normal CTs (PETCT), are not yet widely available in South Africa due to the cost of the cameras and the radiopharmaceuticals. A more cost-effective alternative can be of great benefit. To achieve this, the focus should be on developing new radiopharmaceuticals that can be used with the current cost-effective gamma cameras, according to University of the Free State researcher, Dr Je’nine Horn-Lodewyk from the Department of Nuclear Medicine.

Fluorodeoxyglucose (18F-FDG), a radiolabelled glucose analogue, is currently the radiopharmaceutical most commonly used in PET/CT imaging for mainly oncology indications. Although it is considered the gold standard for imaging in several malignancies, it does have certain disadvantages. An 18F-FDG PET/CT diagnostic imaging study can cost between R25 000 and R35 000 for a single patient in the private sector. The 18F-FDG is also more radioactive, which requires much stricter handling and shielding to avoid high radiation dosages to staff and patients.

Successful research potential innovative solution
In the search for the ideal radiopharmaceutical for tumour detection, the South African National Nuclear Energy Corporation (Necsa) developed a local synthesis process for ethylenedicysteine-deoxyglucose (EC-DG). EC-DG is also a glucose analogue similar to FDG. They succeeded in labelling the compound with Technetium-99-metastable-pertechnetate (99mTcO4-), the most common nuclear medicine isotope used for approximately 95% of nuclear medicine procedures, creating 99mTc-EC-DG.

In partnership with Dr Horn-Lodewyk, this compound was successfully used in various animal models and clinical scenarios, resulting in approval by the Medicine Control Council to use it in a human study. Research is also planned in order to investigate diagnostic accuracy in other cancers like lymphoma.  The end result of this research can produce a radiopharmaceutical that is cost effective, does not require the use of costly specialised equipment, has no significant side-effects, no special patient preparation, renders late imaging possible, and has decreased radiation risks.

Dr Horn-Lodewyk is grateful for the support of her mentor, Prof Anton Otto, as well as Dr Gert Engelbrecht, Head of the Department of Nuclear Medicine, Prof Jan Rijn Zeevaart from North-West University’s Preclinical Drug Development Platform and Necsa, and Judith Wagener from Necsa. This innovative research would also not have been possible without the financial assistance of Dr Glen Taylor and Eleanor van der Westhuizen in the Directorate of Research Development.

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