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08 October 2020 | Story Leonie Bolleurs | Photo Supplied
Dr Cornel Bender
Dr Cornel Bender received her PhD qualification at the virtual graduation ceremonies in October. The title of her thesis is: Stem rust resistance in South African wheat and triticale.

The rapid distribution of disease-causing organisms such as Ug99, a wheat stem-rust pathotype, pointed out just how vulnerable global cereal production is to disease outbreaks.

These cereals include wheat, barley, rye, oats, triticale, rice, maize, and millet and are one of the most important food sources for human consumption.

According to Dr Cornel Bender, the projected world population of 10 billion in 2057 requires a growth of more than 40% in cereal production. Wheat is grown on more hectares than any other cereal and is one of the most important sources of calories for humans. However, the growth rate of wheat yields has declined from the 1960s to the 1990s. Therefore, it is essential to increase global wheat production.

“With the regular appearance of more aggressive stem rust pathotypes in South Africa, there is a constant need to discover new sources of resistance, understand the genetic base of presently deployed sources in wheat, triticale and barley cultivars, and to manipulate the deployment of resistant sources through a more sustainable approach,” says Dr Bender.

Her PhD thesis, titled: Stem rust resistance in South African wheat and triticale, includes various fundamental aspects for the effective management of stem rust in South Africa.

Dr Bender is a Professional Officer in the Division of Plant Pathology in the Department of Plant Sciences, who received her PhD at the virtual graduation ceremonies in October.

Innovative and cost effective

Her promotors, Prof Zakkie Pretorius, Research Fellow, and Dr Willem Boshoff, Senior Lecturer in the Department of Plant Sciences, believe that she used an innovative approach to develop a cost-effective phenotyping method to select for more durable resistance types in a controlled greenhouse environment.

“In the past, results obtained from field trials used to assess adult plants for stem-rust resistance, were often influenced by abiotic factors, were seasonable in nature, expensive, and time consuming; therefore, the development of a dependable greenhouse screening system provides an important additional instrument for rust research,” says Dr Bender.

She adds that the greenhouse technique is used worldwide to screen for adult plant resistance and contribute to save time and money.

Broadening our knowledge

“Inheritance studies were undertaken to determine the genetic base of stem-rust resistance in selected South African wheat and triticale cultivars (developed from wheat/rye crosses) through seedling analysis as well as greenhouse and fieldwork,” she says.

Dr Bender believes the use and development of different resistance screening methods, the elucidation of host genetics, as well as the use of histological and microscopic methods to study early resistance responses, broaden our knowledge and understanding of stem-rust resistance in South African wheat and triticale cultivars.

Ultimately, rust researchers, grain producers, and also the general public – through access to their daily bread – will benefit from her study.

News Archive

UFS cardiologists and surgeons give children a beating heart
2015-04-23

Photo: René-Jean van der Berg

A team from the University of the Free State School for Medicine work daily unremittingly to save the lives of young children who have been born with heart defects by carrying out highly specialised interventions and operations on them. These operations, which are nowadays performed more and more frequently by cardiologists from the UFS School of Medicine, place the UFS on a similar footing to world-class cardiology and cardio-thoracic units.

One of the children is seven-month-old Montsheng Ketso who recently underwent a major heart operation to keep the left ventricle of her heart going artificially.

Montsheng was born with a rare, serious defect of the coronary artery, preventing the left ventricle from receiving enough blood to pump to the rest of the body.

This means that the heart muscle can suffer damage because these children essentially experience a heart attack at a very young age.

In a healthy heart, the left ventricle receives oxygenated blood from the left atrium. Then the left ventricle pumps this oxygen-rich blood to the aorta whence it flows to the rest of the body. The heart muscle normally receives blood supply from the oxygenated aorta blood, which in this case cannot happen.

Photo: René-Jean van der Berg

“She was very ill. I thought my baby was going to die,” says Mrs Bonizele Ketso, Montsheng’s mother.

She says that Montsheng became sick early in February, and she thought initially it was a tight chest or a cold. After a doctor examined and treated her baby, Montsheng still remained constantly ill, so the doctor referred her to Prof Stephen Brown, paediatric cardiologist at the UFS and attached to Universitas Hospital.

Here, Prof Brown immediately got his skilled team together as quickly as possible to diagnose the condition in order to operate on Montsheng.

During the operation, the blood flow was restored, but since Montsheng’s heart muscle was seriously damaged, the heart was unable to contract at the end of the operation. Then she was coupled to a heart-lung machine to allow the heart to rest and give the heart muscle chance to recover. The entire team of technologists and the dedicated anaesthetist, Dr Edwin Turton, kept a vigil day and night for several days.

Prof Francis Smit, chief specialist at the UFS Department of Cardiothoracic Surgery, explains that without this operation Montsheng would not have been able to celebrate her first birthday.

“After the surgery, these children can reach adulthood without further operations. Within two to three months after the operation, she will have a normal active life, although for about six months she will still use medication. Thereafter, she will be tiptop and shortly learn to crawl and walk.”

Mrs Ketso is looking forward enormously to seeing her daughter stand up and take her first steps. A dream which she thought would never come true.    

“Write there that I really love these doctors.”

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