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16 October 2020 | Story Leonie Bolleurs | Photo Supplied
Kyla Dooley, runner-up in this year’s Three-minute thesis competition, wants to pursue a career working alongside police enforcement, using her knowledge of forensics to solve criminal cases and convict perpetrators.

When rapes and sexual assaults are committed, DNA evidence can play a large role in convicting the offenders. DNA evidence collected from sexual crimes can, according to Kyla Dooley, often be tricky to analyse.

Kyla has just completed her master’s degree, specialising in Forensic Genetics, at the University of the Free State (UFS). She not only thrives in this field – graduating at the top of the Faculty of Natural and Agricultural Sciences in 2018 when she was awarded the Dean’s Medal – but her work also brought her the runner-up position in this year’s Three-minute thesis competition. 

She talked about her research on the use of male-specific DNA in the analysis of DNA evidence collected after crimes of a sexual nature have been committed.

Explaining her research, Kyla elaborates: “In most cases, the victim is female, while the offender is male. Therefore, the evidence is often a mixture of male and female DNA and this can make it difficult to analyse the male DNA and match it to a male suspect.”

She believes the solution to this is to target male-specific DNA in analysis. “This eliminates all female DNA and simplifies the process,” says Kyla.

“Unfortunately, male-specific DNA technology is not currently used in South Africa, because the DNA regions tested to date haven’t shown much success in distinguishing between males in our population,” Kyla points out.

“The goal is now to use DNA evidence, to match it to a suspect, and have the confidence that it came from him and only him. Or else defence lawyers could argue that it came from someone else in the population,” she says.

Improving DNA evidence

Therefore, Kyla’s research focused on evaluating a new group of male-specific DNA regions, which are to be tested yet, to see if it would be a viable option for use in South Africa. 

“I achieved this by collecting DNA samples from men on campus, processing them to obtain DNA profiles, and then determining how well these regions can distinguish between the men. The results of my research demonstrate the potential of these DNA regions to improve the use of DNA evidence when investigating sexual assaults in South Africa,” says Kyla.

She believes her study can play a role in increasing the conviction rate of sexual offenders, which could lead to a reduction in South Africa’s alarmingly high rape statistic. 

“Everyone in South Africa is affected by this horrific crime in some way or another, so the benefits of this would be widespread,” she says.

Solving crimes

Although Kyla will one day pursue further studies, she is ready for the next stage in her life. “I am in the process of applying for jobs and getting ready to dive into the real world. I’ll definitely be pursuing a career working alongside police enforcement to solve criminal cases and convict perpetrators of such crimes. Working for the NYPD in the USA or Scotland Yard in the UK is the ultimate dream job,” she says.

“I chose my field not only because the forensics world absolutely fascinates me, but also because I want to make a difference. I want to play a role in getting justice for those affected by violent crimes. One simple process in a forensic scientist’s everyday routine could be a life changer for a victim of crime,” believes Kyla.

 

 


News Archive

#Women'sMonth: Lack of HIV education still affects children
2017-08-17

Description: Nickie Goedhals Tags: Dr Nickie Goedhals, Medical Microbiology and Virology, The Lancet, transmission of HIV, National Research Foundation 

Dr Nickie Goedhals, Senior Lecturer and Pathologist
in Medical Microbiology and Virology at the UFS.
Photo: Sonia Small



“Despite all the advances in the management and prevention of HIV, children still become infected every day, often due to lack of education and access to health care.” This is according to Dr Nickie Goedhals, Senior Lecturer and Pathologist in Medical Microbiology and Virology at the University of the Free State (UFS).

Study published in UK medical Journal 
A case study she was part of and published in the UK medical journal The Lancet in 2012, demonstrates the transmission of HIV to a child through surrogate breastfeeding. This study is one of the many highlights in the young researcher’s career. She received her first rating from the National Research Foundation (NRF) in 2017 for the work she has done in Medical Virology over the past eight years.

According to the above-mentioned study, only about 1% of infants in South Africa are being breastfed by a surrogate. However, results from a study in the Free State showed that shared breastfeeding by a non-biological caregiver was the most important factor associated with HIV infection in discordant mother-child pairs. Therefore, continued education about the risk of HIV transmission is needed.

Dr Goedhals is also continuing with research on HIV by looking at HIV drug resistance. She is in the process of starting new projects focusing on HIV infection and drug resistance in infants.

PSP helped with NRF-rating
She says, although her NRF Y2-rating is the starting point of a research career, it shows that she is heading in the right direction, and it “gives access to research funds through the NRF for future projects.” Other important research she conducted was on Crimean-Congo haemorrhagic fever – the study for her PhD.

The Prestige Scholars Programme (PSP) at the UFS is the reason that she applied for the rating. “With all the service delivery, teaching, and administrative responsibilities of academic medicine, it is easy to lose focus. The PSP has really helped to create a focused and stimulating environment for research.” According to her, the PSP also provides access to a network of peers and senior staff at the UFS, as well as exposure to national and international experts.

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