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16 October 2020 | Story Leonie Bolleurs | Photo Supplied
Kyla Dooley, runner-up in this year’s Three-minute thesis competition, wants to pursue a career working alongside police enforcement, using her knowledge of forensics to solve criminal cases and convict perpetrators.

When rapes and sexual assaults are committed, DNA evidence can play a large role in convicting the offenders. DNA evidence collected from sexual crimes can, according to Kyla Dooley, often be tricky to analyse.

Kyla has just completed her master’s degree, specialising in Forensic Genetics, at the University of the Free State (UFS). She not only thrives in this field – graduating at the top of the Faculty of Natural and Agricultural Sciences in 2018 when she was awarded the Dean’s Medal – but her work also brought her the runner-up position in this year’s Three-minute thesis competition. 

She talked about her research on the use of male-specific DNA in the analysis of DNA evidence collected after crimes of a sexual nature have been committed.

Explaining her research, Kyla elaborates: “In most cases, the victim is female, while the offender is male. Therefore, the evidence is often a mixture of male and female DNA and this can make it difficult to analyse the male DNA and match it to a male suspect.”

She believes the solution to this is to target male-specific DNA in analysis. “This eliminates all female DNA and simplifies the process,” says Kyla.

“Unfortunately, male-specific DNA technology is not currently used in South Africa, because the DNA regions tested to date haven’t shown much success in distinguishing between males in our population,” Kyla points out.

“The goal is now to use DNA evidence, to match it to a suspect, and have the confidence that it came from him and only him. Or else defence lawyers could argue that it came from someone else in the population,” she says.

Improving DNA evidence

Therefore, Kyla’s research focused on evaluating a new group of male-specific DNA regions, which are to be tested yet, to see if it would be a viable option for use in South Africa. 

“I achieved this by collecting DNA samples from men on campus, processing them to obtain DNA profiles, and then determining how well these regions can distinguish between the men. The results of my research demonstrate the potential of these DNA regions to improve the use of DNA evidence when investigating sexual assaults in South Africa,” says Kyla.

She believes her study can play a role in increasing the conviction rate of sexual offenders, which could lead to a reduction in South Africa’s alarmingly high rape statistic. 

“Everyone in South Africa is affected by this horrific crime in some way or another, so the benefits of this would be widespread,” she says.

Solving crimes

Although Kyla will one day pursue further studies, she is ready for the next stage in her life. “I am in the process of applying for jobs and getting ready to dive into the real world. I’ll definitely be pursuing a career working alongside police enforcement to solve criminal cases and convict perpetrators of such crimes. Working for the NYPD in the USA or Scotland Yard in the UK is the ultimate dream job,” she says.

“I chose my field not only because the forensics world absolutely fascinates me, but also because I want to make a difference. I want to play a role in getting justice for those affected by violent crimes. One simple process in a forensic scientist’s everyday routine could be a life changer for a victim of crime,” believes Kyla.

 

 


News Archive

Nobel Laureate for Chemistry to visit UFS
2017-10-28

Description: Prof Levitt read more Tags: Prof Levitt read more

Prof Michael Levitt will be hosted by the UFS from
14 to 16 November 2017, where he will present the
first lecture in the Vice-Chancellor’s
Prestige Lecture Series.
Photo: Supplied

It is a great honour for the University of the Free State (UFS) to host Prof Michael Levitt, recipient of the 2013 Nobel Prize for Chemistry, which he shares with Marti Karplus and Arieh Warshel.

The trio received the Nobel Prize for their development of multiscale models used for complex chemical systems. “Being awarded the Nobel Prize is a unique and marvellous experience that no one can prepare for or could in any way know what to except,” said Prof Levitt during his 2013 Nobel Lecture at the Stanford University School of Medicine.

First lecture in Vice-Chancellor’s lecture series

The South African-born Nobel Laureate and Academy of Science of South Africa (ASSAf) Visiting Scholar will present the first lecture, Birth and Future of Multiscale Modelling of Macromolecules, in the Vice-Chancellors Prestige Lecture Series at the UFS on 14 November 2017. Prof Levitt is well-known for developing approaches which predict macromolecular structures.

He is one of many distinguished academics invited annually by ASSAf to deliver lectures as part of the Distinguished Visiting Scholars’ Programme, presented by ASSAf at universities across the country.

Pioneer in research of molecular dynamics

Prof Levitt is a biophysicist and a professor of Biology at Stanford University. He was one of the earliest researchers to conduct research on molecular dynamics stimulations of DNA and proteins. “My post-prize ambitions are twofold and probably inconsistent: (1) Work single-mindedly as I did in the mid-1970s on hard problems, and (2) Help today’s young scientists gain the recognition and independence which my generation enjoyed,” said Prof Levitt.

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