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16 October 2020 | Story Leonie Bolleurs | Photo Supplied
Kyla Dooley, runner-up in this year’s Three-minute thesis competition, wants to pursue a career working alongside police enforcement, using her knowledge of forensics to solve criminal cases and convict perpetrators.

When rapes and sexual assaults are committed, DNA evidence can play a large role in convicting the offenders. DNA evidence collected from sexual crimes can, according to Kyla Dooley, often be tricky to analyse.

Kyla has just completed her master’s degree, specialising in Forensic Genetics, at the University of the Free State (UFS). She not only thrives in this field – graduating at the top of the Faculty of Natural and Agricultural Sciences in 2018 when she was awarded the Dean’s Medal – but her work also brought her the runner-up position in this year’s Three-minute thesis competition. 

She talked about her research on the use of male-specific DNA in the analysis of DNA evidence collected after crimes of a sexual nature have been committed.

Explaining her research, Kyla elaborates: “In most cases, the victim is female, while the offender is male. Therefore, the evidence is often a mixture of male and female DNA and this can make it difficult to analyse the male DNA and match it to a male suspect.”

She believes the solution to this is to target male-specific DNA in analysis. “This eliminates all female DNA and simplifies the process,” says Kyla.

“Unfortunately, male-specific DNA technology is not currently used in South Africa, because the DNA regions tested to date haven’t shown much success in distinguishing between males in our population,” Kyla points out.

“The goal is now to use DNA evidence, to match it to a suspect, and have the confidence that it came from him and only him. Or else defence lawyers could argue that it came from someone else in the population,” she says.

Improving DNA evidence

Therefore, Kyla’s research focused on evaluating a new group of male-specific DNA regions, which are to be tested yet, to see if it would be a viable option for use in South Africa. 

“I achieved this by collecting DNA samples from men on campus, processing them to obtain DNA profiles, and then determining how well these regions can distinguish between the men. The results of my research demonstrate the potential of these DNA regions to improve the use of DNA evidence when investigating sexual assaults in South Africa,” says Kyla.

She believes her study can play a role in increasing the conviction rate of sexual offenders, which could lead to a reduction in South Africa’s alarmingly high rape statistic. 

“Everyone in South Africa is affected by this horrific crime in some way or another, so the benefits of this would be widespread,” she says.

Solving crimes

Although Kyla will one day pursue further studies, she is ready for the next stage in her life. “I am in the process of applying for jobs and getting ready to dive into the real world. I’ll definitely be pursuing a career working alongside police enforcement to solve criminal cases and convict perpetrators of such crimes. Working for the NYPD in the USA or Scotland Yard in the UK is the ultimate dream job,” she says.

“I chose my field not only because the forensics world absolutely fascinates me, but also because I want to make a difference. I want to play a role in getting justice for those affected by violent crimes. One simple process in a forensic scientist’s everyday routine could be a life changer for a victim of crime,” believes Kyla.

 

 


News Archive

Doctors make history with unique heart operation
2012-04-04

 

Cardiologists at the university delivered the first Melody pulmonary valve in Africa.
Photo: Evert Kleynhans
30 March 2012

Academics of the Faculty of Health Sciences at the University of the Free State made history in Africa once again this week with the implant of a special pulmonary heart valve.

“Today we are extremely proud Free State citizens,” Prof. Stephen Brown and Dr. Danie Buys from the UFS Department of Paediatrics and Child Health said after they placed the Medtronic Melody pulmonary valve in two young patients at the Universitas hospital in Bloemfontein.

This is the first time in Africa that the Melody valve is placed.

To date there are currently only 3 000 of these valves place in the world.

“It feels incredible to be part of a team of experts from the faculty.”

The Medtronic Melody valve is delivered percutaneously through a catheter from the groin. This operation is for children and young adults who are born with a malformation of their pulmonary valve.

These children often require open-heart surgery at a very young age and later require additional open-heart surgeries to restore blood flow between the heart and the lungs.

Prof. Brown said that of all congenital diseases, heart disease is most common. A lot of children born with heart disease are diagnosed very late and many die without ever receiving specialised care.

In 2011, Prof. Brown and two other cardiologists from the UFS, Prof. Hennie Theron en Dr JP Theron also reached a medical milestone when they were the first cardiologists in South Africa to do a second generation Medtronic CoreValve implant on an elderly patient.
 

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