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23 October 2020 | Story Andre Damons | Photo Supplied
Dr Potgieter and her team from Beanies4Babies are with women from Westerbloem retirement village, who knit the beanies and socks.

A passion for neonates, especially premature babies, led to an alumna from the University of the Free State (UFS) to co-found Beanies4Babies, an NPO  which provides knitted beanies and socks to all babies admitted to the newborn intensive care unit (NICU) in public hospitals.
Dr Johané Potgieter, a first-year medical intern and co-founder of Beanies4babies, says neonates, especially premature babies, are unable to generate their own heat, and thus are dependent of additional measures to warm them. They have a larger head-to-body surface area which increases their risk for heat loss if the head is not covered. 
According to Dr Potgieter these little miracles have to use all their energy to grow stronger and fight infection instead of generating heat to prevent them from getting too cold. During her studies she was fortunate to learn vital lessons from passionate and vibrant doctors and sisters. One of them, Sr Vanessa Booysen, lit the fire in her heart for neonates, more specifically premature babies, she says.
Need to prevention hypothermia in premature babies and neonates
The dream started in 2018, when she was a 4th-year medical student, doing her first call in the NICU at Pelonomi Tertiary Hospital. “I noticed the need for additional measures to prevent hypothermia in neonates and was eager to actively combat it. I had an amazing idea for a new project, which sadly had little support. I shared my thoughts with my friend, now co-founder, Clarette Cronje.”
“It was challenging, everyone thought this was going to be a once-off donation. However, I knew my dream was too big for limitations like this. After numerous attempts and failures, a door finally opened to liaise with the Mother and Child Academic Hospital (MACAH) Foundation. As they say: ‘Fall seven times, stand up eight’,” says Dr Potgieter. 
The NPO currently provides about 300 packages of knitted beanies and socks a month to all neonates admitted to the NICU in the public hospitals in Bloemfontein and Port Elizabeth. 
The aim is to expand the project nationwide, and according to Dr Potgieter, they are also are launching it in January at Charlotte Maxeke Johannesburg Academic Hospital, where she now works. 
A need exists 
Dr Potgieter says they had always trusted and hoped for something that would change lives but had never imagined it would be on such a scale.  
“There is a need for beanies and socks for these premature babies. We come face to face with this daily and have only scratched the surface. Global statistics for premature births are one in every 10 births. National statistics are one in every seven births. 
“Premature and newborn babies cannot generate their own heat through shivering or adding additional layers of clothing to their skin. They are exposed to the surrounding air and objects, increasing their risk for heat loss. They lose a great deal of heat from their heads, making it of critical importance to cover their heads. A large number of our mothers go into premature labour, with an earlier due date than planned, arriving in an ambulance without a newborn’s clothes. So it is clear that a bigger hand is driving this project,” says Dr Potgieter. 
Also involve the elderly
Beanies4Babies not only focuses on supporting neonates, but also involves the elderly in the community who knit the products for project. “The angels at the old age homes eagerly knit away. But they need wool. Donations for wool and packaging are needed to service hospitals in three provinces (Free State, Eastern Cape and Gauteng).”
“Volunteers and financial support are also needed as operations have been scaled up to ensure efficiency.”
Says Dr Potgieter: “We are privileged to have a dynamic team of doctors, students, sisters and allied health professionals who support our project.”
Beanies4Babies now functions as one of the First 1000 days projects of the MACAH Foundation that aims to optimise the future for the young generation. 
“I am blessed to have the opportunity to do what I love and that is to make a difference.” 

News Archive

Nanotechnology breakthrough at UFS
2010-08-19

 Ph.D students, Chantel Swart and Ntsoaki Leeuw


Scientists at the University of the Free State (UFS) made an important breakthrough in the use of nanotechnology in medical and biological research. The UFS team’s research has been accepted for publication by the internationally accredited Canadian Journal of Microbiology.

The UFS study dissected yeast cells exposed to over-used cooking oil by peeling microscopically thin layers off the yeast cells through the use of nanotechnology.

The yeast cells were enlarged thousands of times to study what was going on inside the cells, whilst at the same time establishing the chemical elements the cells are composed of. This was done by making microscopically small surgical incisions into the cell walls.

This groundbreaking research opens up a host of new uses for nanotechnology, as it was the first study ever in which biological cells were surgically manipulated and at the same time elemental analysis performed through nanotechnology. According to Prof. Lodewyk Kock, head of the Division Lipid Biotechnology at the UFS, the study has far reaching implications for biological and medical research.

The research was the result of collaboration between the Department of Microbial, Biochemical and Food Biotechnology, the Department of Physics (under the leadership of Prof. Hendrik Swart) and the Centre for Microscopy (under the leadership of Prof.Pieter van Wyk).

Two Ph.D. students, Chantel Swart and Ntsoaki Leeuw, overseen by professors Kock and Van Wyk, managed to successfully prepare yeast that was exposed to over-used cooking oil (used for deep frying of food) for this first ever method of nanotechnological research.

According to Prof. Kock, a single yeast cell is approximately 5 micrometres long. “A micrometre is one millionth of a metre – in laymen’s terms, even less than the diameter of a single hair – and completely invisible to the human eye.”

Through the use of nanotechnology, the chemical composition of the surface of the yeast cells could be established by making a surgical incision into the surface. The cells could be peeled off in layers of approximately three (3) nanometres at a time to establish the effect of the oil on the yeast cell’s composition. A nanometre is one thousandth of a micrometre.

Each cell was enlarged by between 40 000 and 50 000 times. This was done by using the Department of Physics’ PHI700 Scanning Auger Nanoprobe linked to a Scanning Electron Microscope and Argon-etching. Under the guidance of Prof. Swart, Mss. Swart en Leeuw could dissect the surfaces of yeast cells exposed to over-used cooking oil. 

The study noted wart like outgrowths - some only a few nanometres in diameter – on the cell surfaces. Research concluded that these outgrowths were caused by the oil. The exposure to the oil also drastically hampered the growth of the yeast cells. (See figure 1)  

Researchers worldwide have warned about the over-usage of cooking oil for deep frying of food, as it can be linked to the cause of diseases like cancer. The over-usage of cooking oil in the preparation of food is therefore strictly regulated by laws worldwide.

The UFS-research doesn’t only show that over-used cooking oil is harmful to micro-organisms like yeast, but also suggests how nanotechnology can be used in biological and medical research on, amongst others, cancer cells.

 

Figure 1. Yeast cells exposed to over-used cooking oil. Wart like protuberances/ outgrowths (WP) is clearly visible on the surfaces of the elongated yeast cells. With the use of nanotechnology, it is possible to peel off the warts – some with a diameter of only a few nanometres – in layers only a few nanometres thick. At the same time, the 3D-structure of the warts as well as its chemical composition can be established.  

Media Release
Issued by: Mangaliso Radebe
Assistant Director: Media Liaison
Tel: 051 401 2828
Cell: 078 460 3320
E-mail: radebemt@ufs.ac.za  
18 August 2010
 

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