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23 October 2020 | Story Andre Damons | Photo Supplied
Dr Potgieter and her team from Beanies4Babies are with women from Westerbloem retirement village, who knit the beanies and socks.

A passion for neonates, especially premature babies, led to an alumna from the University of the Free State (UFS) to co-found Beanies4Babies, an NPO  which provides knitted beanies and socks to all babies admitted to the newborn intensive care unit (NICU) in public hospitals.
Dr Johané Potgieter, a first-year medical intern and co-founder of Beanies4babies, says neonates, especially premature babies, are unable to generate their own heat, and thus are dependent of additional measures to warm them. They have a larger head-to-body surface area which increases their risk for heat loss if the head is not covered. 
According to Dr Potgieter these little miracles have to use all their energy to grow stronger and fight infection instead of generating heat to prevent them from getting too cold. During her studies she was fortunate to learn vital lessons from passionate and vibrant doctors and sisters. One of them, Sr Vanessa Booysen, lit the fire in her heart for neonates, more specifically premature babies, she says.
Need to prevention hypothermia in premature babies and neonates
The dream started in 2018, when she was a 4th-year medical student, doing her first call in the NICU at Pelonomi Tertiary Hospital. “I noticed the need for additional measures to prevent hypothermia in neonates and was eager to actively combat it. I had an amazing idea for a new project, which sadly had little support. I shared my thoughts with my friend, now co-founder, Clarette Cronje.”
“It was challenging, everyone thought this was going to be a once-off donation. However, I knew my dream was too big for limitations like this. After numerous attempts and failures, a door finally opened to liaise with the Mother and Child Academic Hospital (MACAH) Foundation. As they say: ‘Fall seven times, stand up eight’,” says Dr Potgieter. 
The NPO currently provides about 300 packages of knitted beanies and socks a month to all neonates admitted to the NICU in the public hospitals in Bloemfontein and Port Elizabeth. 
The aim is to expand the project nationwide, and according to Dr Potgieter, they are also are launching it in January at Charlotte Maxeke Johannesburg Academic Hospital, where she now works. 
A need exists 
Dr Potgieter says they had always trusted and hoped for something that would change lives but had never imagined it would be on such a scale.  
“There is a need for beanies and socks for these premature babies. We come face to face with this daily and have only scratched the surface. Global statistics for premature births are one in every 10 births. National statistics are one in every seven births. 
“Premature and newborn babies cannot generate their own heat through shivering or adding additional layers of clothing to their skin. They are exposed to the surrounding air and objects, increasing their risk for heat loss. They lose a great deal of heat from their heads, making it of critical importance to cover their heads. A large number of our mothers go into premature labour, with an earlier due date than planned, arriving in an ambulance without a newborn’s clothes. So it is clear that a bigger hand is driving this project,” says Dr Potgieter. 
Also involve the elderly
Beanies4Babies not only focuses on supporting neonates, but also involves the elderly in the community who knit the products for project. “The angels at the old age homes eagerly knit away. But they need wool. Donations for wool and packaging are needed to service hospitals in three provinces (Free State, Eastern Cape and Gauteng).”
“Volunteers and financial support are also needed as operations have been scaled up to ensure efficiency.”
Says Dr Potgieter: “We are privileged to have a dynamic team of doctors, students, sisters and allied health professionals who support our project.”
Beanies4Babies now functions as one of the First 1000 days projects of the MACAH Foundation that aims to optimise the future for the young generation. 
“I am blessed to have the opportunity to do what I love and that is to make a difference.” 

News Archive

Research eradicates bacteria from avocado facility
2017-01-17

 Description: Listeria monocytogenes Tags: Listeria monocytogenes

Listeria monocytogenes as seen under an electron
microscope. The photo was taken with a transmission
electron microscope at the microscopy unit of the UFS.
Bacteriophages (lollipop-like structures) can be seen
next to the bacterial cells.
Photo: Supplied

“The aim of my project was to identify and characterise the contamination problem in an avocado-processing facility and then to find a solution,” said Dr Amy Strydom, postdoctoral fellow in the Department of Microbial Biochemical and Food Biotechnology at the University of the Free State (UFS).

Her PhD, “Control of Listeria monocytogenes in an Avocado-processing Facility”, aimed to identify and characterise the contamination problem in a facility where avocados were processed into guacamole. Dr Strydom completed her MSc in food science in 2009 at Stellenbosch University and this was the catalyst for her starting her PhD in microbiology in 2012 at the UFS. The research was conducted over a period of four years and she graduated in 2016. The research project was funded by the National Research Foundation.

The opportunity to work closely with the food industry further motivated Dr Strydom to conduct her research. The research has made a significant contribution to a food producer (avocado facility) that will sell products that are not contaminated with any pathogens. The public will then buy food that is safe for human consumption.


What is Listeria monocytogenes?

Listeria monocytogenes is a food-borne pathogenic bacterium. When a food product is contaminated with L. monocytogenes, it will not be altered in ways that are obvious to the consumer, such as taste and smell. When ingested, however, it can cause a wide range of illnesses in people with impaired immune systems. “Risk groups include newborn babies, the elderly, and people suffering from diseases that weaken their immune systems,” Dr Strydom said. The processing adjustments based on her findings resulted in decreased numbers of Listeria in the facility.

The bacteria can also survive and grow at refrigeration temperatures, making them dangerous food pathogens, organisms which can cause illnesses [in humans]. Dr Strydom worked closely with the facility and developed an in-house monitoring system by means of which the facility could test their products and the processing environment. She also evaluated bacteriophages as a biological control agent in the processing facility. Bacteriophages are viruses that can only infect specific strains of bacteria. Despite bacteriophage products specifically intended for the use of controlling L. monocytogenes being commercially available in the food industry, Dr Strydom found that only 26% of the L. monocytogenes population in the facility was destroyed by the ListexP100TM product. “I concluded that the genetic diversity of the bacteria in the facility was too high and that the bacteriophages could not be used as a control measure. However, there is much we do not understand about bacteriophages, and with a few adjustments, we might be able to use them in the food industry.”

Microbiological and molecular characterisation of L. monocytogenes

The bacteria were isolated and purified using basic microbiological culturing. Characterisation was done based on specific genes present in the bacterial genome. “I amplified these genes with polymerase chain reaction (PCR), using various primers targeting these specific genes,” Dr Strydom said. Some amplification results were analysed with a subsequent restriction digestion where the genes were cut in specific areas with enzymes to create fragments. The lengths of these fragments can be used to differentiate between strains. “I also compared the whole genomes of some of the bacterial strains.” The bacteriophages were then isolated from waste water samples at the facility using the isolated bacterial strains. “However, I was not able to isolate a bacteriophage that could infect the bacteria in the facility.

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