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28 October 2020 | Story Nitha Ramnath


Lunchtime learning webinar series on Interdisciplinarity in Action

Mastering a musical instrument, such as the piano, requires the simultaneous integration of a multimodal, sensory system and motor information with multimodal, sensory feedback mechanisms that continuously monitor the performance. Performing intricate movements requires complex, sensory-motor programming of finger and hand movements, which can result in a reorganisation of the brain regarding functional and structural changes of existing and the establishment of new connections. Neuronal networks involved in music processing are adaptable and fast-changing. When motor skills are simplified to the most important action, it consists of nerve impulses sent to the muscles.

In this webinar, Dr Frelét de Villiers discusses the interdisciplinarity between the two fields of music and neuroscience. Promising preliminary data has been reported for applications of transcranial direct stimulation (tDCS) of the motor cortex, ranging from stroke rehabilitation to cognitive enhancement. These findings raise the alternative possibility that the fine motor control of pianists may be improved by stimulating the contralateral motor cortex. 

In our interdisciplinary study, we want to use the Halo Sport neurostimulation system (a physical training aid). This is a tDCS device, designed to optimise the efficiency of training sessions and accelerate gains in any physical skill, especially when the neurostimulation is complemented by focused repetitive training. The main questions of the study are the following: do pianists experience a noticeable difference in mastering repertoire with and without the HALO Sport device, and can functional and structural changes in the brain be observed after using the Halo Sport consistently over six months? Data collection will consist of EEG tests, fMRI scans, interviews, and analysis of performances by an expert panel. The value of the research is the possibility that practising with the HALO may improve the performance of the students and that changes in the brain may be observed. Interdisciplinary engagement is essential to conduct this research. If it is possible to establish that there are functional and structural changes in the brain and improvement in the performance of the pianists, the research can be extended to other disciplines with hopefully the same positive results.

This webinar is part of a series of three webinars on Interdisciplinarity that will be presented from November to December 2020 via Microsoft Teams for a duration of 45 minutes each. The webinar topics in the series will explore the intersection between Neuroscience and Music, between Science and Entrepreneurship, and between Science and Visual Arts.  

Date: Thursday 5 November 2020
Topic: The intersection between neuroscience and music 
Time: 13:00-13:45
RSVP: Alicia Pienaar, pienaaran1@ufs.ac.za by 4 November 2020 at 12:00
Platform: Microsoft Teams

Introduction and welcome
Prof Corli Witthuhn – Vice-Rector: Research at the University of the Free State 

Presenter
Dr Frelét de Villiers

Dr de Villiers is a Senior Lecturer at the Odeion School of Music. She is head of the Methodology modules, short learning programmes, lectures in piano, music pedagogy, arts management, and is a supervisor for postgraduate students. She is a member of the Faculty of the Humanities Research Committee, Interdisciplinary Centre for Digital Futures, Scientific Committee (Arts), and the Ethics Committee (the Humanities). Her field of expertise is piano technique, with particular emphasis on the influence of the brain and the whole-brain approach to music. Her passion is the use of technology in the music teaching situation – she developed a note-learning app, PianoBoost (available on Google Play).

News Archive

Nanotechnology breakthrough at UFS
2010-08-19

 Ph.D students, Chantel Swart and Ntsoaki Leeuw


Scientists at the University of the Free State (UFS) made an important breakthrough in the use of nanotechnology in medical and biological research. The UFS team’s research has been accepted for publication by the internationally accredited Canadian Journal of Microbiology.

The UFS study dissected yeast cells exposed to over-used cooking oil by peeling microscopically thin layers off the yeast cells through the use of nanotechnology.

The yeast cells were enlarged thousands of times to study what was going on inside the cells, whilst at the same time establishing the chemical elements the cells are composed of. This was done by making microscopically small surgical incisions into the cell walls.

This groundbreaking research opens up a host of new uses for nanotechnology, as it was the first study ever in which biological cells were surgically manipulated and at the same time elemental analysis performed through nanotechnology. According to Prof. Lodewyk Kock, head of the Division Lipid Biotechnology at the UFS, the study has far reaching implications for biological and medical research.

The research was the result of collaboration between the Department of Microbial, Biochemical and Food Biotechnology, the Department of Physics (under the leadership of Prof. Hendrik Swart) and the Centre for Microscopy (under the leadership of Prof.Pieter van Wyk).

Two Ph.D. students, Chantel Swart and Ntsoaki Leeuw, overseen by professors Kock and Van Wyk, managed to successfully prepare yeast that was exposed to over-used cooking oil (used for deep frying of food) for this first ever method of nanotechnological research.

According to Prof. Kock, a single yeast cell is approximately 5 micrometres long. “A micrometre is one millionth of a metre – in laymen’s terms, even less than the diameter of a single hair – and completely invisible to the human eye.”

Through the use of nanotechnology, the chemical composition of the surface of the yeast cells could be established by making a surgical incision into the surface. The cells could be peeled off in layers of approximately three (3) nanometres at a time to establish the effect of the oil on the yeast cell’s composition. A nanometre is one thousandth of a micrometre.

Each cell was enlarged by between 40 000 and 50 000 times. This was done by using the Department of Physics’ PHI700 Scanning Auger Nanoprobe linked to a Scanning Electron Microscope and Argon-etching. Under the guidance of Prof. Swart, Mss. Swart en Leeuw could dissect the surfaces of yeast cells exposed to over-used cooking oil. 

The study noted wart like outgrowths - some only a few nanometres in diameter – on the cell surfaces. Research concluded that these outgrowths were caused by the oil. The exposure to the oil also drastically hampered the growth of the yeast cells. (See figure 1)  

Researchers worldwide have warned about the over-usage of cooking oil for deep frying of food, as it can be linked to the cause of diseases like cancer. The over-usage of cooking oil in the preparation of food is therefore strictly regulated by laws worldwide.

The UFS-research doesn’t only show that over-used cooking oil is harmful to micro-organisms like yeast, but also suggests how nanotechnology can be used in biological and medical research on, amongst others, cancer cells.

 

Figure 1. Yeast cells exposed to over-used cooking oil. Wart like protuberances/ outgrowths (WP) is clearly visible on the surfaces of the elongated yeast cells. With the use of nanotechnology, it is possible to peel off the warts – some with a diameter of only a few nanometres – in layers only a few nanometres thick. At the same time, the 3D-structure of the warts as well as its chemical composition can be established.  

Media Release
Issued by: Mangaliso Radebe
Assistant Director: Media Liaison
Tel: 051 401 2828
Cell: 078 460 3320
E-mail: radebemt@ufs.ac.za  
18 August 2010
 

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