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11 September 2020 | Story Andre Damons | Photo Francois van Vuuren (iFlair Photography)
Dr Lehlohonolo Makhakhe is from the Department of Dermatology at the University of the Free State (UFS).

A senior lecturer and specialist in the Department of Dermatology at the University of the Free State (UFS) has published the very first comprehensive African atlas on skin diseases commonly seen in the African setting. 
The African Atlas, synopsis and practical guide to clinical dermatology also contains more than 1 000 high-resolution images and is intended for medical and nursing students.

Dr Lehlohonolo Makhakhe, a full-time medical specialist (dermatologist) and the author of the book, says this is the first comprehensive full-colour atlas, with contributions from endocrinologists, haematologists, rheumatologists, psychiatrists and the UFS departments of Pharmacology, Dietetics and Paediatrics.

The project started in 2016, after Dr Makhakhe received formal approval from the UFS Ethics Committee and the provincial Department of Health and it was officially published in July 2020 by African Brilliant Minds Publishers. 

The book will have numerous benefits

Dr Makhakhe was a general practitioner with his own practice before joining the UFS to specialise. He then realised that a comprehensive manual was needed, focusing on common skin conditions in our South African setting. He further realised we lacked such a book which would be very beneficial to doctors and nurses. 

“I decided to write this book to encourage unity among doctors in different fields within medicine, particularly at the UFS, and to help promote the culture of writing and producing quality, well-researched, locally brewed content that is relevant to our setting. 
“I also wanted to play a part in providing de-commodified (affordable) books, in the hope of dispensing knowledge and promoting learning for our medical and nursing students to get sound book knowledge, so that they can better manage skin-related pathology,” added Dr Makhakhe.

He said he also aims to create revenue for the university and advance research projects through this book. It also provides an overview of the management of the conditions included in this user-friendly manual.

Challenges during the compilation of the book 

Dr Makhakhe highlighted the huge costs for the publisher, time management of the different contributors, as well as gaining the trust of the contributors for a concept that has never been done before. He aimed to change perceptions relating to dermatology as a secluded and isolated discipline, but also for the department to be seen as an integral part of the medical discipline. 

According to the author of four books (including this one), the publisher is also in talks with many nursing schools across the country to make the book available to nursing students. 

Dr Makhakhe says this atlas was by far his biggest project to date, as his first three books were short stories. He is currently working on a national project with contributors including Prof Johann Schneider (Head: Anatomical Pathology, Stellenbosch University), Prof Jacqueline Goedhals (Head: Anatomical Pathology, UFS), Prof Nndweleni Bida (Head: Anatomical Pathology, University of Pretoria), Prof Faffa Jordaan (Former head of Dermatology, Stellenbosch University) and Prof Wayne Grayson (renowned pathologist in the private sector), which will also be the first of its kind. 
“In summary, the publications are aimed at building a good name for our university through locally produced, high-quality books that are affordable. Once production costs to the publisher are settled, a sizable portion of future proceeds will then be directed to the university as per endorsement protocols.” he stated further.

Dr Makhakhe thanked the Head of the Free State Department of Health, Dr David Motau, the Rector and Vice-Chancellor of the UFS, Prof Francis Petersen, the acting Deputy Director-General of Clinical Services, Dr Marcus Molokomme, and also extended a special word of appreciation to the Head of the School of Clinical Medicine at the UFS, Prof Nathaniel Mofolo, for his assistance and support in making this project a success. He concluded by thanking all the contributors for making time for this historic project. 

The book is now fully endorsed by the UFS and will be offered as part of the curriculum for third- to final-year medical students. 

News Archive

Plant scientists address wheat rust diseases at SASPP congress
2015-02-02

Pictured from the left are: Prof Zakkie Pretorius, Dr Botma Visser and Howard Castelyn.
Photo: Supplied

In his research, Dr Botma Visser, researcher in the Department of Plant Sciences at the University of the Free State, highlighted the population dynamics of the stem rust fungus (Puccinia graminis f. sp. tritici) in Southern Africa. In recent years, two foreign stem rust races were introduced to South Africa, and a local virulence adaptation occurred in a third.

All of these races form part of the Ug99 group, a highly virulent collection of rust races endangering wheat production in many parts of the world. Despite the fact that half of the members of the Ug99 race group is prevalent in South Africa, Dr Visser’s work has clearly shown that Ug99 did not have its origin here. This emphasised the need to include neighbouring countries in the annual stem rust surveys, to proactively identify new races that could threaten local wheat production. In his research, Dr Visser also mentioned the way in which he has optimised modern molecular tools to accurately detect Ug99 isolates.

Dr Visser is one of three scientists from the Department of Plant Sciences that addressed delegates attending the biennial congress of the Southern African Society for Plant Pathology (SASPP) on the Bloemfontein Campus earlier this month on progress regarding research on wheat rust diseases conducted at the UFS.

Howard Castelyn, a PhD student in Plant Sciences, presented his research on quantifying fungal growth of the stem rust pathogen in wheat varieties displaying genetic resistance. This resistance, which is best expressed in adult plants, has the potential to remain durable in the presence of new rust variants. His presentation at the congress focused on optimising microscopic and molecular techniques to track fungal development in stem tissues of adult plants. These results now allow scientists to link rust infection levels and cellular responses with particular resistance genes expressed by the wheat plant, and contributing to the understanding and exploitation of durable resistance.

Prof Zakkie Pretorius presented his research, explaining how new genetic diversity for resistance to the stripe (yellow) rust fungus (Puccinia striiformis) is discovered, analysed and applied in South Africa. This research, conducted in collaboration with Dr Renée Prins and her team at CenGen, is unravelling the genetic basis of stripe rust resistance in a promising wheat line identified by Dr Willem Boshoff, a plant breeder at Pannar. The line and DNA markers to track the resistance genes will soon be introduced to South African wheat breeding programmes.

The rust research programme at the UFS contributes significantly to the successful control of these important crop diseases.

In addition to the contributions by the UFS, rust fungi featured prominently at the SASPP, with first reports of new diseases on sugar cane and Acacia and Eucalyptus trees in South Africa. A case study of the use of a rust fungus as a biological control agent for invasive plant species in the Western Cape, was also presented.

 

For more information or enquiries contact news@ufs.ac.za .

 

 

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