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11 September 2020 | Story Andre Damons | Photo Francois van Vuuren (iFlair Photography)
Dr Lehlohonolo Makhakhe is from the Department of Dermatology at the University of the Free State (UFS).

A senior lecturer and specialist in the Department of Dermatology at the University of the Free State (UFS) has published the very first comprehensive African atlas on skin diseases commonly seen in the African setting. 
The African Atlas, synopsis and practical guide to clinical dermatology also contains more than 1 000 high-resolution images and is intended for medical and nursing students.

Dr Lehlohonolo Makhakhe, a full-time medical specialist (dermatologist) and the author of the book, says this is the first comprehensive full-colour atlas, with contributions from endocrinologists, haematologists, rheumatologists, psychiatrists and the UFS departments of Pharmacology, Dietetics and Paediatrics.

The project started in 2016, after Dr Makhakhe received formal approval from the UFS Ethics Committee and the provincial Department of Health and it was officially published in July 2020 by African Brilliant Minds Publishers. 

The book will have numerous benefits

Dr Makhakhe was a general practitioner with his own practice before joining the UFS to specialise. He then realised that a comprehensive manual was needed, focusing on common skin conditions in our South African setting. He further realised we lacked such a book which would be very beneficial to doctors and nurses. 

“I decided to write this book to encourage unity among doctors in different fields within medicine, particularly at the UFS, and to help promote the culture of writing and producing quality, well-researched, locally brewed content that is relevant to our setting. 
“I also wanted to play a part in providing de-commodified (affordable) books, in the hope of dispensing knowledge and promoting learning for our medical and nursing students to get sound book knowledge, so that they can better manage skin-related pathology,” added Dr Makhakhe.

He said he also aims to create revenue for the university and advance research projects through this book. It also provides an overview of the management of the conditions included in this user-friendly manual.

Challenges during the compilation of the book 

Dr Makhakhe highlighted the huge costs for the publisher, time management of the different contributors, as well as gaining the trust of the contributors for a concept that has never been done before. He aimed to change perceptions relating to dermatology as a secluded and isolated discipline, but also for the department to be seen as an integral part of the medical discipline. 

According to the author of four books (including this one), the publisher is also in talks with many nursing schools across the country to make the book available to nursing students. 

Dr Makhakhe says this atlas was by far his biggest project to date, as his first three books were short stories. He is currently working on a national project with contributors including Prof Johann Schneider (Head: Anatomical Pathology, Stellenbosch University), Prof Jacqueline Goedhals (Head: Anatomical Pathology, UFS), Prof Nndweleni Bida (Head: Anatomical Pathology, University of Pretoria), Prof Faffa Jordaan (Former head of Dermatology, Stellenbosch University) and Prof Wayne Grayson (renowned pathologist in the private sector), which will also be the first of its kind. 
“In summary, the publications are aimed at building a good name for our university through locally produced, high-quality books that are affordable. Once production costs to the publisher are settled, a sizable portion of future proceeds will then be directed to the university as per endorsement protocols.” he stated further.

Dr Makhakhe thanked the Head of the Free State Department of Health, Dr David Motau, the Rector and Vice-Chancellor of the UFS, Prof Francis Petersen, the acting Deputy Director-General of Clinical Services, Dr Marcus Molokomme, and also extended a special word of appreciation to the Head of the School of Clinical Medicine at the UFS, Prof Nathaniel Mofolo, for his assistance and support in making this project a success. He concluded by thanking all the contributors for making time for this historic project. 

The book is now fully endorsed by the UFS and will be offered as part of the curriculum for third- to final-year medical students. 

News Archive

Mathematical methods used to detect and classify breast cancer masses
2016-08-10

Description: Breast lesions Tags: Breast lesions

Examples of Acho’s breast mass
segmentation identification

Breast cancer is the leading cause of female mortality in developing countries. According to the World Health Organization (WHO), the low survival rates in developing countries are mainly due to the lack of early detection and adequate diagnosis programs.

Seeing the picture more clearly

Susan Acho from the University of the Free State’s Department of Medical Physics, breast cancer research focuses on using mathematical methods to delineate and classify breast masses. Advancements in medical research have led to remarkable progress in breast cancer detection, however, according to Acho, the methods of diagnosis currently available commercially, lack a detailed finesse in accurately identifying the boundaries of breast mass lesions.

Inspiration drawn from pioneer

Drawing inspiration from the Mammography Computer Aided Diagnosis Development and Implementation (CAADI) project, which was the brainchild Prof William Rae, Head of the department of Medical Physics, Acho’s MMedSc thesis titled ‘Segmentation and Quantitative Characterisation of Breast Masses Imaged using Digital Mammography’ investigates classical segmentation algorithms, texture features and classification of breast masses in mammography. It is a rare research topic in South Africa.

 Characterisation of breast masses, involves delineating and analysing the breast mass region on a mammogram in order to determine its shape, margin and texture composition. Computer-aided diagnosis (CAD) program detects the outline of the mass lesion, and uses this information together with its texture features to determine the clinical traits of the mass. CAD programs mark suspicious areas for second look or areas on a mammogram that the radiologist might have overlooked. It can act as an independent double reader of a mammogram in institutions where there is a shortage of trained mammogram readers. 

Light at the end of the tunnel

Breast cancer is one of the most common malignancies among females in South Africa. “The challenge is being able to apply these mathematical methods in the medical field to help find solutions to specific medical problems, and that’s what I hope my research will do,” she says.

By using mathematics, physics and digital imaging to understand breast masses on mammograms, her research bridges the gap between these fields to provide algorithms which are applicable in medical image interpretation.

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