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22 April 2021 | Story Andre Damons | Photo Supplied
Dr Iqra Barakzai from the School of Pathology in the Faculty of Health Sciences is graduating on Thursday with a Doctor of Philosophy with specialisation in Virology.

The fact that South Africa is one of the countries hard stricken with an HIV/AIDS epidemic, has compelled Dr Iqra Barakzai to investigate HIV drug resistance in paediatric patients in central South Africa, so that she can have a direct impact on alleviating some of the adverse effects of this epidemic. 

Dr Barakzai, from the School of Pathology in the Faculty of Health Sciences, is graduating on Thursday (22 April 2021) with a Doctor of Philosophy with specialisation in Virology during the University of the Free State’s (UFS) fourth virtual graduation. She is currently working as a SARS-CoV-2 (COVID-19) medical scientist at the UFS/National Health Laboratory Service (NHLS) Division of Virology. 

According to Dr Barakzai, she has always had a love for research, and when she did her PhD in Medical Virology addressing some of the issues that we are currently facing with the testing of HIV/AIDS, it was like a dream come true.
“It is a great honour indeed and I still cannot believe that my journey has yielded such a humbling outcome. I am truly grateful for all the support I had, it was by God’s grace,” says Dr Barakzai. It was difficult studying during the COVID-19 pandemic, as she was not allowed on campus during her final PhD year.

Challenges studying through a pandemic 

“It was very challenging to cope due to the lockdown regulations, but I received great support from my family (parents, siblings, husband, and daughter), friends, and especially my supervisor (Prof Dominique Goedhals), whose timeless efforts, support, and enthusiasm really pushed me to achieve my goals and succeed.”

“In the beginning it was challenging to work as a medical scientist in a COVID diagnostic lab, especially due to the high volumes of COVID samples we received, which were related to the different peaks involved in the COVID pandemic, e.g., the first and second waves of COVID-19. But at the same time, it was an honour to give back to the community and serve the people during this pandemic, and I would not change it for anything,” says Dr Barakzai.

Investigated HIV drug resistance in paediatric patients

With her thesis titled, Drug resistance mutations in newly diagnosed HIV-infected infants and in children and adolescents with virological failure on ART, Dr Barakzai investigated HIV drug resistance in paediatric patients in central South Africa. The study identified increasing levels of pre-treatment drug resistance in newly diagnosed HIV-infected infants; however, protease inhibitor resistance remained rare. The findings confirmed the continued efficacy of recommended antiretroviral regimens for initiating treatment and the utility of dried blood spot samples for surveillance activities.

She decided on this study as there was an overall lack of research regarding HIV drug resistance profiles in the paediatric population in central South Africa, explains Dr Barakzai. “The aim of the study was to investigate HIV drug resistance profiles in infants born to HIV-positive mothers. Additionally, to investigate drug resistance profiles of children and adolescents who are failing antiretroviral treatment and how it negatively impacts their current and future treatment options. The findings highlighted the importance of drug resistance testing to monitor the status of HIV drug resistance in different populations across South Africa.” 

Dr Barakzai, who is inspired by the use of science to create modern technology that helps in addressing socioeconomic problems affecting South Africa, says her plan is to continue working as a COVID medical scientist and helping the community during these difficult times. However, she still has the love for research that might push her to take on a postdoctoral fellowship in the field of Virology.

She hopes to use the findings from the research study to contribute towards advancing our current knowledge of HIV drug resistance in different populations across South Africa.

News Archive

Bullying in schools: Everyone’s problem
2005-06-03

From left:  Prof Gerhardt de Klerk, Dean: Faculty of the Humanities; Prof Corene de Wet; Prof Rita Niemann, Head of the Department of Comparative Education and Educational Management in the School of Education and Prof Frederick Fourie, Rector and Vice-Chancellor of the UFS

It is not only learners who are the victums of bullying in schools, but also the teachers. Prof. Corene de Wet from the Department Comparative Education and Educational Management at the University of the Free State reported, against the background of two studies on bullying in Free State secondary schools, that bullying is a general phenomena in these schools.

Prof. de Wet, who delivered her inaugural lecture on Wednesday night, is from the Department Comparative Education and Educational Management which resorts under the School of Education at the University of the Free State. She is the first women who became a full professor the School of Education.

Prof. de Wet says, “A student is being bullied or victimized when he or she is exposed, repeatedly and over time, to negative action on the part of one or more students. Bullying always includes the intentional use of aggression, an unbalanced relationship of power between the bully and the victim, and the causing of physical pain and/or emotional misery.

In some Free State schools there are victims and perpetrators of direct and indirect verbal, as well as emotional, physical and sexual bullying.

“Adults who say that bullying are part of the growing-up process and parents who set not only academic expectations but also social expectations to their children cause that victims are unwilling to acknowledge that they are being bulled. Many parents are also unaware of the levels of bullying their children are exposed to.

“Some of the learners were at least once a month the victim of direct verbal harassment, 32,45% were assaulted by co-learners and 11,21% of them were at east once per week beat, kicked, pushed and hurt in any other physical way. Free State learners are very vulnerable to bullies at taxis and on the school yard they are mostly exposed to bullies in bathrooms.

“Learners are usually bullied by members of the same gender. However, racial composition also plays a role in some Free State schools. A grade 12 girl writes, ‘There are boys in my school who act means against black people. When the teacher is out they take a red pen and write on the projector and spray it with spirits. It looks like blood and they would say it is AIDS and my friends and I have it.’

“Educators must take note of bullying in schools and must not shrug it off as unimportant. Principals or educators could be find guilty of negligence. A large number of educator respondents, 88,29%, indicated that they would intervene in cases of verbal bullying and 89,71% would intervene if they saw learners being physically bullied. However, only 19,97% of the learners who were victims of bullying were helped by educators/ other adults from their respective schools.

“The learners’ lack of trust in their educators’ abilities and willingness to assist them in the fight against bullying has important implications for education institutions. The importance of training must be emphasised.

Learners bully their educators to undermine their confidence. In Prof. de Wet’s study on educator-targeted bullying in Free State schools 24,85% of the respondents were physically abused by their learners, 33,44% were the victims of indirect verbal bullying, and 18,1% were at one time or another sexually harassed by their learners. These learner offences may lead to suspension.

“Educators are not only victims of bullying; some of them are the bullies. The South African Council for Educators prohibits bullying by educators. It is worrying that 55,83% of the educators who participated in the research project verbally victimised learners, 50,31% physically assaulted learners and a small percentage was guilty of sexual harassment.

“Every educator and learner in South Africa has the right to life, equal protection and benefit of the law, of dignity, as well as of freedom and security of the person. These rights will only be realised in a bully-free school milieu.

“To oppose bullying a comprehensive anti-bullying programme, collective responsibility and the establishment of a caring culture at schools and in the community is necessary,” said Prof. de Wet.
 

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