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30 April 2021 | Story Dr Cindé Greyling | Photo Supplied
René and Richann as Reën.

In the same week, a lecturer at the University of the Free State graduated with a master’s degree in Political Science and topped the charts with her first single as part of the duo, Reën. Within the first week of its release, Vrystaat Vlaktes was the number one hit on iTunes, got more than 300 000 views, and the duo’s Instagram boasts more than 10 000 followers. Not bad for the shy – as she describes herself – René de Klerk. 

An interesting start 

After living in Canada for about four years, René’s family moved back to Bloemfontein where she completed the last three years of high school. She decided to return to Canada after matric for a gap year, which “turned out to be nothing like that at all!” she says. Life was much harder on her own without the protection and support of her family. “Eventually I got a job, and part of my duties were to clean the restrooms – seriously. That is where I started.” 

After applying for dozens of scholarships, René eventually got a bursary to study abroad. “I’ve always wanted to help people in some way – I really want everyone to be OK, to at least have their basic needs met.” She enrolled for a degree in International Studies, which she later completed at the UFS as a BA majoring in Political Science and Communication. Her academic potential did not go unnoticed, and she pursued further studies in Political Sciences while working and lecturing in the department.

A twist in the tale 

René met her partner, Richann Brüssow, during the reality show, Boer Soek ‘n Vrou. “Since I am shy by nature, being so exposed was unnerving, but then again, I got so much out of it.” The two hit it off as a couple, and their shared love for music soon turned into much more than either of them foresaw. “We were honestly just having fun,” René recalls, “and then a production company contacted us!” 

Initially, they thought of becoming wedding singers as a hobby, but Select Music found out about their endeavour and offered them an artist development deal. “I’m astonished,” René says, “my music background included school and university choirs. I never even considered becoming a performing artist. But then I met Richann …”

More to come

This is just the beginning of the road for René and for Reën. René will continue to leave a positive footprint wherever she goes, and Reën is soon to release their second single. “I will always be working in the field of Political Sciences and spend time in the music scene as a bonus,” she concludes. 


News Archive

Nuclear Medicine on the forefront of cancer research
2017-07-10

Description: Nuclear Medicine on the forefront of cancer research Tags: Nuclear Medicine, cancer research, Dr Je’nine Horn-Lodewyk’s, tumour detection method, cancer, Department of Nuclear Medicine 

Dr Je’nine Horn-Lodewyk’s tumour detection method
could be the cost-effective breakthrough needed to decrease
the mortality rate in breast cancer patients.
Photo: Anja Aucamp

The field of Nuclear Medicine in South Africa and the rest of the world are expanding rapidly due to the development of hybrid cameras and new radiopharmaceuticals. These developments have a huge impact on the diagnosis and therapy of cancer.

The most advanced of these cameras, Positron emission tomography combined with normal CTs (PETCT), are not yet widely available in South Africa due to the cost of the cameras and the radiopharmaceuticals. A more cost-effective alternative can be of great benefit. To achieve this, the focus should be on developing new radiopharmaceuticals that can be used with the current cost-effective gamma cameras, according to University of the Free State researcher, Dr Je’nine Horn-Lodewyk from the Department of Nuclear Medicine.

Fluorodeoxyglucose (18F-FDG), a radiolabelled glucose analogue, is currently the radiopharmaceutical most commonly used in PET/CT imaging for mainly oncology indications. Although it is considered the gold standard for imaging in several malignancies, it does have certain disadvantages. An 18F-FDG PET/CT diagnostic imaging study can cost between R25 000 and R35 000 for a single patient in the private sector. The 18F-FDG is also more radioactive, which requires much stricter handling and shielding to avoid high radiation dosages to staff and patients.

Successful research potential innovative solution
In the search for the ideal radiopharmaceutical for tumour detection, the South African National Nuclear Energy Corporation (Necsa) developed a local synthesis process for ethylenedicysteine-deoxyglucose (EC-DG). EC-DG is also a glucose analogue similar to FDG. They succeeded in labelling the compound with Technetium-99-metastable-pertechnetate (99mTcO4-), the most common nuclear medicine isotope used for approximately 95% of nuclear medicine procedures, creating 99mTc-EC-DG.

In partnership with Dr Horn-Lodewyk, this compound was successfully used in various animal models and clinical scenarios, resulting in approval by the Medicine Control Council to use it in a human study. Research is also planned in order to investigate diagnostic accuracy in other cancers like lymphoma.  The end result of this research can produce a radiopharmaceutical that is cost effective, does not require the use of costly specialised equipment, has no significant side-effects, no special patient preparation, renders late imaging possible, and has decreased radiation risks.

Dr Horn-Lodewyk is grateful for the support of her mentor, Prof Anton Otto, as well as Dr Gert Engelbrecht, Head of the Department of Nuclear Medicine, Prof Jan Rijn Zeevaart from North-West University’s Preclinical Drug Development Platform and Necsa, and Judith Wagener from Necsa. This innovative research would also not have been possible without the financial assistance of Dr Glen Taylor and Eleanor van der Westhuizen in the Directorate of Research Development.

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