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Is South Africa falling apart – where to from here?

12 August 2021 | Story Dr Nitha Ramnath

As a public higher-education institution in South Africa with a responsibility to contribute to public discourse, the University of the Free State (UFS) will be presenting the webinar as part of the Free State Literature Festival’s online initiative, VrySpraak-digitaal.

The aim of the webinar series is to discuss issues facing South Africa by engaging experts at the university and in South Africa. Some of the topics for 2021 include, among others, reimagining universities for student success; corruption; local elections, the state of business – particularly in the Free State.

In 2020, the webinar series saw the successful participation of leading experts engaging on COVID-19 and the crisis facing the country socially, economically, and politically. This year, in lieu of the Free State Arts Festival, the UFS will present the webinar virtually over a period of five months.

Fourth webinar presented on 24 August 2021
What South Africa will look like after the recent unrest in KwaZulu-Natal and Gauteng, is yet unknown. As the country is attempting to normalise while tallying the human, political, and economic cost of the riots – what we know for sure is that the events of the past few weeks have dispelled the impression of South Africa as exceptional, with a triumphant future. Moreover, the inconsistent response from government during and after the unrest laid bare the divisions within the ruling party. As South Africans are reeling from the aftermath of the looting, a lacklustre response from leaders with unreliable, conflicting messages has brought little comfort to those most in need.

What happens now? What will it take for South Africans to advance a cohesive vision to provide a sustainable future for the next generation?

Date: Tuesday, 24 August 2021
Topic: Is South Africa falling apart – where to from here?
Time: 12:30-14:00
RSVP: Alicia Pienaar, pienaaran1@ufs.ac.za by 20 August 2021

Facilitator:

Prof Francis Petersen
Rector and Vice-Chancellor, UFS

Panellists:

• Prof Bonang Mohale
UFS Chancellor
Professor of Practice
Johannesburg Business School, and
Chairman Bidvest Group Limited

• Nikiwe Bikitsha
Board Member: Nelson Mandela Foundation
CEO and co-founder: Amargi Media

• Qaanitah Hunter
Political Editor: News24

• Prof Anthony Turton
Affiliated Professor
UFS Centre for Environmental Management

Bios of speakers:

Prof Bonang Mohale

A Professor of Practice at the Johannesburg Business School’s College of Business and Economics, and Chairman of the Bidvest Group Limited, Prof Mohale is a published author and respected business leader who has held chairmanships and directorships at some of South Africa’s top companies. He currently serves on the boards of Swiss Re Africa Limited, Rand Merchant Bank Limited (RMB), the Automobile Association of South Africa, and SBV. Prof Mohale was the former Chief Executive Officer of Business Leadership South Africa (BLSA). In 2001, he received the President’s Award for his servanthood in South African industry, and in 2019 the Free Market Foundation’s Luminary Award. Prior to joining BLSA, Prof Mohale was the Chairman of Shell Downstream South Africa (Pty) Limited, and Vice-President of Shell Upstream.

Ms Nikiwe Bikitsha

Nikiwe Bikitsha is a former journalist who has been at the forefront of major national and international developments in a news and current affairs broadcasting career spanning twenty years. Nikiwe is a Fulbright Hubert H Humphrey Fellow – the Humphrey programme is a mid-career Fulbright exchange fellowship awarded to people who have demonstrated leadership. Nikiwe holds an MA in Journalism and Media Studies from the University of the Witwatersrand, and an MSc degree in African Studies from the University of Oxford. She serves as trustee on the board of the Nelson Mandela Foundation, is a member of the Deloitte Global Advisory Council and an independent non-executive director of Deloitte Africa. Despite leaving journalism, Nikiwe remains a keen observer of society.

Ms Qaanitah Hunter

Qaanitah Hunter is an award-winning political journalist and author. She is the political editor of News24 and author of Balance of Power: Ramaphosa and the future of South Africa. Qaanitah has won a number of awards for her work, including the Nat Nakasa award for brave and courageous journalism in 2019. She is currently a master’s student at the University of the Witwatersrand. She has reported fearlessly on state capture, the Zuma years, and the political transition thereafter. Her constant probing and investigations have played a pivotal role in holding truth to power. Her writing on South African politics and investigations has featured prominently on many national media platforms, often setting the agenda in the country. Qaanitah is well-versed in issues of governance and her well-rounded and balanced political reporting has contributed to her astute analysis of news and current affairs. She has fought strongly against censorship and intimidation among journalists and has been a strong advocator for the freedom of the press. Qaanitah believes that the prospect of any democracy to persevere is pinned on how free the media is and its ability to hold those in power accountable.

Prof Anthony Turton

Prof Anthony Turton is an Affiliated Professor in the Centre for Environmental Management at the University of the Free State (UFS). He specialises in strategic planning, transboundary water resource management, policy and institutional issues, conflict resolution (mitigation), political risk assessment for large infrastructural projects, and research programme design. He is also the Director of Nanodyn Systems Pty Ltd. Prof Turton’s focus is on resources, more specifically the need to overcome water and energy constraints to our future economic growth and prosperity, both as a country and the entire SADC region. As an environmentally aware person, he believes that we are reaching the limits to our current developmental approaches and will be forced to make changes in the near future, whether we like it or not. By understanding and anticipating this, Prof Turton assists organisations in staying ahead of the game by isolating fundamental drivers at work and by identifying emerging opportunities.

News Archive

Research contributes to improving quality of life for cancer patients

2016-11-21

Description: Inorganic Chemistry supervisors Tags: Inorganic Chemistry supervisors

Inorganic Chemistry supervisors in the Radiopharmacy
Laboratory during the preparation of a typical complex
mixture to see how fast it reacts. Here are, from the left,
front: Dr Marietjie Schutte-Smith, Dr Alice Brink
(both scholars from the UFS Prestige
Scholar Programme), and Dr Truidie Venter (all three
are Thuthuka-funded researchers).
Back: Prof André Roodt and Dr Johan Venter.
Photo: Supplied

Imagine that you have been diagnosed with bone cancer and only have six months to live. You are in a wheelchair because the pain in your legs is so immense that you can’t walk anymore – similar to a mechanism eating your bones from the inside.

You are lucky though, since you could be injected with a drug to control the pain so effective that you will be able to get out of the wheelchair within a day-and-a-half and be able to walk again. Real-life incidents like these provide intense job satisfaction to Prof André Roodt, Head of Inorganic Chemistry at the University of the Free State (UFS). The research, which is conducted by the Inorganic Group at the UFS, contributes greatly to the availability of pain therapy that does not involve drugs, but improves the quality of life for cancer patients.

The research conducted by the Inorganic Group under the leadership of Prof Roodt, plays a major role in the clever design of model medicines to better detect and treat cancer.

The Department of Chemistry is one of approximately 10 institutions worldwide that conducts research on chemical mechanisms to identify and control cancer. “The fact that we are able to cooperate with the Departments of Nuclear Medicine and Medical Physics at the UFS, the Animal Research Centre, and other collaborators in South Africa and abroad, but especially the methodology we utilise to conduct research (studying the chemical manner in which drugs are absorbed in cancer as well as the time involved), enhances the possibility of making a contribution to cancer research,” says Prof Roodt.

Technique to detect cancer spots on bone
According to the professor, there are various ways of detecting cancer in the body. Cancer can, inter alia, be identified by analysing blood, X-rays (external) or through an internal technique where the patient is injected with a radioactive isotope.

Prof Roodt explains: “The doctor suspects that the patient has bone cancer and injects the person with a drug consisting of an isotope (only emits X-rays and does no damage to tissue) that is connected to a phosphonate (similar to those used for osteoporosis). Once the drug is injected, the isotope (Technetium-99m) moves to the spot on the bone where the cancer is located. The gamma rays in the isotope illuminate the area and the doctor can see exactly where treatment should be applied. The Technetium-99m has the same intensity gamma rays as normal X-rays and therefore operates the same as an internal X-ray supply.” With this technique, the doctor can see where the cancer spots are within a few hours.

The same technique can be used to identify inactive parts of the brain in Alzheimer patients, as well as areas of the heart where there is no blood supply or where the heart muscle is dead.

Therapeutic irradiation of cancer
For the treatment of pain connected with cancer, the isotope Rhenium-186 is injected. Similar to the manner in which the Technetium-99m phosphonate compound is ingested into the body, the Rhenium-186 phosphonate travels to the cancer spots. Patients thus receive therapeutic irradiation – a technique known as palliative therapy, which is excellent for treating pain. A dosage of this therapy usually lasts for about two months.

The therapy is, however, patient specific. The dosages should correspond with the occurrence and size of cancer spots in the patient’s body. First, the location of the cancer will be determined by means of a technetium scan. After that, the size of the area where the cancer occurs has to be determined. The dosage for addressing total pain distribution will be calculated according to these results.

Technique to detect cancer spots on soft tissue
Another technique to detect cancer as spots on bone or in soft tissue and organs throughout the body is by utilising a different type of irradiation, a so-called PET isotope. The Fluor-18 isotope is currently used widely, and in Pretoria a machine called a cyclotron was produced by Dr Gerdus Kemp, who is a former PhD graduate from the Inorganic Research Group. The F-18 is then hidden within a glucose molecule and a patient will be injected with the drug after being tranquillised and after the metabolism has been lowered considerably. The glucose, which is the ‘food' that cancer needs to grow, will then travel directly to the cancer area and the specific area where the cancer is located will thus be traced and ‘illuminated’ by the Fluor-18, which emits its own 'X-rays'.

In the late 80s, Prof Roodt did his own postdoctoral study on this research in the US. He started collaborating with the Department of Nuclear Medicine at the UFS in the early 90s, when he initiated testing for this research.

Through their research of more than 15 years, the Inorganic Group in the Department of Chemistry has made a major contribution to cancer research. Research on mechanisms for the detection of cancer, by designing new clever chemical agents, and the chemical ways in which these agents are taken up in the body, especially contributes to the development in terms of cancer therapy and imaging, and has been used by a number of hospitals in South Africa.

The future holds great promise
Prof Roodt and his team are already working on a bilateral study between the UFS and Kenya. It involves the linking of radio isotopes, as mentioned above, to known natural products (such as rooibos tea), which possess anti-cancer qualities.

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