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24 August 2021
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Story Amanda Tongha
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In a year marked by a global pandemic, the University of the Free State (UFS) has made great strides in research, teaching, and impactful engagement.
Our 2020 journey has seen many staff members providing services to advance public knowledge of COVID-19 for the greater good of South Africa. We have produced top-rated scientists, boasting six SARChI research chairs and three A-rated scholars in our world-class workforce. Our various initiatives to ensure student success continue to bear fruit, with current and former students making their mark in the world. One such example is Qinisani Qwabe, a PhD student in the Centre for Sustainable Agriculture, Rural Development and Extension, who was selected in the education category of the Mail & Guardian Top 200 Young South Africans. He was also chosen to represent South Africa at a BRICS conference in Russia.
You can read these and other facts and figures in ‘Our 2020 Journey’ publication.
Click on image to download the document
Otorhinolaryngology research hopes to decrease morbidity
2016-10-04
Prof Riaz Seedat, Head of the
Department of
Otorhinolaryngology at the UFS
Prof Riaz Seedat, Head of the Department of Otorhinolaryngology at the UFS is a world-renowned ear, nose and throat specialist and researcher. He is also a National Research Foundation C3 rated scientist.
He is conducting his research in ear, nose and throat (ENT) pathology in a developing world setting, particularly focusing on recurrent respiratory papillomatosis and other ENT conditions. “This condition is caused by human papillomavirus (HPV), infective conditions as well as allergic rhinitis,” said Prof Seedat.
Current research is aimed at further describing the epidemiology of recurrent respiratory papillomatosis, identification of the HPV variants responsible for causing the condition and markers of disease aggressiveness.
The research has led to various international partnerships such as the multicentre collaborative studies, “Genetic Susceptibility to Papilloma-induced Voice Disturbance” at the Centre for Genomic Sciences at the Allegheny-Singer Research Institute in Pittsburgh, United States, and the HPV6/11 Global Diversity Consortium at the University of Ljubljana in Slovenia.
Although most head and neck squamous cell carcinomas are caused by excessive tobacco and alcohol use, there is an increasing body of evidence to show that HPV causes a subset of head and neck squamous cell carcinomas. However, there are few studies on the role of HPV in head and neck neoplasms in developing countries.
“Through the research we have shown that recurrent respiratory papillomatosis, caused by HPV, is not as rare in South Africa as it is in developed countries and that patients usually present respiratory papillomatosis at an advanced stage when the condition is life-threatening,” said Prof Seedat.
“It is hoped that this research will help us to address the morbidity caused by ENT conditions common in developing countries,” said Prof Seedat.