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06 August 2021 | Story Leonie Bolleurs | Photo Supplied
Prof Carlien Pohl-Albertyn, a successful scientist, is living her dream job, as she gets to pursue her passion for microbiology; a career she wanted to pursue ever since Grade 10.

Prof Carlien Pohl-Albertyn, a professor of Microbiology in the Department of Microbiology and Biochemistry, is the holder of the SARChI Chair in Pathogenic Yeasts at the University of the Free State (UFS). She is leading the Pathogenic Yeast Research Group, studying pathogenic yeast infections and necessary treatment options and bringing hope to many immunosuppressed patients battling HIV/Aids, cancer, diabetics, and other diseases. She also recently co-authored an article on the incidence of fungal infections in COVID-19 patients. 

“This is my dream job, as I get to pursue my passion for microbiology,” says Prof Pohl-Albertyn, who already knew as early as Grade 10 that she wanted to become a microbiologist. “I have always been fascinated by the natural world and have known since childhood that I would become a scientist,” she says. 

An interview with Prof Pohl-Albertyn reveals more about the persons who inspired her, her view on the development of women, and how she approaches her work. 

Is there a woman who inspires you and who you would like to celebrate this Women’s Month, and why?

“The first woman who instilled a love for the biological sciences in me was Miss Steyn, my high school Biology teacher. She had a passion for teaching that inspired me to become a microbiologist.”

Prof Pohl-Albertyn, however, states that there were many other women who constantly inspired her to be a better person. 

“My mother inspires me to take responsibility for my choices; my mother-in-law inspires me to be kinder to others; and my best friends’ mothers inspire me to persevere, even when things are difficult.”

“I am also inspired by my female friends, Ezelle van den Heever, who has shown me that there is always a plan to be made to solve a problem; Trudi O’Neill, who manages to balance high-level research, teaching, and administration with her home life; Alicia Sherriff, from whom I am learning to be more emotionally intelligent; and Janine Allen, who has expanded my horizons and regularly shows me how to look at the world in a completely different way.”

What is your response to current challenges faced by women and available platforms for women development?

“Coming from a fairly male-dominated cultural background, I realise that I have been very privileged to not experience challenges just because I am a woman. I have been able to study and work in a field that values women and men equally and have chosen a very capable and extremely supportive husband, who sees me as an equal.”

She, however, realises that this is not the case for many women, and understands that there are women who were not able to follow their dreams and make their own life choices.

Prof Pohl-Albertyn believes that any opportunity for women to overcome challenges should be encouraged, as a society will ultimately be better if everyone is able to fulfil their greatest potential.

What advice would you give to the 15-year-old you?

This successful scientist, spouse, mother of two sons, daughter, friend, and mentor to many, says that she will advise her 15-year-old self to do everything the way that she has been doing it. “I do not regret anything and would not change my life in any way,” she says. 

What would you say makes you a woman of quality, impact, and care?

“I am a person of quality because of my integrity, work ethic, and commitment to my responsibilities – something that is easy if you enjoy what you do every day.”

“I am a person of impact because of the influence I have on my colleagues, who I always treat with respect, and my students, who I teach to the best of my abilities, and which I hope will serve them well in their careers.”

“I am a person of care because I value the contributions of my colleagues and students to my own growth and development,” remarks Prof Pohl-Albertyn.

News Archive

Dr Charlotte Boucher and Lindi Heyns examine possible anti-microbial activity in the skin of Western olive toad species
2014-12-22

 

Researchers Lindi Heyns and Dr Charlotte Boucher are working together on an interdisciplinary project between the Departments of Zoology and Entomology and Veterinary Biotechnology at the University of the Free State (UFS). The focus of their research is on the preliminary biochemical description of skin secretions in some South African toads.

The project forms part of an Honours study executed by Dwayne Pike under Heyns’ supervision. He is co-supervised by Dr Boucher who is assisting with the biochemical and microbiological assays.

Dr Boucher said, “Amphibians are characterised by the presence of cutaneous glands spread over the skin. There are two types of glands, namely mucous and granular (poison), located on the inner surface of the epidermis. Mucous glands are widely dispersed over the skin, while granular glands can be grouped and enlarged in specific regions. Mucous glands are generally associated with maintenance of humidity and cutaneous respiration, whereas granular glands function in chemical defence against predators and/or microbial infection. Studies indicate that the compounds produced by the granular glands belong to numerous chemical classes with diverse pharmacological activities.”

The products secreted by granular glands are rich in low molecular weight constituents of varied molecular types, including proteins, peptides and toxins. These secretions make the toad foul-tasting to predators and even toxic to other frog species. In addition, amphibians offer an attractive source of novel antimicrobials. Studies indicate that as a response to inhabiting microorganism-rich environments they synthesise and secrete a diverse array of antimicrobial peptides (AMPs) as an innate form of defence. Extensive research by various other research groups has been carried out on antimicrobial peptides of the genus Rana; however, hardly any studies have investigated the antimicrobial activity of African frog species.

The focus of this preliminary project is to determine the protein composition of the glandular secretions of the Western olive toad (Amietophrynus poweri), using biochemical tests, such as SDS-PAGE also known as protein gel electrophoresis combined with mass-spectrometry used to identify unknown peptides and proteins. This will give us an overview of the composition of the glandular secretions. Furthermore, we are also looking at microbiological tests, which include assays that test for possible anti-microbial activity against various bacterial and fungal species.

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