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02 August 2021 | Story Leonie Bolleurs | Photo Supplied
Prof Maryke Labuschagne, a successful scientist who is doing great work to enhance food security on the African continent, admires women who have made an impact, often in male-dominated environments.

Maryke Labuschagne, Professor in Plant Breeding at the University of the Free State (UFS), is known to many for her work to enhance food security. 

She holds the National Research Foundation’s South African Research Chairs Initiative (SARChI) Chair on Disease Resistance and Quality in Field Crops, travelling all over Africa to do research on the genetic improvement of staple food crops in communities. Through decades of research and collaboration, she has also contributed to the establishment of a strong network of researchers on the continent.

During an interview in celebration of Women’s Month, Prof Labuschagne talks about her experiences as a young scientist and how she believes young female researchers should be supported and nurtured. 

Is there a woman who inspires you and who you would like to celebrate this Women’s Month, and why?

Besides the scientists she had the opportunity to work with in countries such as Zimbabwe, Zambia, Uganda, Ghana, Ethiopia, Kenya, Lesotho, Eswatini, Tunisia, and Ethiopia, she also met women who are working the fields to produce crops for their families, raising their children, and living in difficult conditions. “These women, who make it work against all odds, inspire me,” says Prof Labuschagne.

Other women she admires and who have made an impact – often in male-dominated environments – include role models from the past, such as former UK prime minister, Margaret Thatcher; physicist Marie Curie, who was far ahead of her time; and American geneticist Barbara McClintock, who won a Nobel Prize in 1983. 

What is your response to current challenges faced by women and available platforms for women development?
 
“When I started working in the Faculty of Natural and Agricultural Sciences at the UFS in 1989, it was a different world. It was a totally (white) male-dominated environment. The number of women scientists could be counted on the fingers of one hand, and they were often not given the same opportunities as their male counterparts,” she recalls.

Prof Labuschagne continues: “With women having so many opportunities today, it is now totally different.”

She believes women will always have a double burden – being responsible for a family and having to compete on an equal footing with male colleagues in the workplace. There are now, however, many platforms and support systems specifically for women, and she encourages women to make use of every available form of assistance they can get.

I would say you can have it all. Work hard, believe in yourself, follow your dreams, focus on your goals, see the opportunities – not the challenges, and leave a legacy. – Prof Maryke Labuschagne
 
What advice would you give to the 15-year-old you?

“I would say you can have it all. Work hard, believe in yourself, follow your dreams, focus on your goals, see the opportunities – not the challenges, and leave a legacy.”

She is convinced that young women can have a family and a career, even if they believe it is not possible. 
 
What would you say makes women of quality, impact, and care?
 
“I see many women at the UFS making their mark, making an impact in their chosen fields.”

According to Prof Labuschagne, what would have been unthinkable just a few decades ago, such as women serving as deans and in top management positions, is now a reality. 

“I see young female researchers boldly taking on the world, believing in themselves and their abilities, and knowing they will be successful.” She states that each of these women should be supported and nurtured, as they will have a huge influence on the course of the university’s future.

News Archive

Link between champagne bubbles and the UFS?
2012-11-16

Prof. Lodewyk Kock with an example of a front page of the publication FEMS Yeast Research, as adapted by F. Belliard, FEMS Central Office.
Photo: Leatitia Pienaar
15 November 2012

What is the link between the bubbles in champagne and breakthrough research being done at the Mayo Clinic in America? Nano research being done at our university.

Prof. Lodewyk Kock of Biotechnology says a human being consists of millions of minute cells that are invisible to the eye. The nano technology team at the UFS have developed a technique that allows researchers to look into such a cell, as well as other microorganisms. In this way, they can get an idea of what the cell’s “insides” look like.

The UFS team – consisting of Profs. Kock, Hendrik Swart (Physics), Pieter van Wyk (Centre for Microscopy), as well as Dr Chantel Swart (Biotechnology), Dr Carlien Pohl (Biotechnology) and Liza Coetsee (Physics) – were amazed to see that the inside of cells consist of a maze of small tunnels or blisters. Each tunnel is about 100 and more nanometres in diameter – about one ten thousandth of a millimetre – that weaves through the cells in a maze.

It was also found that these tunnels are the “lungs” of the cells. Academics doing research on yeast have had to sit up and take notice of the research being done at the UFS – to the extent that these “lungs” will appear on the front page of the highly acclaimed FEMS Yeast Research for all of 2013.

The Mayo Clinic, in particular, now wants to work with the UFS to study cancer cells in more detail in order to fight this disease, says Prof. Kock. The National Cancer Institute of America has also shown interest. This new nano technology for biology can assist in the study and development of nano medicine that can be used in the treatment of cancer and other life threatening diseases. Nano medicine uses nano metal participles that are up to one billionth of a metre in size.

Prof. Kock says laboratory tests indicate that nano medicine can improve the efficacy of anti-cancer medicine, which makes the treatment less toxic. “According to the Mayo Clinic team, nano particles are considered as a gold cartridge which is being fired directly at a cancer tumour. This is compared to fine shot that spreads through the body and also attacks healthy cells.”

“This accuracy implies that the chemotherapy dose can be lowered with fewer side effects. The Mayo Clinic found that one-tenth of the normal dosage is more effective against pancreas cancer in this way than the full dosage with a linkage to nano particles. According to the clinic, this nano medicine could also delay the spread of cancer,” says Prof. Kock.

The nano particles are used as messengers that convey anti-cancer treatment to cancer cells, where it then selectively kills the cancer cells. The transport and transfer of these medicines with regard to gold nano particles can be traced with the UFS’s nano technology to collect more information, especially where it works on the cell.

“With the new nano technology of the UFS, it is possible to do nano surgery on the cells by slicing the cells in nanometre thin slices while the working of the nano medicine is studied. In this way, it can be established if the nano medicine penetrates the cells or if it is only associated with the tiny tunnels,” says Prof. Kock.

And in champagne the small “lungs” are responsible for the bubbles. The same applies to beer and with this discovery a whole new reach field opens for scientists.

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