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08 December 2021 | Story Michelle Nothling | Photo Supplied
Lentsu Nchabeleng
Dr Ntheno Nchabeleng was appointed as the Deputy Director in the Gender and Anti-Discrimination Office within the Unit for Institutional Change and Social Justice.

A total of 10 006 rape cases were reported between April and June 2021. This is according to the latest SA crime statistics for the first quarter of 2021/2022. From a sample of 5 439 of these rape cases, 3 766 of incidents took place in the victim’s home or that of the rapist. A shadow pandemic of gender-based violence against our women and children is raging in South Africa.

It is within this global and local context that the Gender and Anti-Discrimination Office (GEADO) at the university is making inroads into supporting survivors of gender-based violence (GBV) and changing gender stereotypes.

GEADO in focus

GEADO is situated within the Unit for Institutional Change and Social Justice on the Bloemfontein Campus. It is mandated to deal with incidents of unfair discrimination and GBV as it relates to the UFS community, and to conduct advocacy and training in these areas. Deputy Director of GEADO, Dr Ntheno Nchabeleng, explains that “through high-impact practices and interventions, the Office works to systematically reduce case attrition to ensure that all reports and cases follow procedurally just processes”.

GEADO has been established at all the UFS campuses with well-trained and fully equipped Senior Gender Officers leading each. Geraldine Langau—supported by research assistant Delisile Mngadi—is managing the office at the Bloemfontein Campus, Chelepe Mocwana the Qwaqwa Campus, and Sivuyisiwe Magayana oversees the South Campus office.

Addressing gender-based violence

Prevention and response to GBV are at the core of GEADO’s work. With our country wracked by sexual violence and femicide, “it has become a nightmare to be a woman in South Africa”, Dr Nchabeleng says.

Its preventative efforts focus on the underlying causes of GBV to transform patriarchal notions, misogynistic norms, power imbalances, and toxic gender stereotypes. Fostering collaboration with various strategic partners to strengthen its impact, GEADO recently started working with Amnesty International Sub-Saharan Africa and Amnesty International Latin America to spread awareness on various forms of violence experienced by vulnerable populations. GEADO has also partnered with other local stakeholders in an effort to eradicate GBV through programming that includes awareness campaigns, online mobilisation, training, and webinars.

Becoming part of the solution

“Become change agents,” Dr Nchabeleng urges. One way to start shifting attitudes and mindsets is to change the way we speak. Examples would be to refrain from sexist and discriminatory language and phrases that undermine and degrade our women. Gendered name-calling generally depicts women and girls as inferior and less than fully human. Another area of concern is the way young people — especially young men — engage in disparaging conversations about women on social media platforms. This behaviour needs to cease. As a society, we also need to stop victim blaming, stop normalising rape culture, and stop entertaining sexual violence jokes,” Dr Nchabeleng says.

These changes start with each of us.

Incidents of GBV and discrimination can be reported to GEADO at:
Bloemfontein Campus: +27 51 401 3982
South Campus: +27 51 401 7544
Qwaqwa Campus: +27 58 718 5431

Sexual Assault Response Team (SART):
www.ufs.ac.za/sart 
Toll-free number +27 80 020 4682

News Archive

UFS study on cell development in top international science journal
2008-09-16

A study from the University of the Free State (UFS) on how the change in the packaging of DNA with cell development influenced the expression of genes, will be published in this week’s early edition of the prestigious international, peer-reviewed science journal, the Proceeding of the National Academy of Sciences of the USA (PNAS).

The PNAS journal has an impact factor of 10, which means that studies published in the journal are, on average, referred to by ten other scientific studies in a two year period. The South African Journal of Science, by comparison, has an impact factor of 0.7.

The UFS study, funded by the Wellcome Trust and the National Research Foundation (NRF), looked at how the change in the packaging of DNA with cell development influenced the expression of genes. It is very relevant to research on stem cells, an area of medicine that studies the possible use of undifferentiated cells to replace damaged tissue.

Prof. Hugh Patterton, of the Department of Microbial, Biochemical and Food Biotechnology at the UFS, who led the study, said: "We are extremely proud of this study. It was conceived in South Africa, it was performed in South Africa, the data were analysed in South Africa, and it was published from South Africa."

When a gene is expressed, the information encoded in the gene is used to manufacture a specific protein. In eukaryotes, which include humans, there is approximately 1m of DNA, containing the genes, in every cell. This length of DNA has to fit into a cell nucleus with a diameter of only about 10 micrometer. In order to fit the DNA into such a small volume, eukaryotic cells wrap their DNA onto successive protein balls, termed nucleosomes. Strings of nucleosomes, resembling a bead of pearls, is folded into a helix to form a chromatin fiber. The study from the UFS investigated how the binding of a specific protein, termed a linker histone, that binds to the length of DNA between nucleosomes, influenced the formation of the chromatin fiber and also the activity of genes.

"We found that the linker histone bound to chromatin in yeast, which we use as a model eukaryote, under conditions where virtually all the genes in the organism were inactive. It was widely believed that the binding of the linker histone caused the inactivation of genes. We studied the relationship between the amount of linker histone bound in the vicinity of each gene and the expression of that gene for all the genes in yeast, using genomic techniques. We made the surprising discovery that even through the linker histone preferentially bound to genes under conditions where the genes were shut off, this inactivation of genes was not caused by the binding of the linker histone and folding of the chromatin,” said Prof. Patterton.

He said: “Instead our data strongly suggested that the observed anti-correlation was due to the movement of enzymes along the DNA molecule, involved in processing the information in genes for the eventual manufacture of proteins. This movement of enzymes displaced the linker histones from the DNA. This finding now requires a rethink on aspects of how packaging of DNA influences gene activity."

Prof. Patterton said that his research group, using the Facility for Genomics and Proteomics as well as the Bioinformatics Node at the UFS, was currently busy with follow-up studies to understand how other proteins in nucleosomes affected the activities of genes, as well as with projects to understand how chemicals found in red wine and in green tea extended lifespan. "We are certainly having a marvelous time trying to understand the fundamental mechanisms of life, and the UFS is an exciting place to be if one was interested in studying life at the level of molecules," he said.


Media Release
Issued by: Lacea Loader
Assistant Director: Media Liaison
Tel: 051 401 2584
Cell: 083 645 2454
E-mail: loaderl.stg@ufs.ac.za  
18 September 2008
 

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