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08 February 2021 | Story André Damons | Photo Charl Devenish
Prof Mamello Sekhoacha, Associate Professor from the Department of Pharmacology in the Faculty of Health Sciences, was appointed by Dr Zweli Mkhize, Minister of Health, as the new chairperson of the National Health Research Ethics Council of South Africa (NHREC).

A researcher in the field of drug discovery and development at the University of the Free State (UFS) has been appointed by Dr Zweli Mkhize, Minister of Health, as the new chairperson of the National Health Research Ethics Council of South Africa (NHREC).

Prof Mamello Sekhoacha, Associate Professor from the Department of Pharmacology in the Faculty of Health Sciences, was appointed as a member of the NHREC council in 2013, and later became the chairperson of the NHREC’s Norms and Standards Committee responsible for developing and revising guidelines for health research. Prof Sekhoacha was appointed deputy chairperson of the council in 2018 and has played an integral part in setting ethical standards for conducting health research in the country.

 Responsibilities of the NHREC

The NHREC is the national statutory body responsible for the governance and advancement of health research ethics in South Africa. Some of the responsibilities of the council are to set ethical norms and standards for health research by developing and revising the guidelines pertaining to health research; to promote and monitor compliance with existing regulations by health research ethics committees; and to build capacity in research ethics committees through robust registration and audit processes.

These responsibilities of the NHREC rest on the need to ensure ethical integrity in research involving human participants and animal subjects, and that research is based on sound scientific and ethical principles.

“It is an honour for me to serve on the NHREC for the third term. The NHREC has achieved remarkable outputs over the past three years, and I believe, given the current composition of the council members, this momentum will not be lost. One of the goals of the NHREC is to further broaden the scope of the ethics in health research guidelines from ‘biomedical research’ to ‘health-related research’ to ensure that adequate guidance is provided for those in health-related disciplines, as a response to the changing environment of research involving humans and the broader meaning of health research.” 

“We need more comprehensive guidelines with nuanced commentaries to indicate how the ethical principles that emanated from biomedical research involving humans, could be effectively implemented in other disciplines of health-related research,” says Prof Sekhoacha. 

Global paradigm shift in role and integration of ethics in health research

Having been a council member since 2013, Prof Sekhoacha, whose training spans from pre-clinical laboratory experimentation, the use of animals in research, clinical trials, and working with indigenous communities, says there is a global paradigm shift in the role and integration of ethics in health research in almost all aspects of research, with an increased emphasis on the scientific and social value of research: the prospect of generating the knowledge in a manner that protects and promotes people's health. Considerations of the NHREC go beyond developing ethical guidelines or ensuring the efficient functioning of the ethics committees, to raising awareness among research institutions and researchers to continually promote ethically sound research conduct. 

The subject of ethics in health research is pivotal and reflective of the values of both the institution and the country at large. 

UFS uses Prof Sekhoacha’s expertise on ethics

Prof Sekhoacha is also a co-opted advisory member in the Senate Research Ethics Committee of the UFS and facilitates workshops and seminars on research ethics offered by the Postgraduate School.

Prof Corli Witthuhn, Vice-Rector: Research and Internationalisation, says it is a great honour for the UFS that Prof Sekhoacha has been elected chair of the NHREC.  “The NHREC governs the research ethics processes in South Africa, and it is strategically important for the UFS to now have one of our own academics play such a nationally important role.  We have been using Prof Sekhoacha’s expertise on issues of ethics and we are looking forward to working with her to continue to better our own ethics processes.”

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New Genetics building on Bloemfontein Campus spirals into new frontiers
2015-09-11

On Thursday 3 September 2015, the Department of Genetics hosted the official opening of its new offices on the Bloemfontein Campus of the University of the Free State (UFS).

Prof Jonathan Jansen, Vice-Chancellor and Rector of the UFS, Prof Neil Heideman, Dean of the Faculty of Natural and Agricultural Sciences, and Prof Paul Grobler, Head of the Department of Genetics cut the ribbon, symbolising the opening of this building with its state-of-the-art facilities.

The new genetics building boasts a new administration block with a reception area, seven offices, a small committee room, and a seminar room for 50 people. Furthermore, the undergraduate laboratory block provides a laboratory for 150 students. The research block has facilities for 30 researchers.

This building also hosts a chemical waste sorting and storage facility. This is a first for the university.

Several sites were investigated for the new building, but due to its size and envisaged second phase, a “green fields” site was found on the western side of the campus. The main entrance caters for visitors from the north, students on foot, and those using the parking area in front of the library. The secondary south entrance is for those who use the dedicated parking area south of the building. The link between these two entrances is the spine of the building, a helix with services/buildings spaced on either side. The helix will be extended in the second phase to keep the circulation and linkage of buildings as simple as possible.

In his opening speech, Prof Grobler gave a breakdown of the history of the Department of Genetics. Today, this department, which opened its doors at the UFS in 1960, is proud of its 131 students and 46 honours students.

According to Major-General Edward Ngokha, Head of the Forensic Science Laboratory, students who graduate from the UFS in the field of genetics make excellent employees. The Forensic Science Laboratory has employed 25 honours students since the BSc Honours degree in Genetics was implemented in 2010.

“The UFS delivers education of high quality and high standards. Thank you for your contribution toward fighting crime by delivering well-prepared, committed employees,” said Major-General Ngokha.

The department presents programmes on population conservation genetics, plant molecular genetics, cytogenetics, forensic genetics, forensic science, human genetics, and behavioural genetics.

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