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08 February 2021 | Story André Damons | Photo Charl Devenish
Prof Mamello Sekhoacha, Associate Professor from the Department of Pharmacology in the Faculty of Health Sciences, was appointed by Dr Zweli Mkhize, Minister of Health, as the new chairperson of the National Health Research Ethics Council of South Africa (NHREC).

A researcher in the field of drug discovery and development at the University of the Free State (UFS) has been appointed by Dr Zweli Mkhize, Minister of Health, as the new chairperson of the National Health Research Ethics Council of South Africa (NHREC).

Prof Mamello Sekhoacha, Associate Professor from the Department of Pharmacology in the Faculty of Health Sciences, was appointed as a member of the NHREC council in 2013, and later became the chairperson of the NHREC’s Norms and Standards Committee responsible for developing and revising guidelines for health research. Prof Sekhoacha was appointed deputy chairperson of the council in 2018 and has played an integral part in setting ethical standards for conducting health research in the country.

 Responsibilities of the NHREC

The NHREC is the national statutory body responsible for the governance and advancement of health research ethics in South Africa. Some of the responsibilities of the council are to set ethical norms and standards for health research by developing and revising the guidelines pertaining to health research; to promote and monitor compliance with existing regulations by health research ethics committees; and to build capacity in research ethics committees through robust registration and audit processes.

These responsibilities of the NHREC rest on the need to ensure ethical integrity in research involving human participants and animal subjects, and that research is based on sound scientific and ethical principles.

“It is an honour for me to serve on the NHREC for the third term. The NHREC has achieved remarkable outputs over the past three years, and I believe, given the current composition of the council members, this momentum will not be lost. One of the goals of the NHREC is to further broaden the scope of the ethics in health research guidelines from ‘biomedical research’ to ‘health-related research’ to ensure that adequate guidance is provided for those in health-related disciplines, as a response to the changing environment of research involving humans and the broader meaning of health research.” 

“We need more comprehensive guidelines with nuanced commentaries to indicate how the ethical principles that emanated from biomedical research involving humans, could be effectively implemented in other disciplines of health-related research,” says Prof Sekhoacha. 

Global paradigm shift in role and integration of ethics in health research

Having been a council member since 2013, Prof Sekhoacha, whose training spans from pre-clinical laboratory experimentation, the use of animals in research, clinical trials, and working with indigenous communities, says there is a global paradigm shift in the role and integration of ethics in health research in almost all aspects of research, with an increased emphasis on the scientific and social value of research: the prospect of generating the knowledge in a manner that protects and promotes people's health. Considerations of the NHREC go beyond developing ethical guidelines or ensuring the efficient functioning of the ethics committees, to raising awareness among research institutions and researchers to continually promote ethically sound research conduct. 

The subject of ethics in health research is pivotal and reflective of the values of both the institution and the country at large. 

UFS uses Prof Sekhoacha’s expertise on ethics

Prof Sekhoacha is also a co-opted advisory member in the Senate Research Ethics Committee of the UFS and facilitates workshops and seminars on research ethics offered by the Postgraduate School.

Prof Corli Witthuhn, Vice-Rector: Research and Internationalisation, says it is a great honour for the UFS that Prof Sekhoacha has been elected chair of the NHREC.  “The NHREC governs the research ethics processes in South Africa, and it is strategically important for the UFS to now have one of our own academics play such a nationally important role.  We have been using Prof Sekhoacha’s expertise on issues of ethics and we are looking forward to working with her to continue to better our own ethics processes.”

News Archive

UFS Cardiovascular Research Centre a South African solution to continental crisis
2015-11-30

From left are: Dr Robert Kleinloog, president of the Society of Cardiothoracic Surgeons of South Africa, Prof Jonathan Jansen, Vice-Chancellor and Rector of the University of the Free State (UFS), Prof Robert Frater after which the Robert W M Frater Cardiovascular Research Centre was named and Prof Francis Smit, head of Cardiothoracic Surgery at the UFS, at the launch of the new centre.
Photo: Johan Roux

“You don’t have to be in New York or any big city in the world to establish a cardiovascular centre that delivers work of world standards. I’ve learned that extraordinary things are achieved by ordinary people who apply themselves accordingly. This research centre is a South African solution to a continental challenge”.

These were the words of Prof Robert Frater at the opening of the new Robert W M Frater Cardiovascular Research Centre in the Department of Cardiothoracic Surgery at the University of the Free State (UFS) School of Medicine.

The centre, one of only two of the kind in the country, will focus on bioengineering and cardiovascular research. It was opened on Wednesday 18 November 2015 in the Francois Retief Building on the Bloemfontein campus.

The centre is named after Prof Robert W.M Frater in recognition of his vast contribution to the UFS. He is internationally recognised for his outstanding academic, clinical, and scientific contributions to cardiac surgery. Prof Frater has also been actively involved in research activities of the Department of Cardiothoracic Surgery for the last 10 years. In 2011, he received an honorary doctorate from the UFS.

Under the leadership of Prof Francis Smit, head of Cardiothoracic Surgery, the department has been described as a dynamic unit at the forefront of meeting the different changes in Southern Africa while maintaining an excellent clinical and academic track record.

At the opening, Prof Jonathan Jansen, Vice-Chancellor and Rector of the UFS, thanked Prof Frater for his presence at, involvement in, and support of the UFS. “I am looking forward to working in collaboration with the department to make this university a research centre of excellence in the continent”, he said.

The centre has existing endeavours already in operation, including Population projects, Clinical studies, and Clinical pathology, to name three. In collaboration with the Central University of Technology, the University of Stellenbosch, and Charite University of Berlin, among numerous others, the centre will be an appropriate help to an African challenge.

Its introduction promises advanced research outcomes with the potential to make the Department of Cardiothoracic Surgery a world-class competitor.

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