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04 January 2021 | Story Igno van Niekerk | Photo Francois van Vuuren (iFlair)
Anton Roodt

 The Afrikaans words, weerlose meganika, can be roughly translated as ‘vulnerable mechanics’. If you do not know the exact meaning of this, rest assured, you are not alone. At least one person does. Anton Roodt of Roodt Architects has been summoning a storm of positive reviews in the literary world with his debut offering, which is neither an environmentally friendly building nor creative historical restoration for which he is renowned, but a book.

Weerlose meganika was written as part of the requirements for Roodt’s fourth MA degree – all obtained at the University of the Free State (UFS), where the Roodts have been part of the UFS family for three generations. Anton’s father was the Head of the department of Architecture, and his son recently completed his studies in the same department. His wife, Zarine, has been involved as lecturer and research fellow in the Department of Communication Science. Roodt’s wide spectrum of interests shows in the variety of his MA degrees (Architecture, Town and Regional Planning, Environmental Management, and now – Creative Writing).

Roodt, renowned for his creativity and innovative manner of working, has barely stepped into the world of literature; yet the book, published by Tafelberg Publishers, is being described in words probably never used by critics: “verrassend vernuwend” (surprisingly refreshing), “baldadig,” (which I can only translate as ‘wildly playful’), and nostalgic science fiction.

In a Zoom conversation, Roodt shared that he wrote mostly in his spare time. Many hours of study in the buzz of architecture classrooms taught him to focus anywhere and anytime. According to Roodt, the chapters that had to be removed in the final edits of Weerlose meganika comprise sufficient material for a second book. 

Anton and his son, Leon-Pierre, both worked on the cover of Weerlose meganika: Anton designed it and Leon-Pierre was responsible for the graphics. Although publishers usually prefer to appoint their own designers, Tafelberg liked and kept the design as presented. This was no surprise, as design is not new to Anton who, as a student, was involved in the design of rag posters. During a particular rag, he realised that the poster design was extremely successful, as about 90% of them were stolen by students from lampposts and other areas. 

Roodt’s recipe for success? He is naturally curious and wants to learn more about many things. This allows him to connect with interesting people such as his fellow students and lecturers (Dr Francois Smith and Prof Henning Pieterse) in the Creative Writing course, where they kept on pushing each other to improve their work. It is clear that Roodt is on a lifelong journey of learning. And, in case you are wondering – yes, he recently started his PhD studies. At the UFS, of course.

When I asked Anton about the strange title, Weerlose meganika, he explained that he has always been fascinated by juxtapositions. He loves bringing seemingly unrelated elements together. 

Looking at the reviews, he has been successful once again. 

*** If you are curious to know more, Weerlose meganika is available at most bookstores, as well as online.

News Archive

Collaboration between UFS and Mayo Clinic to revolutionise cancer treatment
2014-06-27



Attending the lecture were, from the left: Dr Chantel Swart, Prof Lodewyk Kock, Prof Debabrata Mukhopadhyay, Prof James du Preez; back: Prof Pieter van Wyk.
Dr Swart, Profs Kock and Du Preez are from the Department of Microbial, Biochemical and Food Biotechnology. Prof Mukhopadhyay is from the Mayo Clinic (US) and Prof Van Wyk is from the Centre for Microscopy at the UFS.
Photo: Supplied
The UFS made a discovery that may have enormous implications for the treatment of diseases in humans.

Since the discovery, the UFS joined forces with the Mayo Clinic in Rochester, US, in the fight against cancer.

In this collective effort, UFS researchers would be able to assist the Mayo team to:
• see how treatment in cancer patients is progressing,
• target treatments more effectively,
• reduce dosages in order to make treatment gentler on the patient,
• track the effectiveness of the chemotherapy drugs used, and
• gain an accurate view of how the cancer is being eliminated.

Prof Lodewyk Kock, Outstanding Professor at the Department of Microbial, Biochemical and Food Biotechnology, and his team incidentally created a technique to use argon gas particles for the first time on biological material to slice open cells to look inside.

The team that supported Prof Kock includes Dr Chantel Swart, Khumisho Dithebe (PhD student), Prof Hendrik Swart (Department of Physics) and Prof Pieter van Wyk (Centre for Microscopy).

Prof Debabrata Mukhopadhyay from the Mayo Clinic in Rochester, US, got to hear about this breakthrough at the UFS and a collaboration between the two institutions was established.

During a visit to the Bloemfontein Campus, Prof Mukhopadhyay explained novel techniques that make use of gold nanoparticles. These particles attach to chemotherapeutic drugs to selectively target cancer cells – dramatically decreasing the side effects to normal human cells.

For these new drugs (coupled to gold nanoparticles) to be accepted into clinical practice, visual and chemical proof is needed, though. This is where the technique developed by the UFS will play a vital role.

With the technique to look inside cells, the composition, location and metabolism of these drugs can be determined. This will aid in a proof of concept for the application of the nano-drugs. Furthermore, it will enable approval for use of these drugs in clinical trials and eventually could revolutionise cancer treatment as a whole.

For video lectures on the technique used, as well as its findings, follow these links:

1. http://vimeo.com/63643628 (Comic version for school kids)

2. http://vimeo.com/61521401 (Detailed version for fellow scientists)

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