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08 January 2021 | Story Charlene Stanley | Photo Charlene Stanley
Dr Matteo Grilli with his first book in front of the North Block on the Bloemfontein Campus.
Dr Matteo Grilli from the International Studies Group (ISG) became the second ISG scholar in just four years to receive a coveted P-rating from the NRF.

A P-rating (Prestigious Awards) by the National Research Foundation (NRF) is the holy grail for all young researchers at all South African universities and across all disciplines. It is a valuable tool for benchmarking local researchers against the best in the world. But it is hard to come by. Only one or two researchers are normally granted this sought-after standing each year. 

Dr Matteo Grilli, a young Italian historian from the International Studies Group (ISG), says he was “pleasantly surprised” when he recently got the nod from the NRF, attributing his P-rating to the “excellent training and support” that he received from the UFS, and specifically the ISG and its head, Prof Ian Phimister.  

Unique achievement for ISG
What makes this achievement even more significant, is that the ISG produced another P-rated scholar a mere four years ago (Dr Daniel Spence in 2016).

“For Prof Phimister to produce two P-rated researchers in such a short time is really an unbelievable achievement. I am not aware of any other department at any South African university that could achieve this,” says Dr Glen Taylor, Senior Director: Research Development. 

P-rating requirements
The NRF’s P category honours young researchers (normally younger than 35 years) who have held a doctorate or equivalent qualification for less than five years. Researchers in this group are recognised by all or the vast majority of reviewers as having demonstrated the potential to become future international leaders in their field based on exceptional research performance and output from their doctoral and/or early postdoctoral research careers.

UFS becoming a mecca for African studies
Dr Grilli produced his first book, Nkrumaism and African Nationalism: Ghana's Pan-African Foreign Policy in the Age of Decolonisation around two years ago, after being accepted as a postdoc scholar by the ISG in 2015.

This unique research centre was established towards the end of 2012, with the aim of attracting and recruiting high-calibre postgraduate students and postdoctoral fellows from all over the world to the UFS. 

“Working at the ISG has undoubtedly been the best experience of my life and made me the solid scholar I am today. At the ISG, I found the best working environment you could possibly have in an academic setting, even compared to the Northern Hemisphere,” Dr Grilli says.

He believes the centre’s strength lies in the “exceptional exchange” that researchers have with their peers, allowing them to not only master their research subject but also to learn from other members’ research and methodologies.

“In my view, the ISG is concretely contributing to bringing the centre of African studies back to the African continent,” he enthuses.

Passion for Southern African politics
Dr Grilli specialises in the political history of Ghana and Southern Africa, focusing on transnational histories of African liberation movements, the history of Pan-Africanism, the Cold War and decolonisation in Africa, and the history of European migrations in sub-Saharan Africa (particularly Italian communities in Ghana and the Congo DRC). 

He is currently working on a book project about the history of Pan-Africanism, Socialism, and Nationalism in Southern Africa, particularly in Lesotho, eSwatini, and Botswana.

Asked what advice he had for young researchers, he echoes the counsel he received from Prof Phimister at the start of his tenure at the ISG: 

“Always aim high. Don’t be intimidated by the fact that there is a lot of competition in the academia, nor that you might be disadvantaged because you work in the Global South. If you work hard, your research will speak for itself and you will be able to publish solid works even in the most prestigious journals of the Northern Hemisphere.”

News Archive

Nanotechnology breakthrough at UFS
2010-08-19

 Ph.D students, Chantel Swart and Ntsoaki Leeuw


Scientists at the University of the Free State (UFS) made an important breakthrough in the use of nanotechnology in medical and biological research. The UFS team’s research has been accepted for publication by the internationally accredited Canadian Journal of Microbiology.

The UFS study dissected yeast cells exposed to over-used cooking oil by peeling microscopically thin layers off the yeast cells through the use of nanotechnology.

The yeast cells were enlarged thousands of times to study what was going on inside the cells, whilst at the same time establishing the chemical elements the cells are composed of. This was done by making microscopically small surgical incisions into the cell walls.

This groundbreaking research opens up a host of new uses for nanotechnology, as it was the first study ever in which biological cells were surgically manipulated and at the same time elemental analysis performed through nanotechnology. According to Prof. Lodewyk Kock, head of the Division Lipid Biotechnology at the UFS, the study has far reaching implications for biological and medical research.

The research was the result of collaboration between the Department of Microbial, Biochemical and Food Biotechnology, the Department of Physics (under the leadership of Prof. Hendrik Swart) and the Centre for Microscopy (under the leadership of Prof.Pieter van Wyk).

Two Ph.D. students, Chantel Swart and Ntsoaki Leeuw, overseen by professors Kock and Van Wyk, managed to successfully prepare yeast that was exposed to over-used cooking oil (used for deep frying of food) for this first ever method of nanotechnological research.

According to Prof. Kock, a single yeast cell is approximately 5 micrometres long. “A micrometre is one millionth of a metre – in laymen’s terms, even less than the diameter of a single hair – and completely invisible to the human eye.”

Through the use of nanotechnology, the chemical composition of the surface of the yeast cells could be established by making a surgical incision into the surface. The cells could be peeled off in layers of approximately three (3) nanometres at a time to establish the effect of the oil on the yeast cell’s composition. A nanometre is one thousandth of a micrometre.

Each cell was enlarged by between 40 000 and 50 000 times. This was done by using the Department of Physics’ PHI700 Scanning Auger Nanoprobe linked to a Scanning Electron Microscope and Argon-etching. Under the guidance of Prof. Swart, Mss. Swart en Leeuw could dissect the surfaces of yeast cells exposed to over-used cooking oil. 

The study noted wart like outgrowths - some only a few nanometres in diameter – on the cell surfaces. Research concluded that these outgrowths were caused by the oil. The exposure to the oil also drastically hampered the growth of the yeast cells. (See figure 1)  

Researchers worldwide have warned about the over-usage of cooking oil for deep frying of food, as it can be linked to the cause of diseases like cancer. The over-usage of cooking oil in the preparation of food is therefore strictly regulated by laws worldwide.

The UFS-research doesn’t only show that over-used cooking oil is harmful to micro-organisms like yeast, but also suggests how nanotechnology can be used in biological and medical research on, amongst others, cancer cells.

 

Figure 1. Yeast cells exposed to over-used cooking oil. Wart like protuberances/ outgrowths (WP) is clearly visible on the surfaces of the elongated yeast cells. With the use of nanotechnology, it is possible to peel off the warts – some with a diameter of only a few nanometres – in layers only a few nanometres thick. At the same time, the 3D-structure of the warts as well as its chemical composition can be established.  

Media Release
Issued by: Mangaliso Radebe
Assistant Director: Media Liaison
Tel: 051 401 2828
Cell: 078 460 3320
E-mail: radebemt@ufs.ac.za  
18 August 2010
 

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