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Dr Matteo Grilli achieves top NRF rating

08 January 2021 | Story Charlene Stanley | Photo Charlene Stanley

Dr Matteo Grilli with his first book in front of the North Block on the Bloemfontein Campus. — Dr Matteo Grilli from the International Studies Group (ISG) became the second ISG scholar in just four years to receive a coveted P-rating from the NRF.

A P-rating (Prestigious Awards) by the National Research Foundation (NRF) is the holy grail for all young researchers at all South African universities and across all disciplines. It is a valuable tool for benchmarking local researchers against the best in the world. But it is hard to come by. Only one or two researchers are normally granted this sought-after standing each year.

Dr Matteo Grilli, a young Italian historian from the International Studies Group (ISG), says he was “pleasantly surprised” when he recently got the nod from the NRF, attributing his P-rating to the “excellent training and support” that he received from the UFS, and specifically the ISG and its head, Prof Ian Phimister.

Unique achievement for ISG

What makes this achievement even more significant, is that the ISG produced another P-rated scholar a mere four years ago (Dr Daniel Spence in 2016).

“For Prof Phimister to produce two P-rated researchers in such a short time is really an unbelievable achievement. I am not aware of any other department at any South African university that could achieve this,” says Dr Glen Taylor, Senior Director: Research Development.

P-rating requirements

The NRF’s P category honours young researchers (normally younger than 35 years) who have held a doctorate or equivalent qualification for less than five years. Researchers in this group are recognised by all or the vast majority of reviewers as having demonstrated the potential to become future international leaders in their field based on exceptional research performance and output from their doctoral and/or early postdoctoral research careers.

UFS becoming a mecca for African studies

Dr Grilli produced his first book, Nkrumaism and African Nationalism: Ghana's Pan-African Foreign Policy in the Age of Decolonisation around two years ago, after being accepted as a postdoc scholar by the ISG in 2015.

This unique research centre was established towards the end of 2012, with the aim of attracting and recruiting high-calibre postgraduate students and postdoctoral fellows from all over the world to the UFS.

“Working at the ISG has undoubtedly been the best experience of my life and made me the solid scholar I am today. At the ISG, I found the best working environment you could possibly have in an academic setting, even compared to the Northern Hemisphere,” Dr Grilli says.

He believes the centre’s strength lies in the “exceptional exchange” that researchers have with their peers, allowing them to not only master their research subject but also to learn from other members’ research and methodologies.

“In my view, the ISG is concretely contributing to bringing the centre of African studies back to the African continent,” he enthuses.

Passion for Southern African politics

Dr Grilli specialises in the political history of Ghana and Southern Africa, focusing on transnational histories of African liberation movements, the history of Pan-Africanism, the Cold War and decolonisation in Africa, and the history of European migrations in sub-Saharan Africa (particularly Italian communities in Ghana and the Congo DRC).

He is currently working on a book project about the history of Pan-Africanism, Socialism, and Nationalism in Southern Africa, particularly in Lesotho, eSwatini, and Botswana.

Asked what advice he had for young researchers, he echoes the counsel he received from Prof Phimister at the start of his tenure at the ISG:

“Always aim high. Don’t be intimidated by the fact that there is a lot of competition in the academia, nor that you might be disadvantaged because you work in the Global South. If you work hard, your research will speak for itself and you will be able to publish solid works even in the most prestigious journals of the Northern Hemisphere.”

News Archive

Inaugural lecture: Prof Robert Bragg, Dept. of Microbial, Biochemical and Food Biotechnology

2006-05-17

Attending the inaugural lecture were in front from the left Prof Robert Bragg (lecturer at the Department of Microbial, Biochemical and Food Biotechnology) and Frederick Fourie (Rector and Vice-Chancellor). At the back from the left were Prof James du Preez (Departmental Chairperson: Department of Microbial, Biochemical and Food Biotechnology) and Prof Herman van Schalkwyk (Dean: Faculty of Natural and Agricultural Sciences). Photo: Stephen Collett

A summary of an inaugural lecture delivered by Prof Robert Bragg at the University of the Free State:

CONTROL OF INFECTIOUS AVIAN DISEASES – LESSONS FOR MAN?

Prof Robert R Bragg
Department of Microbial, Biochemical and Food Biotechnology
University of the Free State

“Many of the lessons learnt in disease control in poultry will have application on human medicine,” said Prof Robert Bragg, lecturer at the University of the Free State’s (UFS) Department of Microbial, Biochemical and Food Biotechnology during his inaugural lecture.

Prof Bragg said the development of vaccines remains the main stay of disease control in humans as well as in avian species. Disease control can not rely on vaccination alone and other disease-control options must be examined.

“With the increasing problems of antibiotic resistance, the use of disinfection and bio security are becoming more important,” he said.

“Avian influenza (AI) is an example of a disease which can spread from birds to humans. Hopefully this virus will not develop human to human transmission,” said Prof Bragg.

According to Prof Bragg, South Africa is not on the migration route of water birds, which are the main transmitters of AI. “This makes South Africa one of the countries less likely to get the disease,” he said.

If the AI virus does develop human to human transmission, it could make the 1918 flu pandemic pale into insignificance. During the 1918 flu pandemic, the virus had a mortality rate of only 3%, yet more than 50 million people died.

Although the AI virus has not developed human-to-human transmission, all human cases have been related to direct contact with infected birds. The mortality rate in humans who have contracted this virus is 67%.

“Apart from the obvious fears for the human population, this virus is a very serious poultry pathogen and can cause 100% mortality in poultry populations. Poultry meat and egg production is the staple protein source in most countries around the world. The virus is currently devastating the poultry industry world-wide,” said Prof Bragg.

Prof Bragg’s research activities on avian diseases started off with the investigation of diseases in poultry. “The average life cycle of a broiler chicken is 42 days. After this short time, they are slaughtered. As a result of the short generation time in poultry, one can observe changes in microbial populations as a result of the use of vaccines, antibiotics and disinfectants,” said Prof Bragg.

“Much of my research effort has been directed towards the control of infectious coryza in layers, which is caused by the bacterium Avibacterium paragallinarum. This disease is a type of sinusitis in the layer chickens and can cause a drop in egg product of up to 40%,” said Prof Bragg.

The vaccines used around the world in an attempt to control this disease are all inactivated vaccines. One of the most important points is the selection of the correct strains of the bacterium to use in the vaccine.

Prof Bragg established that in South Africa, there are four different serovars of the bacterium and one of these, the serovar C-3 strain, was believed to be unique to Southern Africa. He also recently discovered this serovar for the first time in Israel, thus indicating that this serovar might have a wider distribution than originally believed.

Vaccines used in this country did not contain this serovar. Prof Bragg established that the long term use of vaccines not containing the local South African strain resulted in a shift in the population distribution of the pathogen.

Prof Bragg’s research activities also include disease control in parrots and pigeons. “One of the main research projects in my group is on the disease in parrots caused by the circovirus Beak and Feather Disease virus. This virus causes serious problems in the parrot breeding industry in this country. This virus is also threatening the highly endangered and endemic Cape Parrot,” said Prof Bragg.

Prof Bragg’s research group is currently working on the development of a DNA vaccine which will assist in the control of the disease, not only in the parrot breeding industry, but also to help the highly endangered Cape Parrot in its battle for survival.

“Not all of our research efforts are directed towards infectious coryza or the Beak and Feather Disease virus. One of my Masters students is currently investigating the cell receptors involved in the binding of Newcastle Disease virus to cancerous cells and normal cells of humans. This work will also eventually lead to a possible treatment of cancer in humans and will assist with the development of a recombinant vaccine for Newcastle disease virus,” said Prof Bragg.

We are also currently investigating an “unknown” virus which causes disease problems in poultry in the Western Cape,” said Prof Bragg.

“Although disinfection has been extensively used in the poultry industry, it has only been done at the pre-placement stage. In other words, disinfectants are used before the birds are placed into the house. Once the birds are placed, all use of disinfectants stops,” said Prof Bragg.

“Disinfection and bio security can be seen as the ‘Cinderella’ of disease control in poultry. This is also true for human medicine. One just has to look at the high numbers of people who die from hospital-acquired infections to realise that disinfection is not a concept which is really clear in human health care,” said Prof Bragg.

Much research has been done in the control of diseases through vaccination and through the use of antibiotics. “These pillars of disease control are, however, starting to crumble and more effort is needed on disinfection and bio security,” said Prof Bragg.

Prof Bragg has been working in close co-operation with a chemical manufacturing company in Stellenbosch to develop a unique disinfectant which his highly effective yet not toxic to the birds.

As a result of this unique product, he has developed the continual disinfection program for use in poultry. In this program the disinfectant is used throughout the production cycle of the birds. It is also used to ensure that there is excellent pre-placement disinfection.

“The program is extensively used for the control of infectious diseases in the parrot-breeding industry in South Africa and the product has been registered in 15 countries around the world with registration in the USA in the final process,” said Prof Bragg.

“Although the problem of plasmid mediated resistance to disinfectants is starting to rear its ugly head, this has allowed for the opening of a new research field which my group will hopefully exploit in the near future,” he said.

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