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20 January 2021 | Story Leonie Bolleurs | Photo Supplied
Dr Anamika Megwalu, an assessment and engineering librarian at San Jose State University in California in the United States (US), addressed a group of staff from the UFS Department of Library and Information Services.

Dr Anamika Megwalu, an assessment and engineering librarian at San Jose State University in California in the United States (US), pointed out that building a lasting and sustainable relationship with departments and upholding quality in the library environment is key. 

She addressed a group of colleagues from our Department of Library and Information Services (LIS) on 25 November 2020.

Tight budgets call for proper assessment

Her presentation, titled Library Collection Development, was aimed at sharing her experience of working in the collection development and liaison sections within the LIS ecosystem. 

“This librarian-cum-computer science lecturer has the benefit of both worlds, having worked in private and public academic libraries such as Stafford University and City University of New York respectively,” says Monde Madiba, Deputy Director: Collection Development and Management of LIS at the University of the Free State.

San Jose, the oldest public university in the western US, is located in the heart of Silicon Valley, serving more than 33 000 students enrolled in 10 colleges and 67 departments.

According to Dr Megwalu, the tight budgets that public academic libraries such as San Jose receive, call for proper assessment of library collections in order to deal with the constraints. She emphasised the need to “uphold quality within the constraints”.

Moving from collecting information to creating information

Some of the ideas that Dr Megwalu shared for conducting assessment and collection development, includes the following:
• Change the library’s image from being a collector of information to being the creator of information.
• Consider the size of the different departments: some may need little or no attention due to size, while others may need close attention due to intensive research by lecturers within the department.
• Identify gaps and focus your attention on filling them with the relevant collection.
• Make sure that you are aware of the accreditation period of different programmes, since the role that academic libraries play in collection development is recognised by such agencies.
• Build a lasting and sustainable relationship with departments. This includes knowing the lecturers’ research interests, assisting the newly established departments, attending free webinars, and participating in student activities.
• Ensure equal distribution of the budget and ensure that everyone has equal access to it.
• Create a timetable where everyone knows when to submit requests for prescribed books. Make it clear that it takes approximately three weeks on average for ordered books to be delivered.
• Develop department-specific collection development policies.
• Be ready to move with the times, e.g. replace DVDs in favour of video-streaming services.
• Shift towards a 100% electronic reference collection.
• Consider having an electronic version for popular but currently in-print collections.
• Develop an indigenous collection based on the contributions of communities around the university.
• Create a portal for open educational resources (OERs) from participating institutions across the globe.

“Dr Megwalu’s presentation was not only informative but a testimony that collection development and assessment are dynamic and driven by passion and love,” says Madiba.

News Archive

UFS study on cell development in top international science journal
2008-09-16

A study from the University of the Free State (UFS) on how the change in the packaging of DNA with cell development influenced the expression of genes, will be published in this week’s early edition of the prestigious international, peer-reviewed science journal, the Proceeding of the National Academy of Sciences of the USA (PNAS).

The PNAS journal has an impact factor of 10, which means that studies published in the journal are, on average, referred to by ten other scientific studies in a two year period. The South African Journal of Science, by comparison, has an impact factor of 0.7.

The UFS study, funded by the Wellcome Trust and the National Research Foundation (NRF), looked at how the change in the packaging of DNA with cell development influenced the expression of genes. It is very relevant to research on stem cells, an area of medicine that studies the possible use of undifferentiated cells to replace damaged tissue.

Prof. Hugh Patterton, of the Department of Microbial, Biochemical and Food Biotechnology at the UFS, who led the study, said: "We are extremely proud of this study. It was conceived in South Africa, it was performed in South Africa, the data were analysed in South Africa, and it was published from South Africa."

When a gene is expressed, the information encoded in the gene is used to manufacture a specific protein. In eukaryotes, which include humans, there is approximately 1m of DNA, containing the genes, in every cell. This length of DNA has to fit into a cell nucleus with a diameter of only about 10 micrometer. In order to fit the DNA into such a small volume, eukaryotic cells wrap their DNA onto successive protein balls, termed nucleosomes. Strings of nucleosomes, resembling a bead of pearls, is folded into a helix to form a chromatin fiber. The study from the UFS investigated how the binding of a specific protein, termed a linker histone, that binds to the length of DNA between nucleosomes, influenced the formation of the chromatin fiber and also the activity of genes.

"We found that the linker histone bound to chromatin in yeast, which we use as a model eukaryote, under conditions where virtually all the genes in the organism were inactive. It was widely believed that the binding of the linker histone caused the inactivation of genes. We studied the relationship between the amount of linker histone bound in the vicinity of each gene and the expression of that gene for all the genes in yeast, using genomic techniques. We made the surprising discovery that even through the linker histone preferentially bound to genes under conditions where the genes were shut off, this inactivation of genes was not caused by the binding of the linker histone and folding of the chromatin,” said Prof. Patterton.

He said: “Instead our data strongly suggested that the observed anti-correlation was due to the movement of enzymes along the DNA molecule, involved in processing the information in genes for the eventual manufacture of proteins. This movement of enzymes displaced the linker histones from the DNA. This finding now requires a rethink on aspects of how packaging of DNA influences gene activity."

Prof. Patterton said that his research group, using the Facility for Genomics and Proteomics as well as the Bioinformatics Node at the UFS, was currently busy with follow-up studies to understand how other proteins in nucleosomes affected the activities of genes, as well as with projects to understand how chemicals found in red wine and in green tea extended lifespan. "We are certainly having a marvelous time trying to understand the fundamental mechanisms of life, and the UFS is an exciting place to be if one was interested in studying life at the level of molecules," he said.


Media Release
Issued by: Lacea Loader
Assistant Director: Media Liaison
Tel: 051 401 2584
Cell: 083 645 2454
E-mail: loaderl.stg@ufs.ac.za  
18 September 2008
 

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