Latest News Archive

Please select Category, Year, and then Month to display items
Previous Archive
30 June 2021 | Story André Damons | Photo André Damons
Dr Nicholas Pearce, Head of the COVID-19 Task Team at the Universitas Academic Hospital, leads a dedicated team of professionals at the testing and vaccination site of the Universitas Academic Hospital, adjacent to our Bloemfontein Campus.

It is impossible to quantify the number of hours Dr Nicholas Pearce, Head of the COVID-19 Task Team for the Universitas Academic Hospital, spent working in response to this deadly virus since the first case was reported in South Africa last year. 

According to Dr Pearce, who is the Head of the Department of General Surgery in the Faculty of Health Sciences at the University of the Free State (UFS), the initial preparation phase required many hours of brainstorming, planning, and physical hours working on site. He also spent countless hours awake at night trying to come up with solutions for the many challenges faced along the way. This is in addition to being available telephonically twenty-four-seven for any issues related to equipment, staffing, and facilities.

“I was attending a vascular surgery congress in Germany last year January (2020) when China just announced the outbreak of COVID-19. I noticed an increased number of travellers wearing surgical masks at an airport in the Middle East when I was travelling to South Africa. 

“Upon my return to work, I approached management to discuss procurement of PPEs, as it was just a matter of time before COVID-19 would hit South Africa and the rest of the world. When things escalated, I was asked to head the COVID-19 response team at Universitas Hospital,” explains Dr Pearce.

Kind human being with a soft heart

(Photo: André Damons)

Dr Pearce, who was brought up to always strive to be better, is driven and motivated to succeed. He has a very analytical brain and loves challenges. In fact, he does not believe in problems and only sees challenges. This kind human being can sometimes seem quite tough on the outside, but actually has a very soft heart. 

“I think it is human nature to want to feel needed. I have an inherent urge to help my fellow human beings. This is also the reason why I became a health-care professional and why I am passionate about teaching,” says Dr Pearce. 

With South Africa lagging behind with its vaccination programme, the hard work is far from over for Dr Pearce and his team. Says Dr Pearce: “The initiation of a mass vaccination site posed a whole new set of challenges, which once again required many hours of planning. The initial stages of running the vaccination site required many hours of physical hard work a day. Then there is also the daily operations meeting at 18:00 every weekday to discuss the vaccine roll-out in the province.”

Frustrations and setbacks

For Dr Pearce, this pandemic highlighted the differences between individuals from different social classes in our country. Providing quarantine and self-isolation facilities for individuals who do not have access to such facilities at home is one such example. 

“We all have a right to clean water and good quality healthcare. This also includes a right to oxygen. This right to oxygen has proved to be one of our great challenges in managing this pandemic. Delivery of these large amounts of oxygen has been especially challenging. Some days we require in excess of five tons of oxygen,” says Dr Pearce. 

(Photo: André Damons)


There have been many frustrations and setbacks on this journey, some of which can be quite demoralising and demotivating, but knowing that he is doing something good for his fellow human beings gives this gentle and diligent healthcare worker a tremendous amount of energy. “Positive feedback from patients and colleagues far outshines all the frustrations and disappointments,” concludes Dr Pearce. 


Outside of work

After finishing online meetings at home, Dr Pearce relaxes with his partner by chatting about the day’s events and cooking supper together while enjoying a glass of wine. He also tries to connect with family who lives in Gauteng. Because of work pressures and the pandemic, he has not been able to see them as much. 

News Archive

Nuclear Medicine on the forefront of cancer research
2017-07-10

Description: Nuclear Medicine on the forefront of cancer research Tags: Nuclear Medicine, cancer research, Dr Je’nine Horn-Lodewyk’s, tumour detection method, cancer, Department of Nuclear Medicine 

Dr Je’nine Horn-Lodewyk’s tumour detection method
could be the cost-effective breakthrough needed to decrease
the mortality rate in breast cancer patients.
Photo: Anja Aucamp

The field of Nuclear Medicine in South Africa and the rest of the world are expanding rapidly due to the development of hybrid cameras and new radiopharmaceuticals. These developments have a huge impact on the diagnosis and therapy of cancer.

The most advanced of these cameras, Positron emission tomography combined with normal CTs (PETCT), are not yet widely available in South Africa due to the cost of the cameras and the radiopharmaceuticals. A more cost-effective alternative can be of great benefit. To achieve this, the focus should be on developing new radiopharmaceuticals that can be used with the current cost-effective gamma cameras, according to University of the Free State researcher, Dr Je’nine Horn-Lodewyk from the Department of Nuclear Medicine.

Fluorodeoxyglucose (18F-FDG), a radiolabelled glucose analogue, is currently the radiopharmaceutical most commonly used in PET/CT imaging for mainly oncology indications. Although it is considered the gold standard for imaging in several malignancies, it does have certain disadvantages. An 18F-FDG PET/CT diagnostic imaging study can cost between R25 000 and R35 000 for a single patient in the private sector. The 18F-FDG is also more radioactive, which requires much stricter handling and shielding to avoid high radiation dosages to staff and patients.

Successful research potential innovative solution
In the search for the ideal radiopharmaceutical for tumour detection, the South African National Nuclear Energy Corporation (Necsa) developed a local synthesis process for ethylenedicysteine-deoxyglucose (EC-DG). EC-DG is also a glucose analogue similar to FDG. They succeeded in labelling the compound with Technetium-99-metastable-pertechnetate (99mTcO4-), the most common nuclear medicine isotope used for approximately 95% of nuclear medicine procedures, creating 99mTc-EC-DG.

In partnership with Dr Horn-Lodewyk, this compound was successfully used in various animal models and clinical scenarios, resulting in approval by the Medicine Control Council to use it in a human study. Research is also planned in order to investigate diagnostic accuracy in other cancers like lymphoma.  The end result of this research can produce a radiopharmaceutical that is cost effective, does not require the use of costly specialised equipment, has no significant side-effects, no special patient preparation, renders late imaging possible, and has decreased radiation risks.

Dr Horn-Lodewyk is grateful for the support of her mentor, Prof Anton Otto, as well as Dr Gert Engelbrecht, Head of the Department of Nuclear Medicine, Prof Jan Rijn Zeevaart from North-West University’s Preclinical Drug Development Platform and Necsa, and Judith Wagener from Necsa. This innovative research would also not have been possible without the financial assistance of Dr Glen Taylor and Eleanor van der Westhuizen in the Directorate of Research Development.

We use cookies to make interactions with our websites and services easy and meaningful. To better understand how they are used, read more about the UFS cookie policy. By continuing to use this site you are giving us your consent to do this.

Accept