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Dr Nicholas Pearce leading COVID-19 response at Universitas Academic Hospital

30 June 2021 | Story André Damons | Photo André Damons

Dr Pearce_web read more use — Dr Nicholas Pearce, Head of the COVID-19 Task Team at the Universitas Academic Hospital, leads a dedicated team of professionals at the testing and vaccination site of the Universitas Academic Hospital, adjacent to our Bloemfontein Campus.

It is impossible to quantify the number of hours Dr Nicholas Pearce, Head of the COVID-19 Task Team for the Universitas Academic Hospital, spent working in response to this deadly virus since the first case was reported in South Africa last year.

According to Dr Pearce, who is the Head of the Department of General Surgery in the Faculty of Health Sciences at the University of the Free State (UFS), the initial preparation phase required many hours of brainstorming, planning, and physical hours working on site. He also spent countless hours awake at night trying to come up with solutions for the many challenges faced along the way. This is in addition to being available telephonically twenty-four-seven for any issues related to equipment, staffing, and facilities.

“I was attending a vascular surgery congress in Germany last year January (2020) when China just announced the outbreak of COVID-19. I noticed an increased number of travellers wearing surgical masks at an airport in the Middle East when I was travelling to South Africa.

“Upon my return to work, I approached management to discuss procurement of PPEs, as it was just a matter of time before COVID-19 would hit South Africa and the rest of the world. When things escalated, I was asked to head the COVID-19 response team at Universitas Hospital,” explains Dr Pearce.

Kind human being with a soft heart

(Photo: André Damons)

Dr Pearce, who was brought up to always strive to be better, is driven and motivated to succeed. He has a very analytical brain and loves challenges. In fact, he does not believe in problems and only sees challenges. This kind human being can sometimes seem quite tough on the outside, but actually has a very soft heart.

“I think it is human nature to want to feel needed. I have an inherent urge to help my fellow human beings. This is also the reason why I became a health-care professional and why I am passionate about teaching,” says Dr Pearce.

With South Africa lagging behind with its vaccination programme, the hard work is far from over for Dr Pearce and his team. Says Dr Pearce: “The initiation of a mass vaccination site posed a whole new set of challenges, which once again required many hours of planning. The initial stages of running the vaccination site required many hours of physical hard work a day. Then there is also the daily operations meeting at 18:00 every weekday to discuss the vaccine roll-out in the province.”

Frustrations and setbacks

For Dr Pearce, this pandemic highlighted the differences between individuals from different social classes in our country. Providing quarantine and self-isolation facilities for individuals who do not have access to such facilities at home is one such example.

“We all have a right to clean water and good quality healthcare. This also includes a right to oxygen. This right to oxygen has proved to be one of our great challenges in managing this pandemic. Delivery of these large amounts of oxygen has been especially challenging. Some days we require in excess of five tons of oxygen,” says Dr Pearce.

(Photo: André Damons)

There have been many frustrations and setbacks on this journey, some of which can be quite demoralising and demotivating, but knowing that he is doing something good for his fellow human beings gives this gentle and diligent healthcare worker a tremendous amount of energy. “Positive feedback from patients and colleagues far outshines all the frustrations and disappointments,” concludes Dr Pearce.

Outside of work

After finishing online meetings at home, Dr Pearce relaxes with his partner by chatting about the day’s events and cooking supper together while enjoying a glass of wine. He also tries to connect with family who lives in Gauteng. Because of work pressures and the pandemic, he has not been able to see them as much.

News Archive

Nanotechnology breakthrough at UFS

2010-08-19

Ph.D students, Chantel Swart and Ntsoaki Leeuw

Scientists at the University of the Free State (UFS) made an important breakthrough in the use of nanotechnology in medical and biological research. The UFS team’s research has been accepted for publication by the internationally accredited Canadian Journal of Microbiology.

The UFS study dissected yeast cells exposed to over-used cooking oil by peeling microscopically thin layers off the yeast cells through the use of nanotechnology.

The yeast cells were enlarged thousands of times to study what was going on inside the cells, whilst at the same time establishing the chemical elements the cells are composed of. This was done by making microscopically small surgical incisions into the cell walls.

This groundbreaking research opens up a host of new uses for nanotechnology, as it was the first study ever in which biological cells were surgically manipulated and at the same time elemental analysis performed through nanotechnology. According to Prof. Lodewyk Kock, head of the Division Lipid Biotechnology at the UFS, the study has far reaching implications for biological and medical research.

The research was the result of collaboration between the Department of Microbial, Biochemical and Food Biotechnology, the Department of Physics (under the leadership of Prof. Hendrik Swart) and the Centre for Microscopy (under the leadership of Prof.Pieter van Wyk).

Two Ph.D. students, Chantel Swart and Ntsoaki Leeuw, overseen by professors Kock and Van Wyk, managed to successfully prepare yeast that was exposed to over-used cooking oil (used for deep frying of food) for this first ever method of nanotechnological research.

According to Prof. Kock, a single yeast cell is approximately 5 micrometres long. “A micrometre is one millionth of a metre – in laymen’s terms, even less than the diameter of a single hair – and completely invisible to the human eye.”

Through the use of nanotechnology, the chemical composition of the surface of the yeast cells could be established by making a surgical incision into the surface. The cells could be peeled off in layers of approximately three (3) nanometres at a time to establish the effect of the oil on the yeast cell’s composition. A nanometre is one thousandth of a micrometre.

Each cell was enlarged by between 40 000 and 50 000 times. This was done by using the Department of Physics’ PHI700 Scanning Auger Nanoprobe linked to a Scanning Electron Microscope and Argon-etching. Under the guidance of Prof. Swart, Mss. Swart en Leeuw could dissect the surfaces of yeast cells exposed to over-used cooking oil.

The study noted wart like outgrowths - some only a few nanometres in diameter – on the cell surfaces. Research concluded that these outgrowths were caused by the oil. The exposure to the oil also drastically hampered the growth of the yeast cells. (See figure 1)

Researchers worldwide have warned about the over-usage of cooking oil for deep frying of food, as it can be linked to the cause of diseases like cancer. The over-usage of cooking oil in the preparation of food is therefore strictly regulated by laws worldwide.

The UFS-research doesn’t only show that over-used cooking oil is harmful to micro-organisms like yeast, but also suggests how nanotechnology can be used in biological and medical research on, amongst others, cancer cells.

Figure 1. Yeast cells exposed to over-used cooking oil. Wart like protuberances/ outgrowths (WP) is clearly visible on the surfaces of the elongated yeast cells. With the use of nanotechnology, it is possible to peel off the warts – some with a diameter of only a few nanometres – in layers only a few nanometres thick. At the same time, the 3D-structure of the warts as well as its chemical composition can be established.

Media Release
Issued by: Mangaliso Radebe
Assistant Director: Media Liaison
Tel: 051 401 2828
Cell: 078 460 3320
E-mail: radebemt@ufs.ac.za
18 August 2010

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