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30 June 2021 | Story André Damons | Photo André Damons
Dr Nicholas Pearce, Head of the COVID-19 Task Team at the Universitas Academic Hospital, leads a dedicated team of professionals at the testing and vaccination site of the Universitas Academic Hospital, adjacent to our Bloemfontein Campus.

It is impossible to quantify the number of hours Dr Nicholas Pearce, Head of the COVID-19 Task Team for the Universitas Academic Hospital, spent working in response to this deadly virus since the first case was reported in South Africa last year. 

According to Dr Pearce, who is the Head of the Department of General Surgery in the Faculty of Health Sciences at the University of the Free State (UFS), the initial preparation phase required many hours of brainstorming, planning, and physical hours working on site. He also spent countless hours awake at night trying to come up with solutions for the many challenges faced along the way. This is in addition to being available telephonically twenty-four-seven for any issues related to equipment, staffing, and facilities.

“I was attending a vascular surgery congress in Germany last year January (2020) when China just announced the outbreak of COVID-19. I noticed an increased number of travellers wearing surgical masks at an airport in the Middle East when I was travelling to South Africa. 

“Upon my return to work, I approached management to discuss procurement of PPEs, as it was just a matter of time before COVID-19 would hit South Africa and the rest of the world. When things escalated, I was asked to head the COVID-19 response team at Universitas Hospital,” explains Dr Pearce.

Kind human being with a soft heart

(Photo: André Damons)

Dr Pearce, who was brought up to always strive to be better, is driven and motivated to succeed. He has a very analytical brain and loves challenges. In fact, he does not believe in problems and only sees challenges. This kind human being can sometimes seem quite tough on the outside, but actually has a very soft heart. 

“I think it is human nature to want to feel needed. I have an inherent urge to help my fellow human beings. This is also the reason why I became a health-care professional and why I am passionate about teaching,” says Dr Pearce. 

With South Africa lagging behind with its vaccination programme, the hard work is far from over for Dr Pearce and his team. Says Dr Pearce: “The initiation of a mass vaccination site posed a whole new set of challenges, which once again required many hours of planning. The initial stages of running the vaccination site required many hours of physical hard work a day. Then there is also the daily operations meeting at 18:00 every weekday to discuss the vaccine roll-out in the province.”

Frustrations and setbacks

For Dr Pearce, this pandemic highlighted the differences between individuals from different social classes in our country. Providing quarantine and self-isolation facilities for individuals who do not have access to such facilities at home is one such example. 

“We all have a right to clean water and good quality healthcare. This also includes a right to oxygen. This right to oxygen has proved to be one of our great challenges in managing this pandemic. Delivery of these large amounts of oxygen has been especially challenging. Some days we require in excess of five tons of oxygen,” says Dr Pearce. 

(Photo: André Damons)


There have been many frustrations and setbacks on this journey, some of which can be quite demoralising and demotivating, but knowing that he is doing something good for his fellow human beings gives this gentle and diligent healthcare worker a tremendous amount of energy. “Positive feedback from patients and colleagues far outshines all the frustrations and disappointments,” concludes Dr Pearce. 


Outside of work

After finishing online meetings at home, Dr Pearce relaxes with his partner by chatting about the day’s events and cooking supper together while enjoying a glass of wine. He also tries to connect with family who lives in Gauteng. Because of work pressures and the pandemic, he has not been able to see them as much. 

News Archive

Link between champagne bubbles and the UFS?
2012-11-16

Prof. Lodewyk Kock with an example of a front page of the publication FEMS Yeast Research, as adapted by F. Belliard, FEMS Central Office.
Photo: Leatitia Pienaar
15 November 2012

What is the link between the bubbles in champagne and breakthrough research being done at the Mayo Clinic in America? Nano research being done at our university.

Prof. Lodewyk Kock of Biotechnology says a human being consists of millions of minute cells that are invisible to the eye. The nano technology team at the UFS have developed a technique that allows researchers to look into such a cell, as well as other microorganisms. In this way, they can get an idea of what the cell’s “insides” look like.

The UFS team – consisting of Profs. Kock, Hendrik Swart (Physics), Pieter van Wyk (Centre for Microscopy), as well as Dr Chantel Swart (Biotechnology), Dr Carlien Pohl (Biotechnology) and Liza Coetsee (Physics) – were amazed to see that the inside of cells consist of a maze of small tunnels or blisters. Each tunnel is about 100 and more nanometres in diameter – about one ten thousandth of a millimetre – that weaves through the cells in a maze.

It was also found that these tunnels are the “lungs” of the cells. Academics doing research on yeast have had to sit up and take notice of the research being done at the UFS – to the extent that these “lungs” will appear on the front page of the highly acclaimed FEMS Yeast Research for all of 2013.

The Mayo Clinic, in particular, now wants to work with the UFS to study cancer cells in more detail in order to fight this disease, says Prof. Kock. The National Cancer Institute of America has also shown interest. This new nano technology for biology can assist in the study and development of nano medicine that can be used in the treatment of cancer and other life threatening diseases. Nano medicine uses nano metal participles that are up to one billionth of a metre in size.

Prof. Kock says laboratory tests indicate that nano medicine can improve the efficacy of anti-cancer medicine, which makes the treatment less toxic. “According to the Mayo Clinic team, nano particles are considered as a gold cartridge which is being fired directly at a cancer tumour. This is compared to fine shot that spreads through the body and also attacks healthy cells.”

“This accuracy implies that the chemotherapy dose can be lowered with fewer side effects. The Mayo Clinic found that one-tenth of the normal dosage is more effective against pancreas cancer in this way than the full dosage with a linkage to nano particles. According to the clinic, this nano medicine could also delay the spread of cancer,” says Prof. Kock.

The nano particles are used as messengers that convey anti-cancer treatment to cancer cells, where it then selectively kills the cancer cells. The transport and transfer of these medicines with regard to gold nano particles can be traced with the UFS’s nano technology to collect more information, especially where it works on the cell.

“With the new nano technology of the UFS, it is possible to do nano surgery on the cells by slicing the cells in nanometre thin slices while the working of the nano medicine is studied. In this way, it can be established if the nano medicine penetrates the cells or if it is only associated with the tiny tunnels,” says Prof. Kock.

And in champagne the small “lungs” are responsible for the bubbles. The same applies to beer and with this discovery a whole new reach field opens for scientists.

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