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15 June 2021 | Story Dr Nitha Ramnath

Prof Francis Petersen, Rector and Vice-Chancellor of the University of Free State, South Africa, invites us to rethink our relationship with the world in a series of ‘Courageous Conversations’ on the theme of ‘The Global Citizen’.

Prof Petersen argues that COVID-19 has been a powerful ‘disruptor’ - it has given us a stark reminder of the need to rethink our identity, of where we belong, our ‘normative’ view of citizenship – if we want to secure long-term survival of our civilisation and the environments which support it.

Powerful voices from public life, intellectuals, public interest and business leaders, academics, naturalists, religious leaders, astrophysicists, economists, and ecologists, and others, will be invited to share and debate their views.

Global Citizen courageous conversation launch
In partnership with the South African Chamber of Commerce based in the United Kingdom, the series launched on 26 May 2021, in a discussion with Prof Petersen on the concept and context of his thinking and how the series will roll out.

If you were unable to join the webinar you can watch the replay on YouTube, or visit the South African Chamber of Commerce website where you'll find recordings of previous webinars.

Join our next Global Citizen conversation on 17 June 2021 with a discussion led by the Chancellor of the University of Free State, Prof Bonang Francis Mohale, a published author and respected business leader who has held chairmanships and directorships at some of South Africa’s top companies, on how we educate for Global Citizenship.

Educating a ‘Global Citizen’ – June 17, 2021 15:00 SAST
We have pleasure in inviting you to the United Kingdom - South African Chamber of Commerce’s next ‘courageous conversation’ with University of Free State Rector and Vice-Chancellor Prof Francis Petersen in his series debating ‘The Global Citizen’.  

Eminent South African business leader and UFS Chancellor, Prof Bonang Mohale, will join Prof Petersen to unwrap the role universities can play in creating a ‘Global Citizen’ mindset to effect material change in a constantly evolving and turbulent international world.  

How do universities produce research, and graduate alumni who go out into the  world, to drive and reflect the bedrock value of Global Citizenship namely that of mutual respect, for others, for all creatures, and the environment which sustains us all?

A university education can be a powerful way to push the ‘reset’ button on the baggage of upbringing and our histories - personal, cultural, national, racial – which shape our world view.  

Universities can promote informed self-reflection, curiosity, and tolerance as a driving force in how we shape our realities, understand our prejudices, promote tolerance, and animate life in a better world.  Prof Petersen and Prof Mohale will reflect on how universities can accelerate and respond with greater agility to this challenge.

Kindly RSVP for the event.

 

 

News Archive

Nuclear Medicine on the forefront of cancer research
2017-07-10

Description: Nuclear Medicine on the forefront of cancer research Tags: Nuclear Medicine, cancer research, Dr Je’nine Horn-Lodewyk’s, tumour detection method, cancer, Department of Nuclear Medicine 

Dr Je’nine Horn-Lodewyk’s tumour detection method
could be the cost-effective breakthrough needed to decrease
the mortality rate in breast cancer patients.
Photo: Anja Aucamp

The field of Nuclear Medicine in South Africa and the rest of the world are expanding rapidly due to the development of hybrid cameras and new radiopharmaceuticals. These developments have a huge impact on the diagnosis and therapy of cancer.

The most advanced of these cameras, Positron emission tomography combined with normal CTs (PETCT), are not yet widely available in South Africa due to the cost of the cameras and the radiopharmaceuticals. A more cost-effective alternative can be of great benefit. To achieve this, the focus should be on developing new radiopharmaceuticals that can be used with the current cost-effective gamma cameras, according to University of the Free State researcher, Dr Je’nine Horn-Lodewyk from the Department of Nuclear Medicine.

Fluorodeoxyglucose (18F-FDG), a radiolabelled glucose analogue, is currently the radiopharmaceutical most commonly used in PET/CT imaging for mainly oncology indications. Although it is considered the gold standard for imaging in several malignancies, it does have certain disadvantages. An 18F-FDG PET/CT diagnostic imaging study can cost between R25 000 and R35 000 for a single patient in the private sector. The 18F-FDG is also more radioactive, which requires much stricter handling and shielding to avoid high radiation dosages to staff and patients.

Successful research potential innovative solution
In the search for the ideal radiopharmaceutical for tumour detection, the South African National Nuclear Energy Corporation (Necsa) developed a local synthesis process for ethylenedicysteine-deoxyglucose (EC-DG). EC-DG is also a glucose analogue similar to FDG. They succeeded in labelling the compound with Technetium-99-metastable-pertechnetate (99mTcO4-), the most common nuclear medicine isotope used for approximately 95% of nuclear medicine procedures, creating 99mTc-EC-DG.

In partnership with Dr Horn-Lodewyk, this compound was successfully used in various animal models and clinical scenarios, resulting in approval by the Medicine Control Council to use it in a human study. Research is also planned in order to investigate diagnostic accuracy in other cancers like lymphoma.  The end result of this research can produce a radiopharmaceutical that is cost effective, does not require the use of costly specialised equipment, has no significant side-effects, no special patient preparation, renders late imaging possible, and has decreased radiation risks.

Dr Horn-Lodewyk is grateful for the support of her mentor, Prof Anton Otto, as well as Dr Gert Engelbrecht, Head of the Department of Nuclear Medicine, Prof Jan Rijn Zeevaart from North-West University’s Preclinical Drug Development Platform and Necsa, and Judith Wagener from Necsa. This innovative research would also not have been possible without the financial assistance of Dr Glen Taylor and Eleanor van der Westhuizen in the Directorate of Research Development.

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